Clinical trial · Interventional
A Novel Technique of HALS With CME and CVL for RCC
A Novel Technique of Hand-assisted Laparoscopic Right Hemicolectomy With Complete Mesocolic Excision and Central Vascular Ligation for Right Colon Cancer: A Randomized Controlled Trial
NCT02625272CI-TRIAL-00030254unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine the short and long outcomes of the novel technique of hand-assisted laparoscopic right hemicolectomy with complete mesocolic excision and central vascular ligation for right colon cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Neoplasms | Colon Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Group A | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Group A
- description
- The novel hand-assisted laparoscopic surgery with complete mesocolic excision and central vascular ligation for right colon cancer. In this group, greater omentum, transverse colon, and ileum were brought out through the hand-port incision at the beginning of the operation and divided extracorporeally.
- interventionNames
- Procedure: Group A
- type
- NO_INTERVENTION
- label
- Group B
- description
- novel laparoscopic surgery with complete mesocolic excision and central vascular ligation for right colon cancer. In this group, greater omentum, transverse colon, and ileum were divided at the beginning of the operation intracorporeally.
- type
- NO_INTERVENTION
- label
- Group C
- description
- the traditional laparoscopic surgery with complete mesocolic excision and central vascular ligation for right colon cancer.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically confirmed right colon cancer * Clinical stage: I, II, III * No preoperative chemoradiotherapy * No past surgical history * No serious preoperative complication * Eastern Cooperative Oncology Group (ECOG) performance status (PS): 0-1 * Age: 18-80 * Written informed consent Exclusion Criteria: * Malignant neoplasm of other sites (including transverse, descending, sigmoid colon cancer, and rectal cancer) * Metastatic cancer * Multiple cancer * Serious complications (including bowel perforation, bowel obstruction, gastrointestinal hemorrhage) * Pregnant and lactating women * Psychological disorder * Steroid administration * Cardiac infarction within six months * Severe pulmonary emphysema and pulmonary fibrosis
References
Publications (22)
- BACKGROUNDPeters WR, Bartels TL. Minimally invasive colectomy: are the potential benefits realized? Dis Colon Rectum. 1993 Aug;36(8):751-6. doi: 10.1007/BF02048366. PMID 8348865
- BACKGROUNDVeldkamp R, Kuhry E, Hop WC, Jeekel J, Kazemier G, Bonjer HJ, Haglind E, Pahlman L, Cuesta MA, Msika S, Morino M, Lacy AM; COlon cancer Laparoscopic or Open Resection Study Group (COLOR). Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol. 2005 Jul;6(7):477-84. doi: 10.1016/S1470-2045(05)70221-7. PMID 15992696
- BACKGROUNDColon Cancer Laparoscopic or Open Resection Study Group; Buunen M, Veldkamp R, Hop WC, Kuhry E, Jeekel J, Haglind E, Pahlman L, Cuesta MA, Msika S, Morino M, Lacy A, Bonjer HJ. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol. 2009 Jan;10(1):44-52. doi: 10.1016/S1470-2045(08)70310-3. Epub 2008 Dec 13. PMID 19071061
- BACKGROUNDNaitoh T, Gagner M, Garcia-Ruiz A, Heniford BT, Ise H, Matsuno S. Hand-assisted laparoscopic digestive surgery provides safety and tactile sensation for malignancy or obesity. Surg Endosc. 1999 Feb;13(2):157-60. doi: 10.1007/s004649900928. PMID 9918620
- BACKGROUNDMeijer DW, Bannenberg JJ, Jakimowicz JJ. Hand-assisted laparoscopic surgery: an overview. Surg Endosc. 2000 Oct;14(10):891-5. doi: 10.1007/s004640020019. PMID 11080398
- BACKGROUNDAalbers AG, Biere SS, van Berge Henegouwen MI, Bemelman WA. Hand-assisted or laparoscopic-assisted approach in colorectal surgery: a systematic review and meta-analysis. Surg Endosc. 2008 Aug;22(8):1769-80. doi: 10.1007/s00464-008-9857-4. Epub 2008 Apr 24. PMID 18437486
- BACKGROUNDChung CC, Ng DC, Tsang WW, Tang WL, Yau KK, Cheung HY, Wong JC, Li MK. Hand-assisted laparoscopic versus open right colectomy: a randomized controlled trial. Ann Surg. 2007 Nov;246(5):728-33. doi: 10.1097/SLA.0b013e318123fbdf.