Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (418)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00404495 | Combination of Irinotecan and Temozolomide in Children With Brain Tumors. | completed | Phase 2 | 83 | PfizerINDUSTRY | 8 | Apr 18, 2012 | clinicaltrials |
| NCT00132158 | ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors | completed | Phase 1 | 19 | St. Jude Children's Research HospitalOTHER | 1 | Apr 17, 2012 | clinicaltrials |
| Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme |
| completed |
| Phase 2 |
| 5 |
| Myrexis Inc.INDUSTRY |
| 1 |
| Apr 11, 2012 |
| clinicaltrials |
| NCT00777686 | Measuring Non-Enhancing Glioblastoma Progression | completed | — | 7 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 30, 2012 | clinicaltrials |
| NCT00581737 | Cognitive Functioning and Quality of Life in CNS Lymphoma | completed | — | 50 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 5, 2012 | clinicaltrials |
| NCT00412542 | Thalidomide and Temozolomide or Camptothecin-11 (CPT-11) in Patients With Gliomas | completed | Phase 2 | 78 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 28, 2012 | clinicaltrials |
| NCT00460395 | Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial | completed | Phase 3 | 64 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 24, 2012 | clinicaltrials |
| NCT00036569 | A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas | completed | Phase 2 | 32 | National Cancer Institute (NCI)NIH | 1 | Feb 13, 2012 | clinicaltrials |
| NCT00973557 | The Effect of Monoclonal Vascular Endothelial Growth Factor (VEGF) Antibody (Bevacizumab) on Pituitary Function | completed | — | 6 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 7, 2012 | clinicaltrials |
| NCT00071539 | Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors | completed | Phase 2 | 56 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 0 | Jan 20, 2012 | clinicaltrials |
| NCT00504660 | 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients | completed | Phase 2 | 75 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 11, 2012 | clinicaltrials |
| NCT01502241 | Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly(Methusalem) | completed | Phase 3 | 412 | Heidelberg UniversityOTHER | 2 | Dec 30, 2011 | clinicaltrials |
| NCT00817284 | Bevacizumab and Irinotecan or Bevacizumab and Temozolomide With Concomitant Radiotherapy for Primary Glioblastoma Multiforme (GBM) | completed | Phase 2 | 60 | Ulrik LassenOTHER | 1 | Nov 30, 2011 | clinicaltrials |
| NCT00892931 | Phase 2 Study MPC-6827 for Recurrent Glioblastoma Multiforme | completed | Phase 2 | 56 | Myrexis Inc.INDUSTRY | 1 | Oct 14, 2011 | clinicaltrials |
| NCT00002794 | Carboplatin Plus Vincristine in Treating Children With Retinoblastoma | completed | Phase 2 | 25 | St. Jude Children's Research HospitalOTHER | 1 | Oct 4, 2011 | clinicaltrials |
| NCT00004006 | Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma | completed | Phase 2 | 4 | St. Jude Children's Research HospitalOTHER | 1 | Oct 4, 2011 | clinicaltrials |
| NCT00715013 | Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma | completed | Phase 1 / Phase 2 | 9 | University of ZurichOTHER | 0 | Sep 15, 2011 | clinicaltrials |
| NCT00509301 | Safety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 1 | 12 | Peregrine PharmaceuticalsINDUSTRY | 1 | Aug 5, 2011 | clinicaltrials |
| NCT00010114 | Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children | completed | — | 83 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Jul 20, 2011 | clinicaltrials |
| NCT00600054 | Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma | completed | Phase 2 | 44 | YM BioSciencesINDUSTRY | 3 | Jul 6, 2011 | clinicaltrials |
| NCT00089427 | IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma | completed | Phase 1 | 24 | INSYS Therapeutics IncINDUSTRY | 1 | Jul 4, 2011 | clinicaltrials |
| NCT00024557 | Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients | completed | Phase 1 | 40 | INSYS Therapeutics IncINDUSTRY | 1 | Jun 6, 2011 | clinicaltrials |
| NCT00041587 | Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma | completed | Phase 1 / Phase 2 | 80 | INSYS Therapeutics IncINDUSTRY | 3 | Jun 6, 2011 | clinicaltrials |
| NCT00064779 | Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma | completed | Phase 1 | 18 | INSYS Therapeutics IncINDUSTRY | 1 | Jun 6, 2011 | clinicaltrials |
| NCT00076986 | The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 3 | 300 | INSYS Therapeutics IncINDUSTRY | 6 | Jun 6, 2011 | clinicaltrials |
| NCT00104091 | Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors | completed | Phase 2 | 56 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 0 | May 23, 2011 | clinicaltrials |
