Subtype
Intracranial Neoplasm
CI-CAN-00001030Explore in graph →
Non-malignant521 active trials34 evidence items
- NCIt
- C4953
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Subtype
CI-CAN-00001030Explore in graph →
Clinical trials
2,177 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05267587 | Preop fSRS for Resectable Brain Metastases | active not recruiting | Phase 2 | 49 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT03605550 | A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma | active not recruiting | Phase 1 | 64 | Nationwide Children's HospitalOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT02852655 | A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma | active not recruiting | Phase 1 | 60 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT05733572 | Safety and Efficacy of the PAINLESS Nerve Growth Factor CHF6467 in Optic Pathway Glioma (OPG)(NGF-OPG) | active not recruiting | Phase 2 | 36 | Benedetto FalsiniOTHER | 1 | Mar 19, 2026 | clinicaltrials |
| NCT02375841 | Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and Caregivers | active not recruiting | — | 309 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT03478462 | Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas(CLOVER-2) | active not recruiting | Phase 1 | 30 | Cellectar Biosciences, Inc.INDUSTRY | 3 | Mar 18, 2026 | clinicaltrials |
| NCT04189172 | MiDura-Study (Neuro-Patch in Duraplasty)(MiDura) | active not recruiting | — | 328 | Aesculap AGINDUSTRY | 2 | Mar 18, 2026 | clinicaltrials |
| NCT03665064 | Long Term Outcome Study in Patients With Pituitary Disorders | active not recruiting | — | 1,500 | University of AlbertaOTHER | 0 | Mar 16, 2026 | clinicaltrials |
| NCT05076513 | Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma | active not recruiting | Early Phase 1 | 42 | Nader SanaiOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT04244019 | FLT-PET / MRI Brain Mets | active not recruiting | — | 30 | University Health Network, TorontoOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT04661384 | Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma | active not recruiting | Phase 1 | 10 | City of Hope Medical CenterOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT03152318 | A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2(rQNestin) | active not recruiting | Phase 1 | 62 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT07446036 | Prediction Model for Postoperative Headache After Transsphenoidal Pituitary Surgery | active not recruiting | — | 500 | Beijing Tiantan HospitalOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT05397106 | Post Market Clinical Follow-up of CODMAN CERTAS Programmable Valve | active not recruiting | — | 160 | Integra LifeSciences CorporationINDUSTRY | 4 | Feb 27, 2026 | clinicaltrials |
| NCT05288439 | A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor | active not recruiting | N/A | 30 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT03970226 | Tocilizumab in Children With ACP | active not recruiting | Early Phase 1 | 9 | University of Colorado, DenverOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT06342908 | A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma | active not recruiting | Phase 1 | 6 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT04478279 | A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 125 | Sapience TherapeuticsINDUSTRY | 2 | Feb 9, 2026 | clinicaltrials |
| NCT04459273 | Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers(FAPI PET RDRC) | active not recruiting | Phase 1 | 26 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07389642 | Brain Oligometastasis in NSCLC(OligoLung) | active not recruiting | — | 46 | University Hospital, BordeauxOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT04049669 | Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG | active not recruiting | Phase 2 | 130 | Theodore S. JohnsonOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT06936813 | The PROMISE Survey | active not recruiting | — | 530 | University Hospital, Basel, SwitzerlandOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT01266096 | PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study | active not recruiting | N/A | 10 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT04165941 | Novel Gamma-Delta (γδ)T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma(DRI) | active not recruiting | Phase 1 | 22 | University of Alabama at BirminghamOTHER | 1 | Dec 26, 2025 | clinicaltrials |
