Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07134218 | Neoadjuvant Chemoradiotherapy Combined With Immunotherapy and Anti-angiogenesis in Treating Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 / Phase 3 | 180 | Changhai HospitalOTHER | 1 | Aug 21, 2025 | clinicaltrials |
| NCT07134296 | Magnetic Resonance Imaging (MRI)-Guided Rectal Cancer Preservation Program | not yet recruiting | N/A | 32 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 0 | Aug 21, 2025 |
| NCT07132008 | Neoadjuvant CAPOX Plus Tislelizumab vs CAPOX in MSS High-Risk Locally Advanced Colon Cancer | not yet recruiting | Phase 3 | 94 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Aug 20, 2025 | clinicaltrials |
| NCT07124884 | 5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Patients Non-eligible for a Doublet/Triplet Chemotherapy With Advanced Unresectab(COLOSOTO) | not yet recruiting | Phase 2 | 300 | Federation Francophone de Cancerologie DigestiveOTHER | 4 | Aug 15, 2025 | clinicaltrials |
| NCT07123441 | A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer | not yet recruiting | Phase 2 | 300 | Sanjun CaiOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT07025850 | Efficacy Study of Digoxin Combined With Serplulimab and Chemotherapy in First-Line Treatment of MSS Advanced Colorectal Cancer | not yet recruiting | Phase 1 / Phase 2 | 20 | Fudan UniversityOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT07099924 | Rectus Sheath Catheters Following Midline Laparotomy | not yet recruiting | N/A | 40 | Asklepios Kliniken Hamburg GmbHOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06839092 | Prophylactic PIPAC in Patients With High-risk Colorectal Cancer(PROPAC) | not yet recruiting | Phase 3 | 160 | Jeremy MeyerOTHER | 0 | Jul 30, 2025 | clinicaltrials |
| NCT07090304 | China Colorectal Cancer Screening Trial 2 (C-Cost2) | not yet recruiting | N/A | 7,504 | Zhejiang UniversityOTHER | 0 | Jul 29, 2025 | clinicaltrials |
| NCT07088341 | Role of Programmed Death Ligand 1 in Colorectal Cancer(SPDL1) | not yet recruiting | — | 90 | Assiut UniversityOTHER | 0 | Jul 28, 2025 | clinicaltrials |
| NCT07074353 | Irinotecan Liposomes in Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer(CinClare-2) | not yet recruiting | Phase 3 | 360 | Zhejiang Cancer HospitalOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT07080411 | the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer | not yet recruiting | N/A | 49 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 0 | Jul 23, 2025 | clinicaltrials |
| NCT07071844 | BETWEEN: Biweekly Bevacizumab + Trifluridine/Tipiracil to Reduce Grade 3-4 Neutropenia in mCRC Patients(BETWEEN) | not yet recruiting | Phase 2 | 162 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jul 17, 2025 | clinicaltrials |
| NCT06710860 | ScreenTalk to Improve Colorectal Cancer Screening Uptake Among First-degree Relatives of Patients: a Study Protocol | not yet recruiting | N/A | 314 | Sun Yat-sen UniversityOTHER | 1 | Jul 15, 2025 | clinicaltrials |
| NCT07059949 | Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer(Union-mRC) | not yet recruiting | Phase 2 | 80 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 0 | Jul 11, 2025 | clinicaltrials |
| NCT07059338 | Dual EGFR/HER2 Blockade Combined With Irinotecan for the Treatment of HER2-Positive Metastatic Colorectal Cancer(HERBIC) | not yet recruiting | Phase 2 | 34 | Sun Yat-sen UniversityOTHER | 1 | Jul 10, 2025 | clinicaltrials |
| NCT07059442 | Screening for Anal Cancer and Precancer in Women With HIV (SANCA)(SANCA) | not yet recruiting | N/A | 1,000 | Karolinska InstitutetOTHER | 1 | Jul 10, 2025 | clinicaltrials |
| NCT07051785 | Fruquintinib vs Bevacizumab Combined With Irinotecan Liposome and Capecitabine as Second-Line Therapy for Advanced Metastatic Colorectal Cancer(ARK) | not yet recruiting | Phase 2 | 68 | Liu HuangOTHER | 0 | Jul 4, 2025 | clinicaltrials |
| NCT07045207 | Evaluating AI and Human Expert Decisions in Colorectal Cancer | not yet recruiting | — | 1,500 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 1, 2025 | clinicaltrials |
| NCT06823297 | Can Neoadjuvant Chemoradiotherapy be Ommited in Mid-rectal Cancer(CANO) | not yet recruiting | — | 436 | Turkish Society of Colon and Rectal SurgeryOTHER | 1 | Jun 27, 2025 | clinicaltrials |
| NCT07041515 | Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection Syndrome | not yet recruiting | N/A | 320 | National Cancer Center, KoreaOTHER_GOV | 0 | Jun 27, 2025 | clinicaltrials |
| NCT07035600 | Walking and Sitting Difficulties After Rectal Cancer Surgery(WASA) | not yet recruiting | N/A | 300 | Sahlgrenska University HospitalOTHER | 1 | Jun 25, 2025 | clinicaltrials |
| NCT07036185 | A Clinical Trail of KJ015 in Patients With HER2-Expressing Solid Tumors | not yet recruiting | Phase 1 | 66 | Shanghai Bao Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Jun 25, 2025 | clinicaltrials |
| NCT06902701 | Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia(ESTER) | not yet recruiting | — | 156 | Turkish Society of Colon and Rectal SurgeryOTHER | 1 | Jun 24, 2025 | clinicaltrials |
| NCT07031011 | PD-1-M1-NK Cells in the Treatment of Advanced Gastric or Colorectal Cancer | not yet recruiting | Phase 1 | 22 | jiuwei cuiOTHER | 1 | Jun 22, 2025 | clinicaltrials |
