Cancer Family
Malignant Bone Marrow Neoplasm
CI-CAN-00000226Explore in graph →
1,033 active trials28 approved drugs633 evidence items
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Cancer Family
CI-CAN-00000226Explore in graph →
Clinical trials
4,614 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (803)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01597778 | Double Cord Versus Haploidentical (BMT CTN 1101) | completed | Phase 3 | 368 | Medical College of WisconsinOTHER | 1 | Dec 1, 2021 | clinicaltrials |
| NCT01404949 | Combined Tretinoin and Arsenic Trioxide for Patients With Newly Diagnosed Acute Promyelocytic Leukemia Followed by Risk-Adapted Postremission Therapy | completed | Phase 2 | 17 | Memorial Sloan Kettering Cancer CenterOTHER | 2 | Nov 30, 2021 | clinicaltrials |
| NCT04598789 | A Multicentre, Retrospective Study to Evaluate the Outcome of HSCT Mismatch Unrelated Donors | completed | — | 61 | Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'AnnaOTHER | 1 | Nov 26, 2021 | clinicaltrials |
| NCT01334086 | Aprepitant as Antiemetic Prophylaxis in Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy | completed | Phase 2 | 41 | University Health Network, TorontoOTHER | 1 | Nov 22, 2021 | clinicaltrials |
| NCT02214407 | Randomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML(GFM-DAC-CMML) | completed | Phase 3 | 170 | Groupe Francophone des MyelodysplasiesOTHER | 1 | Nov 19, 2021 | clinicaltrials |
| NCT02592447 | Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) Intervention | completed | N/A | 48 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Nov 16, 2021 | clinicaltrials |
| NCT00375219 | Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation | completed | Phase 2 | 103 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 10 | Nov 15, 2021 | clinicaltrials |
| NCT01462578 | Treatment of Patients With Myelodysplastic Syndrome or Acute Myelocytic Leukemia With an Impending Hematological Relapse With Azacitidine (Vidaza)(RELAZA2) | completed | Phase 2 | 93 | Technische Universität DresdenOTHER | 1 | Nov 15, 2021 | clinicaltrials |
| NCT01843634 | Ph I Safety and Efficacy of ODSH in Patients Receiving Induction or Consolidation Therapy for Acute Myeloid Leukemia | completed | Early Phase 1 | 10 | Jazz PharmaceuticalsINDUSTRY | 1 | Nov 10, 2021 | clinicaltrials |
| NCT02756572 | Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms | completed | Phase 2 | 30 | University of WashingtonOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT01596114 | European Stop Tyrosine Kinase Inhibitor Study(EURO-SKI) | completed | Phase 3 | 868 | European LeukemiaNetNETWORK | 10 | Nov 5, 2021 | clinicaltrials |
| NCT02660281 | URMC Related Haplo-identical Donor BMT(HaploOnly) | completed | Phase 1 | 74 | University of RochesterOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT00412360 | Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) | completed | Phase 3 | 224 | Medical College of WisconsinOTHER | 3 | Oct 28, 2021 | clinicaltrials |
| NCT03019939 | Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropenia | completed | Phase 2 | 65 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT03263637 | Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies | completed | Phase 1 | 44 | AstraZenecaINDUSTRY | 3 | Oct 22, 2021 | clinicaltrials |
| NCT03144245 | Study of AMV564 in Patients With AML | completed | Phase 1 | 53 | Amphivena Therapeutics, Inc.INDUSTRY | 1 | Oct 12, 2021 | clinicaltrials |
| NCT02464657 | Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) | completed | Phase 1 / Phase 2 | 44 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 7, 2021 | clinicaltrials |
| NCT02328755 | Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid Leukemia | completed | Phase 1 / Phase 2 | 37 | University of Michigan Rogel Cancer CenterOTHER | 1 | Oct 6, 2021 | clinicaltrials |
| NCT05057299 | Extramedullary Acute Myeloid Leukemia (eAML): Retrospective Single Center Cohort Study, Clinicopathological, Molecular Analysis and Survival Outcomes | completed | — | 32 | King Hussein Cancer CenterOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT02497404 | Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR | completed | Phase 2 | 40 | Weill Medical College of Cornell UniversityOTHER | 1 | Sep 22, 2021 | clinicaltrials |
| NCT03881826 | Investigation of the Gut Microbiota in Patients With Acute Myeloid Leukemia(MicroAML) | completed | N/A | 60 | Université Catholique de LouvainOTHER | 1 | Sep 22, 2021 | clinicaltrials |
| NCT01731951 | Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis | completed | Phase 2 | 80 | Geron CorporationINDUSTRY | 1 | Sep 21, 2021 | clinicaltrials |
| NCT03018223 | Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT | completed | Phase 1 | 32 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT03625505 | A Study to Assess Safety and Efficacy of Venetoclax in Combination With Gilteritinib in Participants With Relapsed/Refractory Acute Myeloid Leukemia | completed | Phase 1 | 61 | AbbVieINDUSTRY | 1 | Sep 14, 2021 | clinicaltrials |
