Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,846 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,846 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05736731 | A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression(EVEREST-1) | active not recruiting | Phase 1 / Phase 2 | 160 | A2 Biotherapeutics Inc.INDUSTRY | 1 | Apr 25, 2025 | clinicaltrials |
| NCT03428477 | EPA for Metastasis Trial 2(EMT2) | active not recruiting | Phase 3 | 418 | Mark A Hull, PhD FRCPOTHER | 1 |
| Apr 18, 2025 |
| clinicaltrials |
| NCT03908788 | Detection of the Emergence of RAS (Rat Sarcoma Viral Oncogene Homolog) Mutations in Circulating DNA (Deoxyribonucleic Acid) in Patients With mCRC (Metastatic Colorectal Cancer) During Treatment With Anti-EGFR (Epidermal Growth Factor Receptor) Therapy(EmutRAS) | active not recruiting | N/A | 130 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT06920082 | Progressive Muscle Relaxation Exercises on Sleep, Fatigue and Pain in Pancreatic and Colon Cancer Patients | active not recruiting | N/A | 60 | Istanbul Sabahattin Zaim UniversityOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT06056804 | Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer | active not recruiting | Phase 2 | 20 | Beijing Friendship HospitalOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT06443203 | Multimodal Prehabilitation in Colorectal Cancer Patients | active not recruiting | N/A | 112 | University Hospital of FerraraOTHER | 1 | Mar 30, 2025 | clinicaltrials |
| NCT04749862 | Cancer Surveillance and Support(CANVAS) | active not recruiting | — | 565 | University of LeedsOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT03200834 | Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON) | active not recruiting | N/A | 239 | G.V. Bondar Republican Cancer CenterOTHER | 1 | Mar 26, 2025 | clinicaltrials |
| NCT01937780 | Anal Cancer Radiotherapy Study(ANCARAD) | active not recruiting | — | 75 | Oslo University HospitalOTHER | 1 | Mar 21, 2025 | clinicaltrials |
| NCT04802876 | Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors(ACROPOLI) | active not recruiting | Phase 2 | 184 | SOLTI Breast Cancer Research GroupOTHER | 1 | Mar 21, 2025 | clinicaltrials |
| NCT05623787 | Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms(DWI-HighRisk) | active not recruiting | N/A | 30 | Laval UniversityOTHER | 1 | Mar 20, 2025 | clinicaltrials |
| NCT06886022 | Diagnosis, Treatment, and Prevention of Colorectal Cancer Amid Abnormal Lipid Metabolism | active not recruiting | — | 1,000 | Tianjin Union Medical CenterOTHER | 0 | Mar 20, 2025 | clinicaltrials |
| NCT04585035 | Study to Evaluate D-1553 in Subjects With Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 180 | InventisBio Co., LtdINDUSTRY | 4 | Mar 18, 2025 | clinicaltrials |
| NCT04612309 | Retrospective Study on the Use of Immunotherapy in Patients With MSI-H Metastatic Colorectal Cancer(C-MSI) | active not recruiting | — | 100 | Gruppo Oncologico Italiano di Ricerca ClinicaOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT05765214 | Impact of Colorectal Cancer and Nutrition Education Program Among Minority Patients With Type 2 Diabetes | active not recruiting | N/A | 120 | Charles Drew University of Medicine and ScienceOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06853769 | Neoadjuvant Therapy for Locally Advanced Rectal Cancer(LARC-nCR01) | active not recruiting | Early Phase 1 | 48 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Mar 3, 2025 | clinicaltrials |
| NCT06852495 | the Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes | active not recruiting | — | 200 | Dong PengOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT03795311 | Evaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in Patients With Colorectal Cancer (FOLFIRINOX 3)(FOLFIRINOX3) | active not recruiting | Phase 1 / Phase 2 | 32 | Centre Georges Francois LeclercOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT03255434 | LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy(LEANOX) | active not recruiting | Phase 2 | 160 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT04013152 | Clinical Database of Colorectal Robotic Surgery(ROBOT CR) | active not recruiting | — | 1,800 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 12, 2025 | clinicaltrials |
| NCT04224779 | Liquid Biopsies and IMAging for Improved Cancer Care(LIMA) | active not recruiting | N/A | 16 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 12, 2025 | clinicaltrials |
| NCT04046445 | Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer(KISIMA-01) | active not recruiting | Phase 1 | 96 | Amal TherapeuticsINDUSTRY | 4 | Jan 29, 2025 | clinicaltrials |
| NCT04313114 | The PRIME-CRC Trial to Promote CRC Screening in Rural Communities | active not recruiting | N/A | 804 | Louisiana State University Health Sciences Center ShreveportOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT04440735 | A Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 125 | Kahr MedicalINDUSTRY | 1 | Jan 9, 2025 | clinicaltrials |
| NCT05688280 | Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS(INJECTABL-1) | active not recruiting | Phase 1 / Phase 2 | 42 | Immunophotonics, Inc.INDUSTRY | 5 | Jan 8, 2025 | clinicaltrials |
| NCT03368963 | TAS102 in Combination With NAL-IRI in Advanced GI Cancers | active not recruiting | Phase 1 / Phase 2 | 64 | Emory UniversityOTHER | 1 | Jan 7, 2025 | clinicaltrials |
