Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06310564 | Low and Intermediate Risk OliGometastatic ColoREctal CancEr PatieNts Treated with Stereotactic ABlative Radiotherapy(GREENLaIT-SABR) | recruiting | N/A | 204 | IRCCS Sacro Cuore Don Calabria di NegrarOTHER | 1 | Dec 2, 2024 | clinicaltrials |
| NCT06711211 | Spanish Registry of Digestive Tumours RETUD(RETUD) | recruiting | — | 20,000 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) |
| 1 |
| Dec 2, 2024 |
| clinicaltrials |
| NCT06405139 | Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine As Conversion Therapy of Locally Advanced Colorectal Cancer | recruiting | Phase 2 | 36 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Nov 29, 2024 | clinicaltrials |
| NCT06709885 | HDAC Inhibitor Combination With Chemoimmunotherapy in the Neoadjuvant Treatment of pMMR Locally Advanced Colon Cancer | recruiting | Phase 2 | 100 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Nov 29, 2024 | clinicaltrials |
| NCT05000697 | Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait(CCHOWW) | recruiting | N/A | 216 | Hospital Alemão Oswaldo CruzOTHER | 3 | Nov 27, 2024 | clinicaltrials |
| NCT06637215 | Clinical Research on the Treatment Model of Ambulatory Surgery for Colorectal Cancer | recruiting | N/A | 352 | First Hospital of China Medical UniversityOTHER | 1 | Nov 27, 2024 | clinicaltrials |
| NCT05824975 | A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) | recruiting | Phase 1 / Phase 2 | 358 | GI Innovation, Inc.INDUSTRY | 2 | Nov 25, 2024 | clinicaltrials |
| NCT02754115 | An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | recruiting | — | 400 | Tata Memorial CentreOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT04999007 | Artificial Intelligence Assists Surgeons' Decision Making | recruiting | N/A | 616 | Jichao QinOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT06631443 | Asian Watch-and-Wait Database (AWWD)(AWWD) | recruiting | — | 337 | Tata Memorial CentreOTHER | 1 | Nov 20, 2024 | clinicaltrials |
| NCT05933876 | The Impact of Radiotherapy on Oligometastatic Cancer | recruiting | — | 2,000 | Institut Investigacio Sanitaria Pere VirgiliOTHER | 1 | Nov 18, 2024 | clinicaltrials |
| NCT06612281 | Evaluation of Gixam's Performance in a FIT Negative Population | recruiting | Phase 2 | 400 | Jubaan Ltd.INDUSTRY | 1 | Nov 14, 2024 | clinicaltrials |
| NCT06688383 | Anastomotic Leakage After Right Hemicolectomy for Cancer, a Prospective Multicenter Study of SICO-CC Network(ALRIGHT) | recruiting | — | 1,839 | San Luigi Gonzaga HospitalOTHER | 1 | Nov 14, 2024 | clinicaltrials |
| NCT06033976 | Endoscopic Submucosal Dissection Registry(ESDREG) | recruiting | — | 200 | Carol Davila University of Medicine and PharmacyOTHER | 1 | Nov 12, 2024 | clinicaltrials |
| NCT06411600 | Combination Therapy for BRAF-V600E Metastatic CRCm(BRAVE) | recruiting | Phase 2 | 94 | Vall d'Hebron Institute of OncologyOTHER | 1 | Nov 8, 2024 | clinicaltrials |
| NCT03874026 | Study of Folfiri/Cetuximab in FcGammaRIIIa V/V Stage IV Colorectal Cancer Patients(CIFRA) | recruiting | Phase 2 | 34 | National Cancer Institute, NaplesOTHER | 1 | Nov 7, 2024 | clinicaltrials |
| NCT06520683 | Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer(SMALLER) | recruiting | Phase 3 | 180 | Sun Yat-sen UniversityOTHER | 1 | Nov 7, 2024 | clinicaltrials |
| NCT06530303 | Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer(BAH248) | recruiting | Phase 1 / Phase 2 | 85 | Essen BiotechOTHER | 1 | Nov 5, 2024 | clinicaltrials |
| NCT04103372 | Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery(PRESERVE) | recruiting | N/A | 200 | Imperial College LondonOTHER | 1 | Nov 4, 2024 | clinicaltrials |
| NCT05424692 | Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer | recruiting | N/A | 200 | Peking Union Medical College HospitalOTHER | 1 | Nov 4, 2024 | clinicaltrials |
| NCT06663839 | A Study of NILK-2301 in Patients with Locally Advanced or Metastatic Low Tumor Volume (LTV) Colorectal Cancer | recruiting | Phase 1 | 25 | Light Chain Bioscience - Novimmune SAINDUSTRY | 1 | Oct 29, 2024 | clinicaltrials |
| NCT04516681 | Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer | recruiting | Phase 3 | 400 | Fudan UniversityOTHER | 1 | Oct 24, 2024 | clinicaltrials |
| NCT06653452 | Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Cancer | recruiting | N/A | 30 | Peking Union Medical College HospitalOTHER | 1 | Oct 22, 2024 | clinicaltrials |
| NCT06653478 | Development and Demonstration of Intelligent Assessment Based on Multi-modal Information Fusion for Tumor Risk and Diagnosis and Treatment | recruiting | — | 3,000 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Oct 22, 2024 | clinicaltrials |
