Clinical trial · Observational
the Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes
A Study of Colorectal Cancer Development and Prognosis Based on Environmental Factors and Macrogenomes
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to investigate the effects of environmental factors, such as air pollution, on the occurrence, development and prognosis of colorectal cancer; to identify metabolic markers specific to colorectal cancer patients, which will provide a basis for early diagnosis, early intervention and individualized treatment; and to comprehensively understand the mechanism of the occurrence and development of colorectal cancer by integrating the data of environmental factors and the macro-genome, and to develop new predictive and therapeutic strategies.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- the colorectal cancer group
- description
- patients diagnosed with colorectal cancer
- label
- the control group
- description
- Healthy individuals with no history of malignant tumor
Primary outcomes (1)
- measure
- prognosis
- timeFrame
- From date of diagnosis until the date of death from any cause or or loss to follow-up, whichever came first, assessed up to 60 months
- description
- Overall survival (OS), from date of diagnosis until the date of death from any cause or or loss to follow-up, whichever came first.
Secondary outcomes (1)
- measure
- Macrogenomic differences
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥18 years old; * Patients diagnosed with colorectal cancer by pathologic biopsy before surgery; * Patients did not undergo chemotherapy, radiotherapy, targeted and immunotherapy, etc. before enrollment; * Willing to participate in the study and sign an informed consent form. Complete clinical data. Exclusion Criteria: * Concurrent primary malignant tumor other than colorectal cancer; * Patients with severe cardiopulmonary insufficiency or other systemic diseases that affect the choice of treatment plan; * Inappropriate for enrollment as assessed by the investigator; * Incomplete clinical data.
References
Publications (0)
Data not yet available