| NCT00154375 | Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma | completed | Phase 3 | 240 | Novartis PharmaceuticalsINDUSTRY | 1 | Apr 26, 2011 | clinicaltrials |
| NCT00053118 | Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer | completed | Phase 1 | 1 | Roswell Park Cancer InstituteOTHER | 1 | Mar 1, 2011 | clinicaltrials |
| NCT00520936 | A Study of Pemetrexed in Children With Recurrent Cancer | completed | Phase 2 | 72 | Eli Lilly and CompanyINDUSTRY | 1 | Feb 25, 2011 | clinicaltrials |
| NCT00238797 | A Phase II Exploratory, Multicentre, Open-label, Non-comparative Study of ZD1839 (Iressa) and Radiotherapy in the Treatment of Patients With Glioblastoma Multiforme | completed | Phase 2 | 36 | AstraZenecaINDUSTRY | 1 | Jan 21, 2011 | clinicaltrials |
| NCT01242566 | Temozolomide in Elderly Patients With KPS < 70(TAG) | completed | Phase 2 | 70 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 17, 2010 | clinicaltrials |
| NCT00800917 | A Study of Temsirolimus and Bevacizumab in Recurrent Glioblastoma Multiforme | completed | Phase 2 | 12 | Rigshospitalet, DenmarkOTHER | 1 | Jun 2, 2010 | clinicaltrials |
| NCT00165477 | Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 2 | 23 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 10, 2010 | clinicaltrials |
| NCT00283556 | High Dose Camptothecin-11 (CPT-11) in Recurrent Unresectable Malignant Glioma | completed | Phase 1 / Phase 2 | 30 | Kentuckiana Cancer InstituteOTHER | 1 | Jan 20, 2010 | clinicaltrials |
| NCT00392119 | MR Guided Laser Interstitial Thermal Therapy for the "Minimal Invasive" Treatment of Brain Metastasis and Primary Brain Tumors | completed | Phase 1 | 18 | BioTex, Inc.INDUSTRY | 1 | Jan 1, 2010 | clinicaltrials |
| NCT00153530 | Whole Brain Irradiation in Primary Central Nervous System (CNS) Lymphoma (PCNSL) | completed | Phase 4 | 604 | Charite University, Berlin, GermanyOTHER | 1 | Dec 24, 2009 | clinicaltrials |
| NCT00901238 | Intra-arterial Chemotherapy(Chemosurgery) for Retinoblastoma(Chemosurgery) | completed | Phase 1 / Phase 2 | 100 | Weill Medical College of Cornell UniversityOTHER | 1 | Dec 17, 2009 | clinicaltrials |
| NCT00503204 | Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour | completed | Phase 1 | 20 | AstraZenecaINDUSTRY | 2 | Nov 25, 2009 | clinicaltrials |
| NCT00224978 | Chloroquine for Treatment of Glioblastoma Multiforme | completed | Phase 3 | — | National Institute of Neurology and Neurosurgery, MexicoOTHER | 1 | Nov 18, 2009 | clinicaltrials |
| NCT00006246 | Busulfan in Treating Children and Adolescents With Refractory CNS Cancer | completed | Phase 1 | 28 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Oct 7, 2009 | clinicaltrials |
| NCT00418327 | Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma | completed | Phase 1 | 48 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Aug 7, 2009 | clinicaltrials |
| NCT00944801 | Pegylated Liposomal Doxorubicine and Prolonged Temozolomide in Addition to Radiotherapy in Newly Diagnosed Glioblastoma | completed | Phase 1 / Phase 2 | 63 | University of RegensburgOTHER | 1 | Jul 23, 2009 | clinicaltrials |
| NCT00599703 | Language Function in Patients With Brain Tumors | completed | — | 7 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 8, 2009 | clinicaltrials |
| NCT00032903 | This is an Early Study to Investigate the Effect of Gimatecan® in Adults With Malignant Glioma. | completed | Phase 1 / Phase 2 | 59 | Sigma-Tau Research, Inc.INDUSTRY | 1 | Jun 3, 2009 | clinicaltrials |
| NCT00185861 | Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma | completed | Phase 1 | 12 | Stanford UniversityOTHER | 1 | Apr 9, 2009 | clinicaltrials |
| NCT00080054 | A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas | completed | Phase 1 | 24 | Pharmacyclics LLC.INDUSTRY | 1 | Apr 3, 2009 | clinicaltrials |
| NCT00115440 | BNCT to Treat Glioma That Has Progressed Following Radiotherapy | completed | Phase 1 / Phase 2 | 22 | Boneca CorporationINDUSTRY | 1 | Jan 28, 2009 | clinicaltrials |
| NCT00157703 | G207 Followed by Radiation Therapy in Malignant Glioma | completed | Phase 1 | 9 | MediGeneINDUSTRY | 1 | Dec 16, 2008 | clinicaltrials |
| NCT00306618 | Safety and Efficacy Study of Panzem NCD to Treat Glioblastoma | completed | Phase 2 | 27 | CASI pharmaceuticals, Inc.INDUSTRY | 1 | Dec 10, 2008 | clinicaltrials |
| NCT00481455 | Phase 2 Study of Panzem Nanocrystal Colloidal Dispersion (NCD) in Combination With Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme (GBM) | completed | Phase 2 | 15 | CASI pharmaceuticals, Inc.INDUSTRY | 1 | Nov 25, 2008 | clinicaltrials |
Data updated 23 days agoSource updated Apr 18, 2012source: clinicaltrials