| NCT00424242 | Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases | completed | Early Phase 1 | 15 | Northwestern UniversityOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT04126707 | The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans | completed | Phase 1 | 6 | Ascentage Pharma Group Inc.INDUSTRY | 1 | Sep 8, 2021 | clinicaltrials |
| NCT02169791 | Nonmyeloablative Haploidentical Transplant Followed by MLN9708 | completed | Phase 2 | 29 | Northside Hospital, Inc.OTHER | 1 | Sep 2, 2021 | clinicaltrials |
| NCT01633372 | An Open Label Study of Itacitinib Administered Orally in Patients With Myelofibrosis | completed | Phase 2 | 87 | Incyte CorporationINDUSTRY | 3 | Aug 30, 2021 | clinicaltrials |
| NCT02249091 | A Phase II Study of Selinexor Plus Cytarabine and Idarubicin in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) | completed | Phase 2 | 42 | GSO Global Clinical Research BVOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT02144675 | Choline Magnesium Trisalicylate and Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia | completed | Phase 2 | 27 | Rutgers, The State University of New JerseyOTHER | 1 | Aug 24, 2021 | clinicaltrials |
| NCT01814475 | Study to Compare Busulfan-fludarabine With Thiotepa-fludarabine Regimen in Allogeneic Transplantation for Myelofibrosis(GITMO-MF2010) | completed | Phase 2 | 62 | Gruppo Italiano Trapianto di Midollo OsseoOTHER | 1 | Aug 20, 2021 | clinicaltrials |
| NCT03647215 | CALLS: CML and Ph+ALL Low Level Mutation Prevalence Survey | completed | — | 427 | Incyte Biosciences UKINDUSTRY | 2 | Aug 16, 2021 | clinicaltrials |
| NCT00003816 | Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer | completed | Phase 2 / Phase 3 | 361 | Roswell Park Cancer InstituteOTHER | 1 | Aug 13, 2021 | clinicaltrials |
| NCT02559557 | Culturally Adapted Parenting Intervention for Spanish-Speaking Parents in Improving Outcomes of Younger Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia Survivors at Risk for Late Neurocognitive Effects | completed | N/A | 38 | City of Hope Medical CenterOTHER | 1 | Aug 12, 2021 | clinicaltrials |
| NCT03397173 | TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid | completed | Phase 2 | 12 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 11, 2021 | clinicaltrials |
| NCT00703820 | Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia | completed | Phase 3 | 324 | St. Jude Children's Research HospitalOTHER | 2 | Aug 10, 2021 | clinicaltrials |
| NCT02708641 | A Phase II Study of Pembrolizumab as Post-Remission Treatment of Patients ≥ 60 With AML | completed | Phase 2 | 12 | Michael BoyiadzisOTHER | 1 | Aug 10, 2021 | clinicaltrials |
| NCT01020539 | Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia(AML/MDS/JMML) | completed | Phase 1 | 18 | Columbia UniversityOTHER | 1 | Aug 6, 2021 | clinicaltrials |
| NCT01953692 | A Trial of Pembrolizumab (MK-3475) in Participants With Blood Cancers (MK-3475-013/KEYNOTE-013) | completed | Phase 1 | 197 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Aug 4, 2021 | clinicaltrials |
| NCT01221857 | Pilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancies | completed | Phase 1 / Phase 2 | 12 | Gamida Cell ltdINDUSTRY | 1 | Aug 3, 2021 | clinicaltrials |
| NCT02265731 | Study Evaluating Venetoclax in Subjects With Hematological Malignancies | completed | Phase 1 / Phase 2 | 38 | AbbVieINDUSTRY | 1 | Aug 2, 2021 | clinicaltrials |
| NCT03825887 | Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients(PCA) | completed | Phase 3 | 80 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Aug 2, 2021 | clinicaltrials |
| NCT00171249 | An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia | completed | Phase 2 | 293 | Novartis PharmaceuticalsINDUSTRY | 5 | Jul 22, 2021 | clinicaltrials |
| NCT03555955 | A Trial to Evaluate the Potential Impact of Renal Impairment on the Pharmacokinetics and Safety of CPX-351 | completed | Phase 1 | 21 | Jazz PharmaceuticalsINDUSTRY | 2 | Jul 22, 2021 | clinicaltrials |
| NCT02038036 | Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy.(RESPONSE-2) | completed | Phase 3 | 149 | Novartis PharmaceuticalsINDUSTRY | 12 | Jul 20, 2021 | clinicaltrials |
| NCT00488592 | Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers | completed | Phase 2 | 10 | National Heart, Lung, and Blood Institute (NHLBI)NIH | 1 | Jul 12, 2021 | clinicaltrials |
| NCT03451084 | A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia | completed | Phase 2 | 24 | ASLAN PharmaceuticalsOTHER | 3 | Jul 6, 2021 | clinicaltrials |
| NCT00980018 | An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib Treatment(MACS0999) | completed | Phase 4 | 52 | Novartis PharmaceuticalsINDUSTRY | 2 | Jul 1, 2021 | clinicaltrials |
Data updated 24 days agoSource updated Dec 1, 2021source: clinicaltrials