| NCT02843191 | Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy | active not recruiting | Phase 3 | 358 | Kyung Hee University Hospital at GangdongOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT04719988 | Anti-PD-1 and mDCF Followed by Chemoradiotherapy in Patients With Stage III Squamous Cell Anal Carcinoma.(INTERACT-ION) | active not recruiting | Phase 2 | 55 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Dec 20, 2024 | clinicaltrials |
| NCT05121038 | CEND-1 in Combination with Neoadjuvant FOLFIRINOX with or Without Panitumumab(CENDIFOX) | active not recruiting | Phase 1 / Phase 2 | 50 | Anup KasiOTHER | 1 | Dec 17, 2024 | clinicaltrials |
| NCT01531595 | Study of Bevacizumab in Combination with Alternating XELIRI and XELOX in Metastatic Colorectal Cancer(AXOAXI) | active not recruiting | Phase 2 | 100 | Pia OsterlundOTHER | 1 | Dec 12, 2024 | clinicaltrials |
| NCT06465914 | A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males | active not recruiting | Phase 3 | 9,000 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Dec 12, 2024 | clinicaltrials |
| NCT06730035 | PRediction of Outcomes and PERsonalized Radiotherapy by Biomarkers and Functional Imaging | active not recruiting | N/A | 30 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Dec 12, 2024 | clinicaltrials |
| NCT06709144 | Borderline of CME/D3 Dissection for Local Advanced Right-sided Colon Cancer(BLARCC) | active not recruiting | Phase 3 | 896 | Haixing Ju, MDOTHER | 1 | Nov 29, 2024 | clinicaltrials |
| NCT05969899 | Liposomal Irinotecan Based FOLFIRI With Bevacizumab in First-line Treatment of Advanced Colorectal Cancer | active not recruiting | Phase 2 | 50 | Fudan UniversityOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT05457244 | Safety and Performance of the da Vinci SP® Surgical System in Colorectal Procedures | active not recruiting | N/A | 30 | Chang Gung Memorial HospitalOTHER | 1 | Nov 20, 2024 | clinicaltrials |
| NCT03845166 | A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors(STELLAR-001) | active not recruiting | Phase 1 | 325 | ExelixisINDUSTRY | 10 | Nov 19, 2024 | clinicaltrials |
| NCT04294264 | TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer | active not recruiting | Phase 2 | 50 | Rutgers, The State University of New JerseyOTHER | 1 | Nov 18, 2024 | clinicaltrials |
| NCT04898504 | HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden.(EXCALIBUR1+2) | active not recruiting | Phase 2 | 45 | Oslo University HospitalOTHER | 1 | Nov 7, 2024 | clinicaltrials |
| NCT05674422 | GEMCAD-REVEAL STUDY - Circulating Tumor DNA as a Predictor of Relapse in Patients With Locally Advanced Rectal Cancer.(REVEAL) | active not recruiting | — | 120 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Oct 31, 2024 | clinicaltrials |
| NCT06662643 | A Clinical Trial Comparing Staged Turnbull-Cutait Pull-through Anastomosis With Direct Anastomosis Plus Prophylactic Ileostomy in the Treatment of Low Rectal Cancer After Internal Sphincter Resection(STAR-TAR) | active not recruiting | N/A | 110 | Zhongnan HospitalOTHER | 1 | Oct 29, 2024 | clinicaltrials |
| NCT04161092 | The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases(SOULMATE) | active not recruiting | N/A | 45 | Vastra Gotaland RegionOTHER_GOV | 1 | Oct 28, 2024 | clinicaltrials |
| NCT03635021 | Study to Evaluate the Efficacy of FOLFOX + Panitumumab Followed by FOLFIRI + Bevacizumab (Sequence 1) Versus FOLFOX + Bevacizumab Followed by FOLFIRI + Panitumumab (Sequence 2) in Untreated Patients With Wild-type RAS Metastatic, Primary Left-sided, Unresectable Colorectal Cancer(CR-SEQUENCE) | active not recruiting | Phase 3 | 419 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Oct 21, 2024 | clinicaltrials |
| NCT06643429 | Impact of Environmental Factors and Metabolomics on Colorectal Cancer. | active not recruiting | — | 700 | Dong PengOTHER | 1 | Oct 16, 2024 | clinicaltrials |
| NCT04584008 | Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics(VISIONARY) | active not recruiting | N/A | 600 | Peking UniversityOTHER | 1 | Oct 15, 2024 | clinicaltrials |
| NCT05620134 | Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer | active not recruiting | Phase 1 / Phase 2 | 263 | Salubris Biotherapeutics IncINDUSTRY | 2 | Oct 15, 2024 | clinicaltrials |
| NCT05215574 | Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors | active not recruiting | Phase 1 | 130 | NGM Biopharmaceuticals, IncINDUSTRY | 1 | Oct 10, 2024 | clinicaltrials |
| NCT04117945 | Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer | active not recruiting | Phase 2 | 22 | Academic and Community Cancer Research UnitedOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT06614660 | Metabolism Imaging-genomics for Predicting the Surgical Outcomes of Colorectal Cancer | active not recruiting | — | 800 | First Affiliated Hospital of Chongqing Medical UniversityOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT06614699 | Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Colorectal Cancer Patients | active not recruiting | — | 8,000 | First Affiliated Hospital of Chongqing Medical UniversityOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT05656326 | Follow-up After Surgery for Colorectal Cancer(FUTURE-primary) | active not recruiting | — | 200 | Erasmus Medical CenterOTHER | 1 | Sep 25, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Apr 25, 2025source: clinicaltrials