Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05985109 | KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer | recruiting | Phase 2 | 98 | Peking University Cancer Hospital & InstituteOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT06082648 | Study of Brain-Gut Function Reconstruction After Intersphincteric Resection for Ultra-Low Rectal Tumors | recruiting | N/A | 57 | Huashan HospitalOTHER | 1 | Oct 13, 2023 | clinicaltrials |
| NCT06041945 |
| Artificial Intelligence to Implement Cost-saving Strategies for Colonoscopy Screening Based on in Vivo Prediction of Polyp Histology(SAVE) |
| recruiting |
| N/A |
| 1,800 |
| Istituto Clinico HumanitasOTHER |
| 1 |
| Oct 4, 2023 |
| clinicaltrials |
| NCT05450029 | Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer(SILAR) | recruiting | Phase 2 | 51 | Yanhong DengOTHER | 1 | Sep 26, 2023 | clinicaltrials |
| NCT05438836 | Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer(ROAR-A) | recruiting | — | 205 | Herlev HospitalOTHER | 1 | Sep 25, 2023 | clinicaltrials |
| NCT04616495 | Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases(TRASMETIR) | recruiting | — | 30 | Hospital Universitario La FeOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT06043466 | A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors | recruiting | Phase 1 | 30 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Sep 21, 2023 | clinicaltrials |
| NCT06043999 | Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients | recruiting | N/A | 392 | Sun Yat-sen UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT05962502 | Cetuximab Plus Irinotecan in Patients With NeoRAS Wild-type Metastatic Colorectal Cancer In Third-line Therapy | recruiting | Phase 2 | 54 | Sun Yat-sen UniversityOTHER | 1 | Aug 31, 2023 | clinicaltrials |
| NCT05336539 | A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou | recruiting | — | 80,000 | Singlera Genomics Inc.INDUSTRY | 1 | Aug 29, 2023 | clinicaltrials |
| NCT05871762 | Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer(COMREC) | recruiting | — | 3,705 | Peking Union Medical College HospitalOTHER | 1 | Aug 28, 2023 | clinicaltrials |
| NCT05879783 | Optical Biopsy for Peritoneal Nodules in Colorectal Patients | recruiting | N/A | 278 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT05984485 | The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer(TaLaR-02) | recruiting | Phase 3 | 766 | Sun Yat-sen UniversityOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT05984576 | Radiotherapy & Total Neoadjuvant Therapy for Recurrent Rectal Cancer in Previously Irradiated Patients, an Italian Association for Radiotherapy and Clinical Oncology (AIRO)-GI Platform: a Multi-centre Prospective Observational Study(RETRY) | recruiting | — | 88 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT05914389 | Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer(ICONIC) | recruiting | Phase 2 | 100 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Aug 8, 2023 | clinicaltrials |
| NCT05734300 | The "SPARCOL" Study | recruiting | N/A | 48 | Zealand University HospitalOTHER | 1 | Jul 25, 2023 | clinicaltrials |
| NCT05939661 | A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer(AMBITION) | recruiting | Phase 2 | 45 | Osaka UniversityOTHER | 1 | Jul 11, 2023 | clinicaltrials |
| NCT05797467 | Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients | recruiting | Phase 3 | 366 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | May 24, 2023 | clinicaltrials |
| NCT04959604 | Lymph Node Mapping Via Flourescent Dye in Colon Cancer | recruiting | N/A | 30 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | May 23, 2023 | clinicaltrials |
| NCT05853094 | Postoperative Effects of Different Enterostomy Approaches | recruiting | N/A | 300 | Fudan UniversityOTHER | 1 | May 19, 2023 | clinicaltrials |
| NCT05861505 | COLLISION RELAPSE Trial | recruiting | Phase 3 | 360 | Amsterdam UMC, location VUmcOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT05316103 | Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy | recruiting | N/A | 68 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | May 12, 2023 | clinicaltrials |
| NCT04087421 | Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome | recruiting | Phase 3 | 114 | University of AarhusOTHER | 1 | May 3, 2023 | clinicaltrials |
| NCT05815082 | ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer | recruiting | Phase 3 | 490 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05797077 | Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA | recruiting | Phase 3 | 346 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 4, 2023 | clinicaltrials |
