Cancer Family
Malignant Breast Neoplasm
CI-CAN-00000227Explore in graph →
Top-level2,628 active trials43 approved drugs310 evidence items
- NCIt
- C9335
- ICD-10
- C50
- DOID
- 1612
- Other
- 2 more codes
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Cancer Family
CI-CAN-00000227Explore in graph →
Clinical trials
12,359 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,368)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01556243 | Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer | completed | Phase 2 | 270 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT06513364 | Neoadjuvant Chemotherapy With WH002 in Women With HER2-negative Breast Cancer | completed | Phase 2 | 40 | Beijing Wehand-Bio Pharmaceutical Co., LtdINDUSTRY | 1 | Jun 9, 2026 | clinicaltrials |
| NCT05181462 | Nadunolimab in Combination With Gemcitabine Plus Carboplatin in Patients With Advanced Triple Negative Breast Cancer.(TRIFOUR) | completed | Phase 1 / Phase 2 | 117 | Cantargia ABINDUSTRY | 1 | May 27, 2026 | clinicaltrials |
| NCT04296162 | Oral Vinorelbine or Capecitabine Combined With Trastuzumab as Adjuvant Treatment for Patients With Lymph Node Negative, HER-2 Positive and Small Tumor Size Breast Cancer (ORCHID)(ORCHID) | completed | Phase 2 | 182 | Fudan UniversityOTHER | 1 | May 26, 2026 | clinicaltrials |
| NCT03789097 | Vaccination With Flt3L, Radiation, and Poly-ICLC | completed | Phase 1 / Phase 2 | 17 | Icahn School of Medicine at Mount SinaiOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT04699630 | A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer | completed | Phase 2 | 121 | SCRI Development Innovations, LLCOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT06188559 | A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer | completed | Phase 2 | 56 | Eisai Inc.INDUSTRY | 4 | May 22, 2026 | clinicaltrials |
| NCT05900986 | LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer | completed | Phase 1 / Phase 2 | 22 | Integro TheranosticsINDUSTRY | 1 | May 20, 2026 | clinicaltrials |
| NCT00631852 | A Phase II Biomarker Trial of Gelatin Encapsulated Extract of American Ginseng Root (LEAG) in Breast Cancer | completed | Phase 2 | 16 | Southern Illinois UniversityOTHER | 1 | May 12, 2026 | clinicaltrials |
| NCT02689427 | Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer | completed | Phase 2 | 24 | M.D. Anderson Cancer CenterOTHER | 1 | May 12, 2026 | clinicaltrials |
| NCT04505826 | A Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast Cancer | completed | Phase 1 / Phase 2 | 153 | Olema Pharmaceuticals, Inc.INDUSTRY | 2 | May 11, 2026 | clinicaltrials |
| NCT04268134 | Altering Lipids for Tolerance of Aromatase Inhibitor Therapy(ALTA) | completed | Phase 2 | 77 | University of Michigan Rogel Cancer CenterOTHER | 1 | May 6, 2026 | clinicaltrials |
| NCT01670500 | Cisplatin vs. Doxorubicin/Cyclophosphamide in BrCa | completed | Phase 2 | 118 | Beth Israel Deaconess Medical CenterOTHER | 1 | May 5, 2026 | clinicaltrials |
| NCT03797326 | Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) | completed | Phase 2 | 611 | Merck Sharp & Dohme LLCINDUSTRY | 17 | May 4, 2026 | clinicaltrials |
| NCT05865990 | HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease(TUXEDO-3) | completed | Phase 2 | 63 | MedSIROTHER | 2 | May 4, 2026 | clinicaltrials |
| NCT02700386 | Shorter Course Radiation for the Treatment of Breast Cancer That Has Spread to Lymph Nodes | completed | Phase 2 | 108 | University of Colorado, DenverOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT03483012 | Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis | completed | Phase 2 | 6 | Dana-Farber Cancer InstituteOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT02630693 | Two Different Schedules of Palbociclib + Second Line Endocrine Therapy in Estrogen Receptor Positive, HER2 Neg Advanced/Metastatic Breast Cancer | completed | Phase 2 | 180 | Canadian Cancer Trials GroupNETWORK | 1 | Apr 13, 2026 | clinicaltrials |
| NCT02928978 | Ruxolitinib for Premalignant Breast Disease(TBCRC042) | completed | Phase 2 | 84 | Julie NangiaOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT02595905 | Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases | completed | Phase 2 | 344 | National Cancer Institute (NCI)NIH | 2 | Apr 8, 2026 | clinicaltrials |
| NCT07307911 | Coenzyme Q10 for Neuroprotection in Paclitaxel-Induced Neuropathy(Co-Pa-N) | completed | Phase 2 | 50 | Damanhour UniversityOTHER | 1 | Apr 8, 2026 | clinicaltrials |
| NCT05394285 | A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Anti-tumor Treatment in Advanced Breast Cancer | completed | Phase 2 | 60 | Henan Cancer HospitalOTHER_GOV | 1 | Apr 6, 2026 | clinicaltrials |
| NCT04877821 | The Efficacy and Safety of Sintilimab Plus Anlotinib Combined With Chemotherapy as Neoadjuvant Therapy in TNBC(NeoSACT) | completed | Phase 2 | 29 | Guangdong Provincial People's HospitalOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT03947151 | Efficacy and Tolerance of an Ovarian Stimulation Protocol Combining Follicle Stimulating Hormone (FSH) and Degarelix Acetate in Female Candidates for Fertility Preservation Before Chemotherapy for Breast Cancer(DEGASTIM) | completed | Phase 2 | 8 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT00066443 | Epirubicin, Docetaxel, and Pegfilgrastim in Treating Women With Locally Advanced or Inflammatory Breast Cancer | completed | Phase 1 / Phase 2 | 93 | NCIC Clinical Trials GroupNETWORK | 1 | Mar 27, 2026 | clinicaltrials |
