Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03634501 | Clinical Study on Anti-tumor Effect Induced by Activated Primary Natural Killer(NK)Cells | unknown | Phase 1 / Phase 2 | 200 | Xuanwu Hospital, BeijingOTHER | 1 | Jan 11, 2019 | clinicaltrials |
| NCT03418558 | Study of Trastuzumab-emtansine in Patients With HER2-positive Metastatic Colorectal Cancer Progressing After Trastuzumab and Lapatinib.(RESCUE) | unknown | Phase 2 | 13 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Oct 31, 2018 |
| clinicaltrials |
| NCT03225937 | Evaluation of Trastuzumab in Combination With Lapatinib or Pertuzumab in Combination With Trastuzumab-Emtansine to Treat Patients With HER2-positive Metastatic Colorectal Cancer(HERACLES) | unknown | Phase 2 | 54 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Oct 30, 2018 | clinicaltrials |
| NCT03686254 | The Effects of RFA in Combination With Second-line Chemotherapy and Bevacizumab on Unresectable CRLM | unknown | Phase 2 / Phase 3 | 160 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Sep 26, 2018 | clinicaltrials |
| NCT01037049 | Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks | unknown | Phase 2 | 237 | Royal Marsden NHS Foundation TrustOTHER | 4 | Sep 17, 2018 | clinicaltrials |
| NCT02519582 | Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy(Nikolo) | unknown | Phase 2 | 37 | Charite University, Berlin, GermanyOTHER | 1 | Sep 12, 2018 | clinicaltrials |
| NCT03142282 | Consolidative Radiotherapy Plus Maintenance Chemotherapy for Metastatic Colorectal Cancer(MCRC-LC1) | unknown | Phase 2 | 200 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Sep 7, 2018 | clinicaltrials |
| NCT02450656 | Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer(M14AFS) | unknown | Phase 1 / Phase 2 | 320 | The Netherlands Cancer InstituteOTHER | 1 | Aug 27, 2018 | clinicaltrials |
| NCT02526836 | Complete Mesocolic Excision With Central Vessel Ligation Compared With Conventional Surgery for Colon Cancer | unknown | Phase 2 / Phase 3 | 40 | Mansoura UniversityOTHER | 2 | Aug 16, 2018 | clinicaltrials |
| NCT02919878 | Neo-adjuvant Chemoradiotherapy Using Infusional Gemcitabine Followed by Surgery for Locally Advanced Rectal Cancer | unknown | Phase 2 | 25 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT01949194 | Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover Biomarkers | unknown | Phase 2 | 48 | Gerald BatistOTHER | 1 | Aug 10, 2018 | clinicaltrials |
| NCT03545711 | Safety and Efficacy of Anlotinib in Combination With Irinotecan in Patients With Pretreated Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 42 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 6, 2018 | clinicaltrials |
| NCT03607643 | A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies | unknown | Phase 1 / Phase 2 | 160 | Leaf Vertical Inc.INDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT03601598 | A Trial of SHR-1210 in Combination With SHR6390 in Patients With Advanced CRC, NSCLC and HCC | unknown | Phase 1 / Phase 2 | 41 | Harbin Medical UniversityOTHER | 0 | Jul 26, 2018 | clinicaltrials |
| NCT03561142 | Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy.(CAO/ARO/AIO-16) | unknown | Phase 2 | 94 | University Hospital TuebingenOTHER | 1 | Jun 19, 2018 | clinicaltrials |
| NCT03511170 | XELOX and XELIRI Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer | unknown | Phase 2 | 66 | Harbin Medical UniversityOTHER | 1 | May 1, 2018 | clinicaltrials |
| NCT03511183 | XELOX+Bevacizumab and XELIRI + Bevacizumab Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer | unknown | Phase 2 | 66 | Harbin Medical UniversityOTHER | 1 | May 1, 2018 | clinicaltrials |
| NCT01196260 | Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III | unknown | Phase 2 / Phase 3 | 8,000 | State Key Laboratory of Cancer BiologyNETWORK | 1 | Feb 20, 2018 | clinicaltrials |
| NCT02296203 | Cetuximab Rechallenge in Irinotecan-pretreated mCRC, KRAS, NRAS and BRAF Wild-type Treated in 1st Line With Anti-EGFR Therapy (CRICKET).(CRICKET) | unknown | Phase 2 | 27 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Feb 15, 2018 | clinicaltrials |
| NCT03422835 | Robotic Assisted Transanal Total Mesorectal Excision Surgery for Rectal Cancer in Low Site | unknown | Phase 2 | 50 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 0 | Feb 6, 2018 | clinicaltrials |
| NCT03381352 | Study of IMRT Radiotherapy Concurrent Chemothrerapy for Anal Cancer | unknown | Phase 2 | 27 | Chinese Academy of Medical SciencesOTHER | 1 | Jan 30, 2018 | clinicaltrials |
| NCT03412994 | Clinical Study of Apatinib Combined With Second - Line Chemotherapy for Metastatic Colorectal Cancer | unknown | Phase 2 | 60 | Liqiang ZhongOTHER | 0 | Jan 29, 2018 | clinicaltrials |
| NCT03405272 | Safety and Efficacy of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Wild-type RAS and BRAF mCRC | unknown | Phase 2 | 110 | Sinocelltech Ltd.INDUSTRY | 1 | Jan 23, 2018 | clinicaltrials |
| NCT03403452 | Apatinib in the Treatment of Metastatic Colorectal Cancer | unknown | Phase 2 | 33 | Fudan UniversityOTHER | 1 | Jan 18, 2018 | clinicaltrials |
