Clinical trial · Interventional
Screening for Anal Cancer and Precancer in Women With HIV (SANCA)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main aim of the SANCA study is to evaluate the feasibility, cost-effectiveness, and acceptability of implementing international anal cancer screening guidelines for women living with HIV in Sweden, integrating health economic and patient-centered approaches. Secondly the investigators wish to investigate the predictive potential of DNA methylation markers for the clinical progression of precancerous anal lesions in women with HIV, combining prospective molecular biology analysis with clinical data from registries.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anal Canal Cancer | Anal Canal Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| anal HPV screening | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Anal HPV testing
- description
- All included women will leave an anal HPV-self test
- interventionNames
- Diagnostic Test: anal HPV screening
Primary outcomes (1)
- measure
- Positive anal hrHPV test
- timeFrame
- at inclusion and through study completion, an average of 1 year
- description
- Number of participants with positive anal hrHPV test
Secondary outcomes (6)
- measure
- Low-grade (LSIL) and high-grade (HSIL) squamous intrepithelial lesions
- timeFrame
- at inclusion and through study completion, an average of one year
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Women (biological sex) with HIV * 45 years old or older * attending the out-patient HIV departments at Karolinska University Hospital in Stockholm, the South Hospital in Stockholm, and Sahlgrenska University Hospital in Gothenburg Exclusion Criteria: * Women who have had anal cancer * women who have had rectal amputation
References
Publications (0)
Data not yet available