Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05853094 | Postoperative Effects of Different Enterostomy Approaches | recruiting | N/A | 300 | Fudan UniversityOTHER | 1 | May 19, 2023 | clinicaltrials |
| NCT05861505 | COLLISION RELAPSE Trial | recruiting | Phase 3 | 360 | Amsterdam UMC, location VUmcOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT05316103 |
| recruiting |
| N/A |
| 68 |
| Nanfang Hospital, Southern Medical UniversityOTHER |
| 1 |
| May 12, 2023 |
| clinicaltrials |
| NCT05841134 | Tislelizumab Combined With Chemotherapy (CAPOX) in the Perioperative Treatment of MSI-H/dMMR Stage II or III Colorectal Cancer | not yet recruiting | Phase 2 | 25 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | May 9, 2023 | clinicaltrials |
| NCT05850559 | Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt | not yet recruiting | — | 50 | Assiut UniversityOTHER | 0 | May 9, 2023 | clinicaltrials |
| NCT04087421 | Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome | recruiting | Phase 3 | 114 | University of AarhusOTHER | 1 | May 3, 2023 | clinicaltrials |
| NCT05827471 | Clinical Study of QSOX1 as a Biomarker for Colon Cancer | not yet recruiting | — | 400 | Qianfoshan HospitalOTHER | 0 | Apr 25, 2023 | clinicaltrials |
| NCT05815082 | ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer | recruiting | Phase 3 | 490 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05807984 | Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion | not yet recruiting | Phase 2 | 31 | Xin CaiOTHER | 1 | Apr 11, 2023 | clinicaltrials |
| NCT05794750 | Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13）(AK104-IIT-13) | not yet recruiting | Phase 2 | 50 | JIN JINGOTHER | 0 | Apr 6, 2023 | clinicaltrials |
| NCT05797077 | Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA | recruiting | Phase 3 | 346 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 4, 2023 | clinicaltrials |
| NCT01763125 | Establishment of a Tumor Bank for Blood Samples | recruiting | — | 10,000 | Medical University of ViennaOTHER | 4 | Mar 23, 2023 | clinicaltrials |
| NCT01789229 | Establishment of a Tumor Bank for Tissue Samples | recruiting | — | 10,000 | Medical University of ViennaOTHER | 3 | Mar 23, 2023 | clinicaltrials |
| NCT05779553 | Evaluation of Serum Tumor Endothelial Marker1 as a Potential Biomarker for Colorectal Cancer Diagnosis and Cancer Progression | not yet recruiting | — | 90 | Assiut UniversityOTHER | 0 | Mar 22, 2023 | clinicaltrials |
| NCT05772923 | Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision(OPAXX) | recruiting | N/A | 168 | The Netherlands Cancer InstituteOTHER | 1 | Mar 17, 2023 | clinicaltrials |
| NCT05768503 | Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC | recruiting | Phase 3 | 176 | Sun Yat-sen UniversityOTHER | 1 | Mar 14, 2023 | clinicaltrials |
| NCT05733000 | CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors | recruiting | Phase 2 | 94 | Northwestern UniversityOTHER | 1 | Mar 10, 2023 | clinicaltrials |
| NCT04245683 | Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population | recruiting | — | 50 | Bassett HealthcareOTHER | 1 | Mar 7, 2023 | clinicaltrials |
| NCT04842006 | Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer(SYNCOPE) | recruiting | N/A | 93 | Helsinki University Central HospitalOTHER | 1 | Mar 6, 2023 | clinicaltrials |
| NCT05136326 | Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer(CATARTIC) | recruiting | Phase 2 | 21 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Mar 1, 2023 | clinicaltrials |
| NCT05747716 | SBRT Combined With Fruquintinib Plus PD-1/CTLA-4 Antibody for Third-line Treatment in mCRC | not yet recruiting | Phase 2 | 44 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Feb 28, 2023 | clinicaltrials |
| NCT04743102 | Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer(BIOPSY) | recruiting | N/A | 260 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT05202314 | Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer(NACSOC-02) | recruiting | N/A | 20 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT05725200 | Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer(EVIDENT) | recruiting | Phase 2 | 40 | Oslo University HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT03466424 | Short-course Radiotherapy (5×6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer | recruiting | — | 9 | Fujian Medical University Union HospitalOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT05501353 | Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics Methods | recruiting | — | 125 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Feb 8, 2023 | clinicaltrials |
