Lung Squamous Cell Carcinoma — Genomics · CancerIndex

Lung Squamous Cell Carcinoma — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

7 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Lung Squamous Cell Carcinoma TCGA-LUSCTCGA

504 cases with simple somatic mutation data · 504 cases total · Data Release 46.0 · mapped to Lung Squamous Cell Carcinoma ONTOLOGY_EXACT

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	453	504	89.9%	gdc
6	ATP11B	Ssm	444	504	88.1%	gdc
2	DVL3	Ssm	444	504	88.1%	gdc
4	ABCC5	Ssm	444	504	88.1%	gdc
3	KLHL6	Ssm	444	504	88.1%	gdc
5	EEF1AKMT4-ECE2	Ssm	444	504	88.1%	gdc
7	CCDC39	Ssm	444	504	88.1%	gdc
8	EPHB3	Ssm

Data updated 22 days agoSource updated Data Release 46.0

Lung Squamous Cell Carcinoma (CPTAC, Cell 2021) lusc_cptac_2021CPTAC

108 cases with simple somatic mutation data · 80 cases total · 2026-01-16 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53

Lung Squamous Cell Carcinoma (CPTAC GDC, 2025) lusc_cptac_gdcCPTAC GDC

110 cases with simple somatic mutation data · 110 cases total · 2026-01-14 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	101

Lung Squamous Cell Carcinoma (TCGA, Firehose Legacy) lusc_tcgaTCGA

178 cases with simple somatic mutation data · 511 cases total · 2026-01-07 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	145

Lung Squamous Cell Carcinoma (TCGA GDC, 2025) lusc_tcga_gdcTCGA GDC

484 cases with simple somatic mutation data · 503 cases total · 2026-01-13 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	408

Lung Squamous Cell Carcinoma (TCGA, Nature 2012) lusc_tcga_pubTCGA

178 cases with simple somatic mutation data · 178 cases total · 2026-02-19 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53

Lung Squamous Cell Carcinoma (TCGA, PanCancer Atlas) lusc_tcga_pan_can_atlas_2018TCGA

484 cases with simple somatic mutation data · 487 cases total · 2026-06-04 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.