Subtype
Intracranial Neoplasm
CI-CAN-00001030Explore in graph →
Non-malignant521 active trials34 evidence items
- NCIt
- C4953
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Subtype
CI-CAN-00001030Explore in graph →
Clinical trials
2,177 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06055790 | Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis | recruiting | Early Phase 1 | 20 | University of ArizonaOTHER | 1 | Sep 21, 2026 | clinicaltrials |
| NCT07039760 | Asciminib With or Without Sildenafil for Brain Tumors | not yet recruiting | Early Phase 1 | 12 | Washington University School of MedicineOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma(GBM) |
| recruiting |
| Early Phase 1 |
| 15 |
| Abramson Cancer Center at Penn MedicineOTHER |
| 1 |
| Sep 9, 2026 |
| clinicaltrials |
| NCT06959979 | Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma | recruiting | Early Phase 1 | 60 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT03122197 | Study of Letrozole in Recurrent Gliomas | recruiting | Early Phase 1 | 39 | University of CincinnatiOTHER | 1 | Aug 18, 2026 | clinicaltrials |
| NCT03542409 | Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas | completed | Early Phase 1 | 53 | University of UtahOTHER | 1 | Aug 10, 2026 | clinicaltrials |
| NCT05047913 | Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR | active not recruiting | Early Phase 1 | 20 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT06942039 | Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation | recruiting | Early Phase 1 | 15 | C17 CouncilOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT07210632 | Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) | recruiting | Early Phase 1 | 38 | Eben RosenthalOTHER | 1 | Jul 1, 2026 | clinicaltrials |
| NCT07493447 | Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures | recruiting | Early Phase 1 | 30 | Eben RosenthalOTHER | 1 | Jun 30, 2026 | clinicaltrials |
| NCT06333899 | Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion | recruiting | Early Phase 1 | 15 | Nationwide Children's HospitalOTHER | 6 | Jun 29, 2026 | clinicaltrials |
| NCT07050836 | Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation | terminated | Early Phase 1 | 2 | University of Colorado, DenverOTHER | 1 | Jun 22, 2026 | clinicaltrials |
| NCT07460232 | FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease | recruiting | Early Phase 1 | 50 | Mayo ClinicOTHER | 1 | Jun 22, 2026 | clinicaltrials |
| NCT05029960 | Tolerability and Activity of Brivaracetam (BRV) in Patients With Diffuse Gliomas | terminated | Early Phase 1 | 3 | University of RochesterOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT04895592 | Radiosurgery Before Surgery for the Treatment of Brain Metastases | completed | Early Phase 1 | 26 | Emory UniversityOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT07568366 | AI in Endoscopic Transsphenoidal Surgery | not yet recruiting | Early Phase 1 | 30 | University College, LondonOTHER | 1 | May 5, 2026 | clinicaltrials |
| NCT06810336 | Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery | recruiting | Early Phase 1 | 40 | University of VirginiaOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT07017816 | A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.(JACOB) | recruiting | Early Phase 1 | 18 | Children's National Research InstituteOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT03163368 | Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors | active not recruiting | Early Phase 1 | 25 | Cedars-Sinai Medical CenterOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT05704933 | Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases | completed | Early Phase 1 | 1 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT04655404 | A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion | recruiting | Early Phase 1 | 15 | Nationwide Children's HospitalOTHER | 5 | Mar 18, 2026 | clinicaltrials |
| NCT05076513 | Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma | active not recruiting | Early Phase 1 | 42 | Nader SanaiOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT03970226 | Tocilizumab in Children With ACP | active not recruiting | Early Phase 1 | 9 | University of Colorado, DenverOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT04173104 | PET and MRI Imaging of Brain Tumors Using [18F]PARPi | completed | Early Phase 1 | 5 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT04825275 | Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial | terminated | Early Phase 1 | 7 | Milton S. Hershey Medical CenterOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT04869449 | Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas | terminated | Early Phase 1 | 1 | Milton S. Hershey Medical CenterOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT07254104 | Clinical Evaluation of [68Ga]Ga-NOTA-RF PET Imaging Targeting RFVT3 in Patients With Pituitary Tumors | enrolling by invitation | Early Phase 1 | 30 | Peking Union Medical College HospitalOTHER | 1 | Nov 28, 2025 | clinicaltrials |
