Subtype
Malignant Anorectal Neoplasm
CI-CAN-00005864Explore in graph →
452 active trials1 approved drugs6 evidence items
- NCIt
- C215225
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Subtype
CI-CAN-00005864Explore in graph →
Clinical trials
1,783 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (174)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04296240 | Induction Chemotherapy for MRF-negative, Moderate-risk, Resectable Middle and Low Rectal Cancer | unknown | Phase 2 | 119 | Peking University Cancer Hospital & InstituteOTHER | 1 | Mar 5, 2020 | clinicaltrials |
| NCT03022734 | Short Course Radiotherapy, Unresectable Rectal Cancer, Liver Metastasis | unknown | Phase 2 | 40 | Yonsei UniversityOTHER | 1 | Jan 13, 2020 | clinicaltrials |
| NCT04170530 |
| Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer |
| unknown |
| Phase 2 |
| 51 |
| First Affiliated Hospital of Zhejiang UniversityOTHER |
| 1 |
| Nov 20, 2019 |
| clinicaltrials |
| NCT01923987 | Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis | unknown | Phase 2 | 39 | Korea Cancer Center HospitalOTHER | 1 | Sep 20, 2019 | clinicaltrials |
| NCT03944252 | Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)(CARACAS) | unknown | Phase 2 | 54 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Jul 26, 2019 | clinicaltrials |
| NCT01047969 | Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy | unknown | Phase 2 | 99 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 13, 2019 | clinicaltrials |
| NCT02648386 | Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery | unknown | Phase 1 / Phase 2 | 34 | Chinese Academy of SciencesOTHER_GOV | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03040180 | Endoscopic Assisted Electrochemotherapy in Addition to Neoadjuvant Treatment of Locally Advanced Rectal Cancer(nECT) | unknown | Phase 2 | 40 | Zealand University HospitalOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03702985 | Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer | unknown | Phase 2 | 160 | Fudan UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT01037049 | Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks | unknown | Phase 2 | 237 | Royal Marsden NHS Foundation TrustOTHER | 4 | Sep 17, 2018 | clinicaltrials |
| NCT02919878 | Neo-adjuvant Chemoradiotherapy Using Infusional Gemcitabine Followed by Surgery for Locally Advanced Rectal Cancer | unknown | Phase 2 | 25 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT03607643 | A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies | unknown | Phase 1 / Phase 2 | 160 | Leaf Vertical Inc.INDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT03561142 | Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy.(CAO/ARO/AIO-16) | unknown | Phase 2 | 94 | University Hospital TuebingenOTHER | 1 | Jun 19, 2018 | clinicaltrials |
| NCT03381352 | Study of IMRT Radiotherapy Concurrent Chemothrerapy for Anal Cancer | unknown | Phase 2 | 27 | Chinese Academy of Medical SciencesOTHER | 1 | Jan 30, 2018 | clinicaltrials |
| NCT02942563 | Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | unknown | Phase 2 | 100 | RenJi HospitalOTHER | 1 | Jan 3, 2018 | clinicaltrials |
| NCT01431599 | Short-course Preoperative Chemoradiotherapy for Rectal Cancer(KROG 11-02) | unknown | Phase 2 | 80 | Jong Hoon LeeOTHER | 1 | Oct 10, 2017 | clinicaltrials |
| NCT03302858 | A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand | unknown | Phase 2 | 70 | Stephen E. GoldstoneOTHER | 1 | Oct 5, 2017 | clinicaltrials |
| NCT03280407 | NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer(NEOLAR) | unknown | Phase 2 | 124 | Zealand University HospitalOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT01716949 | Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer(HyRec) | unknown | Phase 1 / Phase 2 | 59 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT02941562 | A Prospective Phase II Randomized Clinical Trial of Preoperative Chemotherapy Combined With Short-course Radiotherapy Versus Conventional Neo-adjuvant Therapy for Locally Advanced Rectal Cancer Implemented by MDT | unknown | Phase 2 | 150 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 0 | Oct 24, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT02830633 | Trial to Evaluate Laparoscopy-assisted Nerve-preserved Total Mesorectal Excision (LNTME) Versus Open TME for Rectal Cancer | unknown | Phase 2 | 80 | Anhui Medical UniversityOTHER | 0 | Jul 13, 2016 | clinicaltrials |
| NCT00754078 | A Phase II Study to Assess Acute Toxicity and Quality of Life of Patients With Carcinoma of the Anal Canal Receiving Chemotherapy and Radiation Using Helical Tomotherapy | unknown | Phase 2 | 58 | AHS Cancer Control AlbertaOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT02603302 | Radiation Dose Escalation in Locally Advanced Rectal Cancer(RaDE) | unknown | Phase 2 | 48 | University of BrasiliaOTHER | 1 | Jun 14, 2016 | clinicaltrials |