| NCT06207656 | Study to Evaluate the Efficacy and Safety of Cetuximab in Combination with Encorafenib Plus Binimetinib As Induction Treatment in BRAF V600E Mutated MSS Initially Resectable or Potentially Resectable Advanced Colorectal Cancer(CEBBRA) | recruiting | Phase 2 | 70 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Oct 21, 2024 | clinicaltrials |
| NCT02222844 | Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers(IMPRESS) | recruiting | N/A | 244 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT02246634 | Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)(SERENADE) | recruiting | N/A | 282 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT02579278 | Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion(ctDNA) | recruiting | — | 100 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT02704520 | Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial(TRIGGER) | recruiting | N/A | 441 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT03303547 | Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits(COMET) | recruiting | N/A | 200 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT04547166 | A Clinical Study to Evaluate Efficacy and Safety of Serplulimab（HLX10） Combined With Bevacizumab（HLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC) | recruiting | Phase 2 / Phase 3 | 568 | Shanghai Henlius BiotechINDUSTRY | 2 | Oct 17, 2024 | clinicaltrials |
| NCT06275958 | DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer(DOSAGE) | recruiting | Phase 3 | 587 | Leiden University Medical CenterOTHER | 1 | Oct 16, 2024 | clinicaltrials |
| NCT06633133 | Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision | recruiting | N/A | 620 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Oct 16, 2024 | clinicaltrials |
| NCT05250648 | Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)(GECOP-MMC) | recruiting | Phase 4 | 216 | Hospital Universitario de FuenlabradaOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT05955196 | Test of CD47-SIRPα Inhibitors on the Immune Microenvironment Colon Cancer(MACROSWITCH) | recruiting | — | 115 | Institut Paoli-CalmettesOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06184698 | Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer | recruiting | Phase 2 | 173 | Hebei Medical University Fourth HospitalOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06632886 | AI-Assisted Non-Contrast CT for Multi-Cancer Screening | recruiting | N/A | 1,000,000 | Guo ShiWeiOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06220045 | Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.(PROFIMESH) | recruiting | N/A | 60 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Oct 8, 2024 | clinicaltrials |
| NCT06220058 | Comparing Polypropylene Mesh and "Small Bites" Technique in Emergency Colorectal Surgery's Midline Laparotomy Closure. Study for Incisional Hernia Prevention.(BITEME) | recruiting | N/A | 148 | Fernandez ZamoraOTHER | 1 | Oct 8, 2024 | clinicaltrials |
| NCT06629051 | 6-year Follow-up Data After the Berberine Intervention Trial | recruiting | — | 891 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Oct 8, 2024 | clinicaltrials |
| NCT06630962 | Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care(COST-FIN) | recruiting | N/A | 200 | Northwestern UniversityOTHER | 1 | Oct 8, 2024 | clinicaltrials |
| NCT06452745 | Early Diagnosis of Colorectal Cancer Based on a Non-invasive Metabolomics Profile(EarlyCRC) | recruiting | — | 2,000 | Institut Investigacio Sanitaria Pere VirgiliOTHER | 1 | Oct 2, 2024 | clinicaltrials |
| NCT05628038 | The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer(TORCH-R) | recruiting | Phase 2 | 93 | Fudan UniversityOTHER | 1 | Oct 1, 2024 | clinicaltrials |
| NCT06613581 | Patient-led Follow-up from Home After Surgery for Colorectal Carcinoma(PROMISE) | recruiting | N/A | 200 | Erasmus Medical CenterOTHER | 1 | Sep 26, 2024 | clinicaltrials |
| NCT06259552 | A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors(SPX-303) | recruiting | Phase 1 | 232 | SparX Biotech(Jiangsu) Co., Ltd.OTHER | 1 | Sep 24, 2024 | clinicaltrials |
| NCT06609551 | ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study(ZJCH-CRCC-1) | recruiting | Phase 3 | 312 | Zhejiang Cancer HospitalOTHER | 1 | Sep 24, 2024 | clinicaltrials |
| NCT05961969 | Robotic Top-down Intersphincteric Resection | recruiting | — | 40 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT05964530 | Radical vs Local Excision for Rectal Cancer With Clinically Complete Remission | recruiting | N/A | 180 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT05970133 | Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer | recruiting | N/A | 300 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT06024837 | Performance of Spectral CT-scan in Patients With Metastatic Colorectal Cancer: a Prospective Multicentre Study | recruiting | — | 100 | Centre Hospitalier Universitaire de Saint EtienneOTHER | 1 | Sep 20, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Dec 2, 2024source: clinicaltrials