| NCT07029464 | Comparison of Short- and Long-term Outcomes Between Robotic and Laparoscopic Hemicolectomy of Right Colon Cancer : A Multicenter Propensity Score Matching Analysis | not yet recruiting | — | 4,000 | The First Affiliated Hospital of Nanchang UniversityOTHER | 0 | Jun 19, 2025 | clinicaltrials |
| NCT06057831 | PET/MRI in Rectal Cancer | not yet recruiting | Phase 2 | 40 | AHS Cancer Control AlbertaOTHER | 0 | Jun 18, 2025 | clinicaltrials |
| NCT07025239 | QL1706 Injection Plus Bevacizumab and XELOX vs Placebo Plus Bevacizumab and XELOX as First-Line Treatment of Unresectable Metastatic Colorectal Cancer | not yet recruiting | Phase 3 | 430 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Jun 17, 2025 | clinicaltrials |
| NCT07021950 | AK112 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI as Second-line Treatment of MSS/pMMR Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 130 | Sun Yat-sen UniversityOTHER | 0 | Jun 15, 2025 | clinicaltrials |
| NCT06646445 | Neoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.(PREMICES) | not yet recruiting | Phase 2 | 60 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jun 13, 2025 | clinicaltrials |
| NCT07007728 | Iparomlimab/Tuvonralimab Combined With Bevacizumab and CAPEOX as Conversion Therapy for Colorectal Cancer Liver Metastasis | not yet recruiting | Phase 2 | 54 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT07009145 | QL1706 Plus Bevacizumab for Unresectable or Metastatic MSI-H/dMMR CRC | not yet recruiting | Phase 2 | 22 | Qianfoshan HospitalOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT07003776 | Evaluation of Tumor Budding In Colorectal Adenocarcinoma | not yet recruiting | — | 50 | Sohag UniversityOTHER | 0 | Jun 4, 2025 | clinicaltrials |
| NCT07000305 | A Study of Cetuximabβ Combined With Envolimab and mFOLFOX6 in Subjects With Advanced Colorectal Cancer(SUPβORT) | not yet recruiting | Phase 2 | 42 | Tao ZhangOTHER | 1 | Jun 2, 2025 | clinicaltrials |
| NCT06999252 | Rimegepant Combined With PD-1 in Liver Metastasis Colorectal Cancer Patients | not yet recruiting | Phase 2 | 20 | Fudan UniversityOTHER | 1 | May 31, 2025 | clinicaltrials |
| NCT06991452 | Early Diagnosis and Recurrence Monitoring of Colorectal Cancer | not yet recruiting | — | 1,200 | Huashan HospitalOTHER | 1 | May 28, 2025 | clinicaltrials |
| NCT06973083 | Efficacy and Safety of Robot-assisted Endoscopic Submucosal Dissection for Colorectal Neoplasm | not yet recruiting | N/A | 104 | Shandong UniversityOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT06977373 | The Application Value of Spectral CT in the Accurate Staging of Colorectal Cancer | not yet recruiting | N/A | 150 | Yunnan Cancer HospitalOTHER | 1 | May 18, 2025 | clinicaltrials |
| NCT06971107 | Current Microsatellite Stability Results in Colon Cancer | not yet recruiting | — | 1,500 | Turkish Society of Colon and Rectal SurgeryOTHER | 1 | May 14, 2025 | clinicaltrials |
| NCT06963502 | A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Patients With Advanced Solid Tumors | not yet recruiting | Phase 1 | 762 | Jiangsu Hansoh Pharmaceutical Co., Ltd.INDUSTRY | 1 | May 9, 2025 | clinicaltrials |
| NCT06959693 | A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC) | not yet recruiting | Phase 2 / Phase 3 | 590 | Sun Yat-sen UniversityOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT06956976 | Preservation Vs. Dissection of No. 253 Lymph Nodes of Robotic Resection for Mid/Low Rectal Cancer(REAL2) | not yet recruiting | N/A | 1,596 | Fudan UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06944548 | Evaluation of the Effect of Adapted Physical Activity on the Modification of Lipid Metabolism During Chemotherapy for Metastatic COLorectal Cancer(APACOL) | not yet recruiting | Phase 2 | 54 | Centre Georges Francois LeclercOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT06948539 | To Evaluate the Tolerability and Pharmacokinetics of TQB2101 for Injection in Patients With Advanced Malignant Tumors | not yet recruiting | Phase 1 | 66 | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.INDUSTRY | 1 | Apr 29, 2025 | clinicaltrials |
| NCT06946004 | Normobaric Oxygen Therapy in Colorectal Cancer Patients(NBO-ONCO) | not yet recruiting | N/A | 254 | 4th Military Clinical Hospital with Polyclinic, PolandOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT06943690 | Safety and Efficacy Study of Single-port Robotic Versus Multi-port Robotic Radical Rectal Cancer Surgery | not yet recruiting | N/A | 212 | Ruijin HospitalOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06938490 | Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy(COLAP-D3) | not yet recruiting | N/A | 778 | the BELOOSTROV Clinic of High TechnologiesNETWORK | 1 | Apr 22, 2025 | clinicaltrials |
| NCT06935734 | Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions(CARE I) | not yet recruiting | N/A | 50 | Neptune MedicalINDUSTRY | 0 | Apr 20, 2025 | clinicaltrials |
| NCT06931873 | Neoadjuvant Radiochemotherapy Combined With QL1706 for Low Rectal Cancer | not yet recruiting | Early Phase 1 | 60 | Changhai HospitalOTHER | 0 | Apr 17, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Aug 21, 2025source: clinicaltrials