Clinical trial · Interventional
Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with suspected or proven sigmoid colon adenocarcinoma, eligible for curative treatment whose MRI can be reviewed prior to surgery and has no decision regarding radical treatment are eligible. Patient are randomised to the control arm which the standard care of preoperative CT imaging and subsequent discussion by the Multidisciplinary Team or the interventional arm which has the additional use of MRI imaging and subsequent discussion by the Multidisciplinary Team. Patients are followed up at 1 and 3 years together with QoL questionnaires.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Colon, Sigmoid | — | UNRESOLVED | — |
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| General Surgery | — | UNRESOLVED | — |
| Magnetic Resonance Imaging | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Preoperative MRI scan | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- Preoperative CT scan
- description
- CT-imaging of chest and abdomen / pelvis before surgery (standard treatment)
- type
- EXPERIMENTAL
- label
- Preoperative MRI scan
- description
- Standard treatment plus an additional MRI scan before surgery
- interventionNames
- Other: Preoperative MRI scan
- type
- NO_INTERVENTION
- label
- Observational
- description
- Observational only
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria: 1. Have a suspected or proven sigmoid colon adenocarcinoma 2. Is eligible for curative treatment 3. Has no irresectable metastatic disease 4. MRI can be reviewed by an MDT prior to surgery 5. Has no decision regarding radical treatment 6. Have provided written informed consent to participate in the study 7. Be aged 16 years or over Exclusion Criteria: 1. Have metastatic disease (including resectable liver metastases) 2. Have a synchronous second malignancy 3. Are contraindicated for MRI 4. Are contraindicated for or have allergy to Buscopan (e.g. glaucoma, small or large bowel obstruction, GFR\<30) 5. Have severe co-morbidities or previous medical history that prevent the application of eventual chemo/radiotherapy
References
Publications (0)
Data not yet available