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Genomics
31 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
961 cases with simple somatic mutation data · 995 cases total · Data Release 46.0 · mapped to Multiple Myeloma CURATED_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | IGHV2-70 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 437 |
| 961 |
| 45.5% |
| gdc |
| 2 | IGLV3-1 | Ssm | 364 | 961 | 37.9% | gdc |
| 3 | IGHV2-70D | Ssm | 238 | 961 | 24.8% | gdc |
| 4 | KRAS | Ssm | 227 | 961 | 23.6% | gdc |
| 5 | BCL7A | Ssm | 212 | 961 | 22.1% | gdc |
| 6 | IGLL5 | Ssm | 211 | 961 | 22% | gdc |
| 7 | LTB | Ssm | 186 | 961 | 19.4% | gdc |
| 8 | NRAS | Ssm | 183 | 961 | 19% | gdc |
| 9 | TTN | Ssm | 181 | 961 | 18.8% | gdc |
| 10 | MIR5195 | Ssm | 143 | 961 | 14.9% | gdc |
| 12 | IGHV1-69D | Ssm | 115 | 961 | 12% | gdc |
| 11 | TENT5C | Ssm | 115 | 961 | 12% | gdc |
| 13 | MUC16 | Ssm | 102 | 961 | 10.6% | gdc |
| 14 | BMP6 | Ssm | 100 | 961 | 10.4% | gdc |
| 15 | IGKV4-1 | Ssm | 99 | 961 | 10.3% | gdc |
| 16 | DIS3 | Ssm | 97 | 961 | 10.1% | gdc |
| 17 | TMSB4X | Ssm | 97 | 961 | 10.1% | gdc |
| 18 | TRAF3 | Ssm | 86 | 961 | 8.9% | gdc |
| 20 | FAT4 | Ssm | 84 | 961 | 8.7% | gdc |
| 19 | CSMD3 | Ssm | 84 | 961 | 8.7% | gdc |
| 21 | RYR2 | Ssm | 81 | 961 | 8.4% | gdc |
| 22 | PCDH15 | Ssm | 79 | 961 | 8.2% | gdc |
| 23 | FAT3 | Ssm | 78 | 961 | 8.1% | gdc |
| 24 | PCLO | Ssm | 76 | 961 | 7.9% | gdc |
| 25 | NRXN1 | Ssm | 75 | 961 | 7.8% | gdc |
| 26 | LRP1B | Ssm | 73 | 961 | 7.6% | gdc |
| 28 | IGLV4-60 | Ssm | 71 | 961 | 7.4% | gdc |
| 27 | USH2A | Ssm | 71 | 961 | 7.4% | gdc |
| 29 | DUSP2 | Ssm | 70 | 961 | 7.3% | gdc |
| 30 | BRAF | Ssm | 69 | 961 | 7.2% | gdc |
Data updated 22 days agoSource updated Data Release 46.0