| NCT04014530 | Pembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study(ATAPEMBRO) | recruiting | Phase 1 / Phase 2 | 47 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT04304209 | Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer | active not recruiting | Phase 2 | 195 | Sun Yat-sen UniversityOTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT05704413 | Digestive Biobank for Exploring Microbiota-host Interactions(BiomHost) | recruiting | — | 500 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jan 30, 2023 | clinicaltrials |
| NCT02669992 | Loop Ileostomy Closure:Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site?(LISTO) | recruiting | N/A | 400 | Karolinska University HospitalOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05699746 | CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD | not yet recruiting | Phase 3 | 38 | Zhejiang UniversityOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05696002 | Advanced Pelvic Surgical Oncology Database - Prospective Observational Study | recruiting | — | 300 | Glasgow Royal InfirmaryOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT04486131 | Lateral Nodal Recurrence in Rectal Cancer(LaNoReC) | recruiting | — | 200 | Amsterdam UMC, location VUmcOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT05689775 | Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap | recruiting | — | 40 | Oslo University HospitalOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT04833387 | PD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal Cancer | active not recruiting | Phase 2 | 30 | Sun Yat-sen UniversityOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT05676190 | Clinical Study on the Efficacy of Autologous Cell Factor Induced Killer Cells in the Treatment of Colorectal Cancer | recruiting | N/A | 80 | ShiCang YuOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT05671809 | Effects of Different Treatment for Anorectal Function of Patients With Rectal Cancer(ARF-RC) | not yet recruiting | — | 402 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jan 5, 2023 | clinicaltrials |
| NCT05236972 | PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer | recruiting | Phase 3 | 323 | Sun Yat-sen UniversityOTHER | 1 | Dec 30, 2022 | clinicaltrials |
| NCT03587480 | Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy(TELEPHOME) | recruiting | N/A | 250 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Nov 25, 2022 | clinicaltrials |
| NCT04281667 | Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery(MOBILE2) | active not recruiting | Phase 4 | 604 | Helsinki University Central HospitalOTHER | 1 | Nov 17, 2022 | clinicaltrials |
| NCT04512937 | Computer Navigation-assisted Surgery for Locally Advanced and Recurrent Rectal Cancer(NAVI-LARRC) | active not recruiting | N/A | 20 | Oslo University HospitalOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT04871399 | Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer(CoME-In) | recruiting | N/A | 416 | University of Turin, ItalyOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT05359393 | A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis(Miracle-1) | not yet recruiting | Phase 2 | 52 | Fudan UniversityOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT05495776 | Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer(MSIRus22) | recruiting | — | 2,500 | State Scientific Centre of Coloproctology, Russian FederationOTHER_GOV | 1 | Oct 25, 2022 | clinicaltrials |
| NCT05579353 | The Roles of Exosomal Circ-LRBA and 451/CRTC2 Signaling Axis in Colorectal Cancer | recruiting | — | 200 | Jingbo ChenOTHER | 1 | Oct 13, 2022 | clinicaltrials |
| NCT04527861 | Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer(CSILS) | recruiting | N/A | 710 | Ruijin HospitalOTHER | 1 | Oct 10, 2022 | clinicaltrials |
| NCT05427669 | Adjuvant mFOLFOXIRI vs. mFOLFOX6 in MRD Positive Stage II-III Colorectal Cancer (AFFORD)(AFFORD) | not yet recruiting | Phase 3 | 340 | Yanhong DengOTHER | 0 | Oct 7, 2022 | clinicaltrials |
| NCT05566249 | A Study to Validate the Safety and Feasibility of ArtiSential in Colorectal Cancer Surgery Using Prospectively Constructed Multi-center Registry | recruiting | — | 1,000 | Samsung Medical CenterOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT05563922 | Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma(OP-TNT) | recruiting | Phase 2 | 56 | Shanghai Zhongshan HospitalOTHER | 1 | Oct 3, 2022 | clinicaltrials |
| NCT04673955 | BRAF Inhibitor Encorafenib And Cetuximab Real Life Investigation of Next Generation CRC Treatment(BERING-CRC) | recruiting | — | 500 | Pierre Fabre Pharma GmbHINDUSTRY | 2 | Sep 29, 2022 | clinicaltrials |
Data updated 23 days agoSource updated May 19, 2023source: clinicaltrials