Subtype
Malignant Biliary Tract Neoplasm
CI-CAN-00003139Explore in graph →
367 active trials6 approved drugs33 evidence items
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Subtype
CI-CAN-00003139Explore in graph →
Clinical trials
1,282 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (152)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03027284 | A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer | completed | Phase 1 | 19 | Eli Lilly and CompanyINDUSTRY | 1 | May 19, 2020 | clinicaltrials |
| NCT01643499 | Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies | completed | Phase 1 | 79 | University of ChicagoOTHER | 1 | May 8, 2020 | clinicaltrials |
| NCT03768531 | Safety and Tolerability Study of Nivolumab and Cabiralizumab for Resectable Biliary Tract Cancer | withdrawn | Phase 2 | 0 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 0 | Apr 13, 2020 | clinicaltrials |
| NCT03172832 | A Trial of Percutaneous vs. Endoscopic Drainage of Suspected Klatskin Tumors(INTERCPT) | terminated | N/A | 13 | Medical University of South CarolinaOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT00948935 | Study of Gemcitabine, Irinotecan and Panitumumab in Patients With Advanced and Metastatic Biliary Tract Adenocarcinoma | completed | Phase 2 | 35 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Mar 11, 2020 | clinicaltrials |
| NCT02456714 | Second Line Chemotherapy FOLFIRINOX in Irresectable Cholangiocarcinoma(4CC) | completed | Phase 2 | 30 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Mar 10, 2020 | clinicaltrials |
| NCT04300959 | Anlotinib in Combination With PD1 With Gemcitabine Plus(+)Cisplatin for Unresectable or Metastatic Biliary Tract Cancer | unknown | Phase 2 | 80 | Zhejiang Cancer HospitalOTHER | 1 | Mar 9, 2020 | clinicaltrials |
| NCT01347333 | Stereotactic Body Radiotherapy for Liver Tumors | completed | N/A | 23 | Mercy ResearchOTHER | 1 | Mar 3, 2020 | clinicaltrials |
| NCT01256047 | Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy | completed | Phase 4 | 40 | Chiba UniversityOTHER | 1 | Feb 18, 2020 | clinicaltrials |
| NCT03873532 | A Trial Evaluating Surufatinib Efficacy and Safety in Biliary Tract Carcinoma Patients | unknown | Phase 2 / Phase 3 | 298 | Hutchison Medipharma LimitedINDUSTRY | 1 | Feb 13, 2020 | clinicaltrials |
| NCT00779454 | Combined Biological Treatment and Chemotherapy for Patients With Inoperable Cholangiocarcinoma | completed | Phase 2 | 72 | Vejle HospitalOTHER | 1 | Feb 6, 2020 | clinicaltrials |
| NCT03267966 | Margin Status After Pancreaticoduodenectomy for Cancer | completed | N/A | 168 | Campus Bio-Medico UniversityOTHER | 0 | Feb 6, 2020 | clinicaltrials |
| NCT03818997 | Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer(DYNAMIC) | withdrawn | Phase 2 | 0 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | Feb 5, 2020 | clinicaltrials |
| NCT01926236 | Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers(ABC06) | completed | Phase 3 | 162 | The Christie NHS Foundation TrustOTHER | 1 | Jan 28, 2020 | clinicaltrials |
| NCT04243057 | Diagnosis, Treatment Status and Prognosis of Cholangiocarcinoma in China: a Multicenter, Two-way, Non-intervention Study | unknown | — | 5,000 | Beijing Tsinghua Chang Gung HospitalOTHER | 1 | Jan 27, 2020 | clinicaltrials |
| NCT02496741 | Metformin And Chloroquine in IDH1/2-mutated Solid Tumors(MACIST) | completed | Phase 1 / Phase 2 | 15 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Jan 9, 2020 | clinicaltrials |
| NCT02730611 | Metabolic Syndrome, Bile Acids, Hepatocellular Carcinoma and Cholangiocarcinoma(METSLIVER) | completed | — | 124 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Dec 17, 2019 | clinicaltrials |
| NCT03771846 | HAIC Versus Systemic Chemotherapy for Unresectable ICC | unknown | Phase 3 | 188 | Shi MingOTHER | 1 | Dec 5, 2019 | clinicaltrials |
| NCT02592538 | Endobiliary Radiofrequency Ablation With S-1 for Unresectable Cholangiocarcinoma | completed | N/A | 66 | First People's Hospital of HangzhouOTHER | 1 | Nov 19, 2019 | clinicaltrials |
| NCT03774589 | Bilioenteric Anastomosis by Magnetic Compressive Technique(BAMCT) | unknown | N/A | 200 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Nov 18, 2019 | clinicaltrials |
| NCT03792048 | Magnetic Compressive Anastomosis for Biliojejunostomy and Pancreaticojejunostomy During Whipple's Procedure | unknown | N/A | 50 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Nov 18, 2019 | clinicaltrials |
| NCT03211169 | Comparison Bile Duct Brushings, Cholangioscopy-Directed Biopsies and Pediatric Forceps Biopsies in Biliary Strictures | terminated | N/A | 12 | Stanford UniversityOTHER | 1 | Nov 8, 2019 | clinicaltrials |
| NCT04156958 | Fruquintinib as Second-line Treatment for Advanced/Metastatic Biliary Tract Adenocarcinoma(FSTAMBTA) | unknown | Phase 2 | 33 | Sichuan UniversityOTHER | 1 | Nov 8, 2019 | clinicaltrials |