| NCT01763125 | Establishment of a Tumor Bank for Blood Samples | recruiting | — | 10,000 | Medical University of ViennaOTHER | 4 | Mar 23, 2023 | clinicaltrials |
| NCT01789229 | Establishment of a Tumor Bank for Tissue Samples | recruiting | — | 10,000 | Medical University of ViennaOTHER | 3 | Mar 23, 2023 | clinicaltrials |
| NCT05772923 | Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision(OPAXX) | recruiting | N/A | 168 | The Netherlands Cancer InstituteOTHER | 1 | Mar 17, 2023 | clinicaltrials |
| NCT05768503 | Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC | recruiting | Phase 3 | 176 | Sun Yat-sen UniversityOTHER | 1 | Mar 14, 2023 | clinicaltrials |
| NCT05733000 | CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors | recruiting | Phase 2 | 94 | Northwestern UniversityOTHER | 1 | Mar 10, 2023 | clinicaltrials |
| NCT04245683 | Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population | recruiting | — | 50 | Bassett HealthcareOTHER | 1 | Mar 7, 2023 | clinicaltrials |
| NCT04842006 | Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer(SYNCOPE) | recruiting | N/A | 93 | Helsinki University Central HospitalOTHER | 1 | Mar 6, 2023 | clinicaltrials |
| NCT05136326 | Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer(CATARTIC) | recruiting | Phase 2 | 21 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Mar 1, 2023 | clinicaltrials |
| NCT04743102 | Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer(BIOPSY) | recruiting | N/A | 260 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT05202314 | Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer(NACSOC-02) | recruiting | N/A | 20 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT05725200 | Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer(EVIDENT) | recruiting | Phase 2 | 40 | Oslo University HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT03466424 | Short-course Radiotherapy (5×6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer | recruiting | — | 9 | Fujian Medical University Union HospitalOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT05501353 | Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics Methods | recruiting | — | 125 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Feb 8, 2023 | clinicaltrials |
| NCT04014530 | Pembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study(ATAPEMBRO) | recruiting | Phase 1 / Phase 2 | 47 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT05704413 | Digestive Biobank for Exploring Microbiota-host Interactions(BiomHost) | recruiting | — | 500 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jan 30, 2023 | clinicaltrials |
| NCT02669992 | Loop Ileostomy Closure:Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site?(LISTO) | recruiting | N/A | 400 | Karolinska University HospitalOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05696002 | Advanced Pelvic Surgical Oncology Database - Prospective Observational Study | recruiting | — | 300 | Glasgow Royal InfirmaryOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT04486131 | Lateral Nodal Recurrence in Rectal Cancer(LaNoReC) | recruiting | — | 200 | Amsterdam UMC, location VUmcOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT05689775 | Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap | recruiting | — | 40 | Oslo University HospitalOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT05676190 | Clinical Study on the Efficacy of Autologous Cell Factor Induced Killer Cells in the Treatment of Colorectal Cancer | recruiting | N/A | 80 | ShiCang YuOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT05236972 | PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer | recruiting | Phase 3 | 323 | Sun Yat-sen UniversityOTHER | 1 | Dec 30, 2022 | clinicaltrials |
| NCT03587480 | Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy(TELEPHOME) | recruiting | N/A | 250 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Nov 25, 2022 | clinicaltrials |
| NCT04871399 | Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer(CoME-In) | recruiting | N/A | 416 | University of Turin, ItalyOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT05495776 | Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer(MSIRus22) | recruiting | — | 2,500 | State Scientific Centre of Coloproctology, Russian FederationOTHER_GOV | 1 | Oct 25, 2022 | clinicaltrials |
| NCT05579353 | The Roles of Exosomal Circ-LRBA and 451/CRTC2 Signaling Axis in Colorectal Cancer | recruiting | — | 200 | Jingbo ChenOTHER | 1 | Oct 13, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Oct 26, 2023source: clinicaltrials