| NCT03328026 | Combination Study of SV-BR-1-GM With Retifanlimab | completed | Phase 1 / Phase 2 | 36 | BriaCell Therapeutics CorporationINDUSTRY | 1 | Mar 27, 2026 | clinicaltrials |
| NCT05376241 | Promoting Informed Choice for Breast Cancer Screening | completed | Phase 2 | 637 | University of Colorado, DenverOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT04539938 | A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer(HER2CLIMB-04) | completed | Phase 2 | 70 | Seagen, a wholly owned subsidiary of PfizerINDUSTRY | 1 | Mar 23, 2026 | clinicaltrials |
| NCT05963997 | A Study of Samuraciclib and Elacestrant in Participants With Metastatic or Locally Advanced HR+/HER2-negative Breast Cancer(SUMIT-ELA) | completed | Phase 1 / Phase 2 | 49 | Carrick Therapeutics LimitedINDUSTRY | 4 | Mar 23, 2026 | clinicaltrials |
| NCT03709446 | Leflunomide in Previously Treated Metastatic Triple Negative Cancers | completed | Phase 1 / Phase 2 | 17 | Joseph SparanoOTHER | 1 | Mar 19, 2026 | clinicaltrials |
| NCT05659563 | Preoperative Window Opportunity Study With Giredestrant or Tamoxifen in Premenopausal Women With ER+/HER2[-] & Ki67≥10%(EMPRESS) | completed | Phase 2 | 92 | MedSIROTHER | 2 | Mar 19, 2026 | clinicaltrials |
| NCT05340413 | Predicting Olaparib Sensitivity in Patients With Unresectable Locally Advanced/Metastatic HER2-negative Breast Cancer.(RADIOLA) | completed | Phase 2 | 65 | SOLTI Breast Cancer Research GroupOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT02779855 | Talimogene Laherparepvec in Combination With Neoadjuvant Chemotherapy in Triple Negative Breast Cancer | completed | Phase 1 / Phase 2 | 50 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT04332653 | NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 215 | NeoImmuneTechINDUSTRY | 1 | Mar 9, 2026 | clinicaltrials |
| NCT01560416 | Fulvestrant With or Without Ganetespib in HR+ Breast Cancer | completed | Phase 2 | 50 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT05896566 | A Window-of-Opportunity Trial of Giredestrant +/- Triptorelin vs. Anastrozole + Triptorelin in Premenopausal Patients With ER-positive/HER2-negative Early Breast Cancer(PREcoopERA) | completed | Phase 2 | 231 | ETOP IBCSG Partners FoundationNETWORK | 6 | Feb 24, 2026 | clinicaltrials |
| NCT00003042 | Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer | completed | Phase 2 | 41 | City of Hope Medical CenterOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT01853748 | T-DM1 vs Paclitaxel/Trastuzumab for Breast (ATEMPT Trial) | completed | Phase 2 | 512 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 19, 2026 | clinicaltrials |
| NCT02530489 | Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer | completed | Phase 2 | 37 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT03301350 | Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer | completed | Phase 2 | 29 | University of Wisconsin, MadisonOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT05101564 | Umbrella Trial of Subtype-Targeted Therapies in ER+/HER2- Breast Cancer | completed | Phase 2 | 19 | Jennifer Lee Caswell-JinOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT06009627 | Study of Neoadjuvant Endocrine Therapy in HR Positive and HER2 Negative Premenopausal Breast Cancer Patients | completed | Phase 2 / Phase 3 | 119 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT02520063 | Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer | completed | Phase 1 / Phase 2 | 15 | University of Alabama at BirminghamOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT03025035 | Pembrolizumab in Combination With Olaparib in Advanced BRCA-mutated or HDR-defect Breast Cancer | completed | Phase 2 | 14 | Yuan YuanOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT01796197 | Paclitaxel + Trastuzumab + Pertuzumab as Pre-Op for Inflammatory BrCa | completed | Phase 2 | 23 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT04275661 | Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery | completed | Phase 2 | 60 | Assiut UniversityOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT01494662 | HKI-272 for HER2-Positive Breast Cancer and Brain Metastases | completed | Phase 2 | 140 | Dana-Farber Cancer InstituteOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT02086578 | Study Assessing the Potential for Reduced Rates of Implant Failure Using Multi-Beam Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer Patients With Implant Reconstructions | completed | Phase 2 | 100 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT02668666 | Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer | completed | Phase 2 | 49 | Oana Danciu, MDOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT03056755 | Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole, Based on Prior Endocrine Therapy, in Patients With PIK3CA Mutant, HR+, HER2- Advanced Breast Cancer Who Have Progressed on or After Prior Treatments(BYLieve) | completed | Phase 2 | 383 | Novartis PharmaceuticalsINDUSTRY | 19 | Jan 13, 2026 | clinicaltrials |
Data updated 22 days agoSource updated Jun 12, 2026source: clinicaltrials