| NCT01257360 | Panitumumab in Combination With Radiotherapy in Patients With Locally Advanced RAS Wildtype Rectal Cancer (Clinical Stages II and III)(NEO-RIT) | unknown | Phase 2 | 59 | WiSP Wissenschaftlicher Service Pharma GmbHOTHER | 1 | Jan 13, 2016 | clinicaltrials |
| NCT02051868 | International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel(InterAACT) | unknown | Phase 2 | 80 | Royal Marsden NHS Foundation TrustOTHER | 3 | Nov 4, 2015 | clinicaltrials |
| NCT02510378 | Short Course Radiotherapy Combined With Chemotherapy in Stage IV Rectal Cancer With Resectable Liver Metastases | unknown | Phase 2 | 47 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 29, 2015 | clinicaltrials |
| NCT02490709 | Local Excision of Clinical T3 Rectal Adenocarcinoma Showing Major Response(ycT0-1) After Neoadjuvant Chemoradiotherapy | unknown | Phase 2 | 86 | National Cancer Center, KoreaOTHER_GOV | 1 | Jul 7, 2015 | clinicaltrials |
| NCT02488707 | Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR).(MISS-TRICR) | unknown | Phase 2 | 250 | Mansoura UniversityOTHER | 1 | Jul 2, 2015 | clinicaltrials |
| NCT01818973 | Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer | unknown | Phase 2 | 45 | Sun Yat-sen UniversityOTHER | 1 | Jun 8, 2015 | clinicaltrials |
| NCT01211210 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer(FOWARC) | unknown | Phase 2 / Phase 3 | 495 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2015 | clinicaltrials |
| NCT02195141 | Trial of Using SIB-IMRT in Preoperative Radiotherapy for Locally Advanced Rectum Cancer | unknown | Phase 2 | 104 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 4, 2015 | clinicaltrials |
| NCT02288078 | Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402) | unknown | Phase 2 | 74 | Clinical Research Support Center KyushOTHER | 1 | Nov 13, 2014 | clinicaltrials |
| NCT02280070 | RP II Study of SOX vs mFOLFOX6 in Patients With Resectable Rectal Cancer (KSCC1301). | unknown | Phase 2 | 110 | Clinical Research Support Center KyushOTHER | 1 | Oct 31, 2014 | clinicaltrials |
| NCT02268006 | IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment(BISER) | unknown | Phase 2 | 50 | Institute of Oncology LjubljanaOTHER | 1 | Oct 20, 2014 | clinicaltrials |
| NCT02177084 | Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surgery | unknown | Phase 2 | 12 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Jun 27, 2014 | clinicaltrials |
| NCT00795301 | A Study of Radiotherapy in Rectal Cancer Using Oxaliplatin, Capecitabine With or Without Cetuximab | unknown | Phase 2 | 74 | National University Hospital, SingaporeOTHER | 1 | Jan 14, 2014 | clinicaltrials |
| NCT02022852 | Neoadjuvant Sequential Therapy in Locally Advanced Mid/Low Rectal Cancer | unknown | Phase 2 | 80 | Harbin Medical UniversityOTHER | 1 | Dec 30, 2013 | clinicaltrials |
| NCT01586117 | A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity | unknown | Phase 2 | 40 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 15, 2013 | clinicaltrials |
| NCT01899118 | Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer | unknown | Phase 2 | 50 | Zhejiang Cancer HospitalOTHER | 1 | Jul 15, 2013 | clinicaltrials |
| NCT01227239 | Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting | unknown | Phase 1 / Phase 2 | 45 | Japan Clinical Cancer Research OrganizationOTHER | 1 | Nov 27, 2012 | clinicaltrials |
| NCT01237665 | IXO (Irinotecan, Xeloda, Oxaliplatin) in Rectal Cancer(IXOr) | unknown | Phase 2 | 15 | Ottawa Hospital Research InstituteOTHER | 1 | Oct 15, 2012 | clinicaltrials |
| NCT00689702 | Cetuximab (Erbitux®), Capecitabine and Radiotherapy in Neoadjuvant Treatment of Patients With Rectal Cancer(XERT) | unknown | Phase 2 | 43 | Institute of Oncology LjubljanaOTHER | 1 | Mar 26, 2012 | clinicaltrials |
| NCT00842686 | Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study(CRAB) | unknown | Phase 2 | 60 | Institute of Oncology LjubljanaOTHER | 1 | Mar 26, 2012 | clinicaltrials |
| NCT01064999 | A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer | unknown | Phase 2 / Phase 3 | 240 | Fudan UniversityOTHER | 1 | Mar 14, 2012 | clinicaltrials |
| NCT00122291 | A Study of Preoperative Radiation Therapy and Capecitabine in Locally Advanced Rectal Cancer | unknown | Phase 2 | 66 | Alberta Health servicesOTHER | 1 | Jan 19, 2012 | clinicaltrials |
| NCT01489332 | Induction Chemotherapy,Radiochemotherapy, Consolidation Chemotherapy in Preoperative Treatment of Rectal Cancer | unknown | Phase 2 | 60 | Institute of Oncology LjubljanaOTHER | 1 | Dec 9, 2011 | clinicaltrials |
| NCT00635466 | Phase II Trial to Evaluate Laparoscopic Surgery for Stage 0/I Rectal Carcinoma(Lap RC) | unknown | Phase 2 | 495 | Japan Society of Laparoscopic Colorectal SurgeryNETWORK | 1 | Jun 16, 2011 | clinicaltrials |
| NCT01340508 | Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer | unknown | Phase 2 | 63 | National University Hospital, SingaporeOTHER | 1 | Apr 22, 2011 | clinicaltrials |
Data updated 22 days agoSource updated Mar 5, 2020source: clinicaltrials