Clinical trial · Interventional
Borderline of CME/D3 Dissection for Local Advanced Right-sided Colon Cancer
Borderline of CME/D3 Dissection for Local Advanced Right-sided Colon Cancer(BLARCC): a Prospective, Multicenter Randomized Control Clinical Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study was conducted on patients with advanced right-sided colon cancer, and the clinical pathological and prognostic data of the patients were compared between the two groups of patients who were randomly divided into those undergoing SMV and SMA left resection, with the aim of resolving the controversy over the left resection boundary of CME/D3 lymph node dissection through this study, and to clarify whether SMA left resection is superior to SMV left resection.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| SMA lymph node dissection | Procedure | — | UNRESOLVED |
| SMV lymph node dissection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group SMA
- description
- The lymph node dissection boundary is on the left side of the superior mesenteric artery (SMA).
- interventionNames
- Procedure: SMA lymph node dissection
- type
- ACTIVE_COMPARATOR
- label
- Group SMV
- description
- The lymph node dissection boundary is on the left side of the superior mesenteric vein (SMV)
- interventionNames
- Procedure: SMV lymph node dissection
Primary outcomes (1)
- measure
- 3 year DFS
- timeFrame
- 3 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 78 Years
Show eligibility criteria text
Inclusion Criteria: * right side colon cancer(The primary lesion is located in the ileocecal region, ascending colon, hepatic flexure of colon, or proximal transverse colon) * T3-4 and/or N1-2M0 * Colonoscopy and pathological biopsy confirmed colon adenocarcinoma Exclusion Criteria: * T1-2N0M0 * Cannot undergo curative resection * Simultaneous multiple primary colorectal cancer or other diseases requiring segmental resection * Distant metastasis * Tumor invades surrounding organs, requiring joint organ resection * Emergency surgery is required for complications such as intestinal obstruction, perforation, and bleeding * Patients who have received neoadjuvant therapy before surgery * Pregnant or lactating women * Patients who are not suitable or unable to tolerate surgery
References
Publications (0)
Data not yet available