| NCT03093129 | Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer (NeoART-V)(NeoART-V) | unknown | Phase 2 | 200 | The 108 Military Central HospitalOTHER_GOV | 1 | Jan 9, 2018 | clinicaltrials |
| NCT02942563 | Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | unknown | Phase 2 | 100 | RenJi HospitalOTHER | 1 | Jan 3, 2018 | clinicaltrials |
| NCT03377842 | Apatinib Treatment as the Neoadjuvant Therapy in Advanced Colorectal Cancer | unknown | Phase 2 | 100 | Sichuan Provincial People's HospitalOTHER | 0 | Dec 19, 2017 | clinicaltrials |
| NCT03344614 | A Study of Apatinib in Combination With Raltitrexed Treatment in Patients With Advanced Colorectal Cancer | unknown | Phase 2 | 30 | Chinese PLA General HospitalOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT02625272 | A Novel Technique of HALS With CME and CVL for RCC | unknown | Phase 2 | 60 | West China HospitalOTHER | 1 | Nov 8, 2017 | clinicaltrials |
| NCT01348256 | Study With Dendritic Cell Immunotherapy in Resected Hepatic Metastasis of Colorectal Carcinoma | unknown | Phase 2 | 58 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 1 | Oct 24, 2017 | clinicaltrials |
| NCT02717923 | A Single Arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Maintenance Treatment With Capecitabine Plus Cetuximab in Metastatic Colorectal Cancer | unknown | Phase 2 | 50 | Huazhong University of Science and TechnologyOTHER | 1 | Oct 23, 2017 | clinicaltrials |
| NCT01431599 | Short-course Preoperative Chemoradiotherapy for Rectal Cancer(KROG 11-02) | unknown | Phase 2 | 80 | Jong Hoon LeeOTHER | 1 | Oct 10, 2017 | clinicaltrials |
| NCT03302858 | A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand | unknown | Phase 2 | 70 | Stephen E. GoldstoneOTHER | 1 | Oct 5, 2017 | clinicaltrials |
| NCT02618356 | Combined Use of Raltitrexed and S-1 as Treatment for Patients With Metastasizing Colorectal Cancer | unknown | Phase 2 | 82 | Fudan UniversityOTHER | 1 | Oct 2, 2017 | clinicaltrials |
| NCT03280407 | NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer(NEOLAR) | unknown | Phase 2 | 124 | Zealand University HospitalOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT01952951 | Preoperative Chemoradiation Followed by Chemotherapy for Locally Advanced Rectal Cancer(PREPARE) | unknown | Phase 2 | 110 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 13, 2017 | clinicaltrials |
| NCT01716949 | Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer(HyRec) | unknown | Phase 1 / Phase 2 | 59 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT03220984 | The Safety and Efficacy Test of Immuncell-LC to Treat Refractory Metastatic Colorectal Cancer | unknown | Phase 2 | 28 | Gangnam Severance HospitalOTHER | 1 | Jul 21, 2017 | clinicaltrials |
| NCT03210064 | Clinical Study of Apatinib and 5-Fu Combination Regimen to Treat Advanced Colorectal Cancer Patients | unknown | Phase 2 | 42 | Hui ting Xu,MDOTHER | 1 | Jul 6, 2017 | clinicaltrials |
| NCT01930864 | Metformin Plus Irinotecan for Refractory Colorectal Cancer | unknown | Phase 2 | 41 | Barretos Cancer HospitalOTHER | 1 | Jun 22, 2017 | clinicaltrials |
| NCT03132025 | Study of Apatinib and Capecitabine Combination to Maintain Treating Metastatic Colorectal Cancer | unknown | Phase 2 | 40 | Yanqiao ZhangOTHER | 0 | Apr 27, 2017 | clinicaltrials |
| NCT03076957 | A Phase 1/2a Study to Assess the Safety and Efficacy of CKD-516 Tab. in Combination With Irinotecan Inj. | unknown | Phase 1 / Phase 2 | 24 | Chong Kun Dang PharmaceuticalINDUSTRY | 1 | Mar 10, 2017 | clinicaltrials |
| NCT03053167 | Irinotecan Plus Raltitrexed as Second-line Treatment in Advanced Colorectal Cancer Patients | unknown | Phase 2 | 100 | China Medical University, ChinaOTHER | 1 | Feb 14, 2017 | clinicaltrials |
| NCT02715882 | Clinical Study of Safety and Tolerability of CBLB502 as a Neo-adjuvant Treatment in Patients With Colorectal Cancer | unknown | Phase 2 | 40 | BioLab 612 LLCINDUSTRY | 1 | Feb 9, 2017 | clinicaltrials |
| NCT03047525 | Study of DC-CTL Combined With CIK for Advanced Solid Tumor | unknown | Phase 1 / Phase 2 | 200 | Xiaoyi HuangOTHER | 1 | Feb 9, 2017 | clinicaltrials |
| NCT03013712 | A Clinical Research of CAR T Cells Targeting EpCAM Positive Cancer(CARTEPC) | unknown | Phase 1 / Phase 2 | 60 | First Affiliated Hospital of Chengdu Medical CollegeOTHER | 1 | Jan 6, 2017 | clinicaltrials |
| NCT02617134 | CAR-T Cell Immunotherapy in MUC1 Positive Solid Tumor | unknown | Phase 1 / Phase 2 | 20 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 6, 2016 | clinicaltrials |
| NCT02839954 | CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor | unknown | Phase 1 / Phase 2 | 10 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 6, 2016 | clinicaltrials |
| NCT02978313 | Cetuximab Monotherapy Maintenance Treatment in mCRC | unknown | Phase 2 / Phase 3 | 500 | Ruijin HospitalOTHER | 0 | Nov 30, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Jan 11, 2019source: clinicaltrials