Clinical trial · Observational
Language Function in Patients With Brain Tumors
Reorganization of Language Function in Patients With Brain Tumors
NCT00599703CI-TRIAL-00002446completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to use an imaging method called functional magnetic resonance imaging (fMRI) in patients who have a tumor near an area of the brain that is believed to control language. The fMRI is a new kind of imaging that uses a strong magnetic field to look at functioning brain tissue. This kind of imaging will be used to study the effect of the brain tumor on your speech.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Cancer | Malignant Brain Neoplasm | ALIAS | 0.90 |
| CNS Cancer | Malignant Central Nervous System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| fMRI Scan, pre- and post language evaluation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- 1
- description
- neurosurgical patients
- interventionNames
- Other: fMRI Scan, pre- and post language evaluation
Primary outcomes (1)
- measure
- To identify language organization prior to surgery in patients in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.
- timeFrame
- conclusion of study
Secondary outcomes (1)
- measure
- To assess language reorganization over time.
- timeFrame
- conclusion of study
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient in whom a tumor invades or is directly adjacent to the expected location of one of the language centers. * At least 18 years of age * English as first language Exclusion Criteria: * Patients with high grade tumors * History of significant psychiatric condition (e.g. schizophrenia, obsessive-compulsive disorder, significant dementia), * History of the following neurological conditions: CVA, demyelinating conditions, cerebral palsy, Alzheimer's disease. * History of significant claustrophobic reactions. * Pregnancy * Standard contraindications to MR examinations (e.g. implanted stimulator) * Patients, who were treated prior to our first scan, will not be eligible to participate in this study
References
Publications (0)
Data not yet available
No reference posted for this study.