Clinical trial · Interventional
Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain Control
A Randomized Controlled Trial of Intraoperative Chemical Splanchnicectomy for Patients With Resected Pancreatobiliary Malignancies
NCT02002806CI-TRIAL-00040103completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a randomized study of surgery plus chemical nerve block versus surgery plus placebo for pain control in subjects with pancreatic cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Biliary Tract Cancer | Malignant Biliary Tract Neoplasm | ALIAS | 0.90 |
| Pancreas Cancer | Pancreatic Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Alcohol Injection | Other | — | UNRESOLVED |
| Placebo Injection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Alcohol Injection
- description
- Celiac plexus neurolysis by alcohol injection One time administration during surgery 20 ml of alcohol injection on each side of aorta at level of celiac axis
- interventionNames
- Other: Alcohol Injection
- type
- PLACEBO_COMPARATOR
- label
- Placebo Injection
- description
- Celiac plexus injection - placebo injection
- interventionNames
- Other: Placebo Injection
Primary outcomes (1)
- measure
- Pain Control
- timeFrame
- 12 Months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: This study will be offered to all patients scheduled to undergo open or laparoscopic operative resection of a presumed pancreatic (any location; i.e., head, body, or tail) or distal biliary tract cancer. * Physiologic suitability for major abdominal surgery * Aged 18 years and older * Written informed consent * Ability to understand and comply with study guidelines. Exclusion Criteria: * Pregnancy * Previous, preoperative celiac nerve block * Neoadjuvant chemotherapy or radiation therapy * Incomplete tumor resection (R2 resection, grossly positive resection margin) * Presumed ampullary or duodenal cancer based on preoperative work-up or intraoperative findings * Benign tumors, neuroendocrine tumors, soft tissue tumors based on preoperative work-up or intraoperative findings * Known metastatic disease
References
Publications (0)
Data not yet available
No reference posted for this study.