Clinical trial · Interventional
Rectus Sheath Catheters Following Midline Laparotomy
Bilateral Rectus Sheath Catheters Following Midline Laparotomy. A Randomized, Placebo-controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Rectus sheath catheters (RSC) are used for postoperative analgesia following midline laparotomies. Local anesthetics are applied to the posterior rectus sheath via the RSC. The target structures are the anterior cutaneous branches of the spinal nerves Th7-Th12. RSC can be used in particular if thoracic epidurals are contraindicated (compromised coagulation), technically unfeasible or refused by the patient. The study investigates placebo-controlled weather RSC have a significant additional analgesic effect in a multimodal analgesic concept. Primary outcome parameters are the maximum pain score, the Quality-of-Recovery-15-Score (QoR-15GE) and the opioid consumption (morphine equivalents) in the first 72h postoperatively.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Abdomen | — | UNRESOLVED | — |
| Colorectal Carcinoma | Colorectal Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Ileus | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ropivacaine 0.2% | Drug | — | UNRESOLVED |
| Saline 0.9% | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- ropivacaine 0.2%
- description
- 2x30 ml (bilateral) ropivacaine 0.2% every 8 hours
- interventionNames
- Drug: Ropivacaine 0.2%
- type
- PLACEBO_COMPARATOR
- label
- saline 0.9%
- description
- 2x30 ml (bilateral) saline 0.9% every 8 hours
- interventionNames
- Drug: Saline 0.9%
Primary outcomes (3)
- measure
- patient satisfaction
- timeFrame
- on first postoperative day
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Median laparotomy * Age over 18 years * Informed consent has been obtained Exclusion Criteria: * Local signs of inflammation * known allergy to local anesthetics used * chronic pain syndrome * drug addiction * post-operative ventilation that cannot be completed on the day of surgery * lack of consent or cooperation * pregnancy * participation in another medical study * sepsis
References
Publications (0)
Data not yet available