| NCT05503251 | Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases | active not recruiting | Phase 2 | 110 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT03500991 | HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors | active not recruiting | Phase 1 | 10 | Seattle Children's HospitalOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT02374242 | Anti-PD 1 Brain Collaboration for Patients With Melanoma Brain Metastases(ABC) | active not recruiting | Phase 2 | 76 | Melanoma Institute AustraliaOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT02066220 | International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma | active not recruiting | Phase 2 / Phase 3 | 360 | Universitätsklinikum Hamburg-EppendorfOTHER | 16 | Dec 4, 2025 | clinicaltrials |
| NCT04163315 | Multimodal Connectome Study of Brain Tumor-operated Patients(ConnecTC) | active not recruiting | N/A | 30 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT01117168 | Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group | active not recruiting | — | 57,816 | Children's Oncology GroupNETWORK | 1 | Nov 24, 2025 | clinicaltrials |
| NCT05768880 | Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors | active not recruiting | Phase 1 | 72 | Seattle Children's HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06132945 | A Study of Cabozantinib and Nivolumab With Radiation Therapy for People With Renal Cell Carcinoma That Has Spread to the Brain | active not recruiting | Phase 1 | 2 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT01878617 | A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma | active not recruiting | Phase 2 | 660 | St. Jude Children's Research HospitalOTHER | 4 | Nov 13, 2025 | clinicaltrials |
| NCT06521567 | A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer | active not recruiting | Phase 1 / Phase 2 | 83 | GlaxoSmithKlineINDUSTRY | 6 | Nov 12, 2025 | clinicaltrials |
| NCT04365374 | Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study) | active not recruiting | Phase 3 | 230 | GT Medical Technologies, Inc.INDUSTRY | 1 | Oct 7, 2025 | clinicaltrials |
| NCT07200687 | Effects of Combined Music Therapy and Occupational Therapy on Motor and Physiological Parameters in Children With Neurological Impairments: A Non-Randomized Controlled Trial | active not recruiting | N/A | 18 | Armakola FilomeniOTHER | 1 | Oct 7, 2025 | clinicaltrials |
| NCT05634707 | Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) | active not recruiting | Early Phase 1 | 10 | Duke UniversityOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT05404308 | Interest of a Weekly Consultation by a Medical Electro Radiology Manipulator (MERM) in Addition to the Follow-up by the Radiotherapist to Improve the Collection of Radio-induced Toxicities in Patients Undergoing Proton Therapy(MERMOSE) | active not recruiting | N/A | 92 | Centre Francois BaclesseOTHER | 1 | Sep 17, 2025 | clinicaltrials |
| NCT06020066 | SRS for NSCLC With Oligo-residual Intracranial Disease After First-line 3rd Generation EGFR-TKI | active not recruiting | Phase 2 | 202 | Fudan UniversityOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT07165262 | Effect of Different Anesthetic Drugs on Electrocorticography (ECOG).(ECOG-Anaes) | active not recruiting | Phase 3 | 88 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Sep 10, 2025 | clinicaltrials |
| NCT07122752 | Feasibility and Outcomes of 3D-printed External Cranial Orthosis After Craniectomy | active not recruiting | — | 32 | Tan Tock Seng HospitalOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT01843413 | Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases | active not recruiting | Phase 1 | 33 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 20, 2025 | clinicaltrials |
| NCT03893487 | Fimepinostat in Treating Brain Tumors in Children and Young Adults(PNOC016) | active not recruiting | Early Phase 1 | 30 | Sabine Mueller, MD, PhDOTHER | 2 | Jul 11, 2025 | clinicaltrials |
| NCT04785521 | Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery | active not recruiting | — | 100 | IRCCS San RaffaeleOTHER | 1 | Jun 11, 2025 | clinicaltrials |
| NCT05179824 | Tempus Priority Study: A Pan-tumor Observational Study | active not recruiting | — | 1,000 | Tempus AIINDUSTRY | 1 | May 6, 2025 | clinicaltrials |
| NCT00147056 | MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors | active not recruiting | N/A | 10 | InSightecINDUSTRY | 1 | May 1, 2025 | clinicaltrials |
| NCT01473485 | ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors | active not recruiting | N/A | 10 | InSightecINDUSTRY | 1 | May 1, 2025 | clinicaltrials |
| NCT02343991 | Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound | active not recruiting | N/A | 10 | InSightecINDUSTRY | 1 | May 1, 2025 | clinicaltrials |
| NCT05793489 | Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin | active not recruiting | N/A | 44 | Istituto Clinico HumanitasOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06557187 | Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC | active not recruiting | N/A | 40 | Yatian LiuOTHER | 1 | Apr 18, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Mar 31, 2026source: clinicaltrials