| NCT04712721 | Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. | terminated | Early Phase 1 | 14 | Novartis PharmaceuticalsINDUSTRY | 2 | Oct 10, 2025 | clinicaltrials |
| NCT05634707 | Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) | active not recruiting | Early Phase 1 | 10 | Duke UniversityOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT06328686 | Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases | recruiting | Early Phase 1 | 10 | Emory UniversityOTHER | 1 | Sep 17, 2025 | clinicaltrials |
| NCT06552260 | A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma | recruiting | Early Phase 1 | 27 | Ugonma ChukwuekeOTHER | 1 | Sep 11, 2025 | clinicaltrials |
| NCT01165632 | Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma | completed | Early Phase 1 | 24 | Mayo ClinicOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT04074785 | Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6(SCCC-06319) | terminated | Early Phase 1 | 10 | University of Texas Southwestern Medical CenterOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT04135807 | Implantable Microdevice In Primary Brain Tumors | recruiting | Early Phase 1 | 12 | Oliver JonasOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT03893487 | Fimepinostat in Treating Brain Tumors in Children and Young Adults(PNOC016) | active not recruiting | Early Phase 1 | 30 | Sabine Mueller, MD, PhDOTHER | 2 | Jul 11, 2025 | clinicaltrials |
| NCT06887673 | Lipid Mediators & Cancer: Montelukast, SPM, and Almonds | not yet recruiting | Early Phase 1 | 56 | University of South FloridaOTHER | 1 | Mar 20, 2025 | clinicaltrials |
| NCT04315064 | Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults with Recurrent Medulloblastoma | completed | Early Phase 1 | 2 | The University of Texas Health Science Center, HoustonOTHER | 1 | Mar 10, 2025 | clinicaltrials |
| NCT02992015 | Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma | completed | Early Phase 1 | 2 | University of Colorado, DenverOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT02020720 | 18F-DOPA-PET in Planning Surgery in Patients With Gliomas | completed | Early Phase 1 | 72 | Mayo ClinicOTHER | 1 | Jan 23, 2025 | clinicaltrials |
| NCT05996432 | Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy | recruiting | Early Phase 1 | 48 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Sep 23, 2024 | clinicaltrials |
| NCT04067960 | Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer | completed | Early Phase 1 | 197 | Mayo ClinicOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT05549024 | 68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients | recruiting | Early Phase 1 | 90 | Peking Union Medical College HospitalOTHER | 1 | Jul 5, 2024 | clinicaltrials |
| NCT04752267 | 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases | completed | Early Phase 1 | 10 | University of Southern CaliforniaOTHER | 1 | May 24, 2024 | clinicaltrials |
| NCT06396481 | Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma(CSAγδTBMG) | not yet recruiting | Early Phase 1 | 25 | Beijing Tiantan HospitalOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT02338037 | Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors | completed | Early Phase 1 | 8 | City of Hope Medical CenterOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT03763396 | Azoles Targeting Recurrent High Grade Gliomas | not yet recruiting | Early Phase 1 | 30 | University Health Network, TorontoOTHER | 1 | Mar 8, 2024 | clinicaltrials |
| NCT06217848 | The Effect of GLP-1 Agonist in Patients With Hypothalamic Obesity: Prospective, Pilot Study | unknown | Early Phase 1 | 50 | Seoul National University HospitalOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT03451123 | FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors | terminated | Early Phase 1 | 1 | University of Alabama at BirminghamOTHER | 1 | Dec 19, 2023 | clinicaltrials |
| NCT02774291 | Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes | terminated | Early Phase 1 | 3 | Albert Einstein College of MedicineOTHER | 1 | Aug 4, 2023 | clinicaltrials |
| NCT05961111 | A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors | unknown | Early Phase 1 | 20 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | Jul 27, 2023 | clinicaltrials |
Data updated 5 days agoSource updated Sep 21, 2026source: clinicaltrials