| NCT01900158 | A Phase I/II Safety and Efficacy Study of PCI of Gemcitabine and Chemotherapy in Patients With Cholangiocarcinomas | completed | Phase 1 | 24 | PCI Biotech ASINDUSTRY | 4 | Oct 29, 2019 | clinicaltrials |
| NCT03210298 | International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)(PIPACRegis) | unknown | — | 1,000 | Sabine RhodeOTHER | 13 | Oct 8, 2019 | clinicaltrials |
| NCT04111380 | Efficacy and Safety Study of Nab-Paclitaxel Combined With Cisplatin in Second or Later-Line Treatment in Advanced Biliary Tract Cancers | unknown | Phase 2 | 30 | Henan Provincial People's HospitalOTHER | 1 | Oct 1, 2019 | clinicaltrials |
| NCT02773459 | MEK162 in Combination With Capecitabine in Advanced Biliary Tract Cancer | completed | Phase 1 / Phase 2 | 31 | Seoul National University HospitalOTHER | 1 | Sep 30, 2019 | clinicaltrials |
| NCT04072250 | Surgery for Recurrent Intrahepatic Cholangiocarcinoma | completed | — | 216 | Chang Gung Memorial HospitalOTHER | 1 | Sep 13, 2019 | clinicaltrials |
| NCT04077983 | Nab-Paclitaxel Combined With Gemcitabine Adjuvant Chemotherapy After Radical Resection of Intrahepatic Cholangiocarcinoma | unknown | Phase 2 | 40 | Shanghai Zhongshan HospitalOTHER | 0 | Sep 4, 2019 | clinicaltrials |
| NCT03042182 | Trial of Therapeutic Vaccine in Patients With Cholangiocarcinoma(cholangio) | unknown | Phase 1 / Phase 2 | 20 | Immunitor LLCINDUSTRY | 1 | Aug 30, 2019 | clinicaltrials |
| NCT02082522 | Efficacy and Safety Study of PDT Using Photofrin in Unresectable Advanced Perihilar Cholangiocarcinoma (OPUS) | terminated | Phase 3 | 28 | Concordia Laboratories Inc.INDUSTRY | 5 | Aug 28, 2019 | clinicaltrials |
| NCT02999672 | A Study to Determine Best Tumor Response With Trastuzumab Emtansine in Human Epidermal Growth Factor Receptor 2 (HER2) Overexpressing Solid Tumors(KAMELEON) | completed | Phase 2 | 20 | Hoffmann-La RocheINDUSTRY | 4 | Aug 28, 2019 | clinicaltrials |
| NCT02425137 | A Study of S-1 in Combination With Gemcitabine as First-Line Treatment in Patients With Advanced Biliary Tract Cancer | completed | Phase 2 | 51 | TTY BiopharmINDUSTRY | 1 | Aug 21, 2019 | clinicaltrials |
| NCT00478140 | Trastuzumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer or Bile Duct Cancer That Cannot Be Removed by Surgery | terminated | Phase 2 | 4 | National Cancer Institute (NCI)NIH | 1 | Aug 20, 2019 | clinicaltrials |
| NCT02002806 | Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain Control | completed | N/A | 150 | Indiana UniversityOTHER | 1 | Aug 16, 2019 | clinicaltrials |
| NCT03951324 | Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study(VLE-IOV) | unknown | — | 40 | Innovative Digestive Health Education and Research IncOTHER | 1 | Aug 12, 2019 | clinicaltrials |
| NCT02841800 | Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary Stenosis | completed | N/A | 5 | National Taiwan University HospitalOTHER | 0 | Aug 5, 2019 | clinicaltrials |
| NCT02108145 | Percutaneous Bilateral Versus Unilateral Metal Stent for Hilar Cholangiocarcinoma | unknown | Phase 2 / Phase 3 | 70 | Air Force Military Medical University, ChinaOTHER | 1 | Aug 1, 2019 | clinicaltrials |
| NCT04027764 | Toripalimab Combined With S1 and Albumin Paclitaxel in Patients With Advanced Biliary Tract Cancer | unknown | Phase 2 | 30 | Dai, GuanghaiOTHER | 1 | Jul 22, 2019 | clinicaltrials |
| NCT03185988 | Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System | unknown | Phase 2 | 100 | Shen LinOTHER | 1 | Jul 19, 2019 | clinicaltrials |
| NCT02955771 | Efficacy and Safety Study of PDT Using Deuteporfin for Unresectable Advanced Perihilar Cholangiocarcinoma | terminated | Phase 2 | 7 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jul 17, 2019 | clinicaltrials |
| NCT03150615 | Enteral Nutrition After Pancreaticoduodenectomy | completed | N/A | 120 | Nanjing Medical UniversityOTHER | 1 | Jul 12, 2019 | clinicaltrials |
| NCT04014478 | A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain | unknown | N/A | 110 | Shanghai Golden Leaf MedTec Co. LtdINDUSTRY | 0 | Jul 10, 2019 | clinicaltrials |
| NCT04004234 | A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTC | unknown | Phase 1 / Phase 2 | 20 | Chinese PLA General HospitalOTHER | 1 | Jul 9, 2019 | clinicaltrials |
| NCT01470443 | Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma | unknown | Phase 3 | 240 | Samsung Medical CenterOTHER | 1 | May 21, 2019 | clinicaltrials |
| NCT02350686 | XELOX in Advanced Biliary Tract Carcinoma After Failure of Gemcitabine-based Chemotherapy | unknown | Phase 2 | 67 | Samsung Medical CenterOTHER | 1 | May 20, 2019 | clinicaltrials |
| NCT01766219 | CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery | completed | Phase 1 / Phase 2 | 17 | Wake Forest University Health SciencesOTHER | 1 | May 15, 2019 | clinicaltrials |
| NCT02000999 | Diagnosis of Bile Duct Strictures | completed | — | 110 | Washington University School of MedicineOTHER | 1 | May 13, 2019 | clinicaltrials |
Data updated 23 days agoSource updated May 19, 2020source: clinicaltrials