Precursor Condition
High Grade Intraepithelial Neoplasia
CI-CAN-00000992Explore in graph →
Precursor22 active trials
- NCIt
- C7348
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Precursor Condition
CI-CAN-00000992Explore in graph →
Clinical trials
102 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05282745 | A Multicenter Cohort Study of HPV Viral Load in Predicting the Postoperative Recurrence of HSIL | unknown | — | 4,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT05283239 | Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection | unknown | — | 1,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Nov 18, 2023 |
| clinicaltrials |
| NCT05405270 | Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment(PRedICT-TOPIC) | recruiting | — | 410 | Catharina Ziekenhuis EindhovenOTHER | 1 | Sep 11, 2023 | clinicaltrials |
| NCT03180684 | Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) | completed | Phase 2 | 33 | Inovio PharmaceuticalsINDUSTRY | 1 | Aug 25, 2023 | clinicaltrials |
| NCT03185013 | REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)(REVEAL 1) | completed | Phase 3 | 201 | Inovio PharmaceuticalsINDUSTRY | 19 | Jul 27, 2023 | clinicaltrials |
| NCT05120167 | Strategies for Endocervical Canal Investigation in Women With Abnormal Screening Cytology and Negative Colposcopy | completed | N/A | 288 | Cirbia Silva Campos TeixeiraOTHER | 1 | Jul 27, 2023 | clinicaltrials |
| NCT05584332 | A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females | terminated | Phase 3 | 3,131 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Jul 21, 2023 | clinicaltrials |
| NCT02238938 | Piecemeal Versus En Bloc Resection of Large Rectal Adenomas(PERLA) | terminated | N/A | 110 | Universitätsklinikum Hamburg-EppendorfOTHER | 2 | Jun 29, 2023 | clinicaltrials |
| NCT05851079 | Accurate Screening and Prevention of Cervical Lesions-- Development of Accurate Screening Methods for Cervical Lesions | unknown | — | 15,000 | Women's Hospital School Of Medicine Zhejiang UniversityOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT03064087 | Validation of Human Papillomavirus Assays and Collection Devices for Self-samples and Urine Samples(VALHUDES) | active not recruiting | — | 500 | Marc ArbynOTHER_GOV | 1 | Mar 29, 2023 | clinicaltrials |
| NCT05745597 | Prognostic Study of HPV Virus Integration in Women With HSIL | unknown | — | 1,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Feb 27, 2023 | clinicaltrials |
| NCT04191967 | Thermocoagulation for Treatment of Precancerous Cervical Lesions | completed | N/A | 379 | University of California, San FranciscoOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT04312737 | Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma Virus(EU-VALHUDES) | completed | — | 600 | Hiantis SrlINDUSTRY | 3 | Jan 6, 2023 | clinicaltrials |
| NCT05631015 | Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals | unknown | — | 2,000 | Xiuli ZuoOTHER | 1 | Nov 30, 2022 | clinicaltrials |
| NCT04484415 | Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL)(APRICITY) | unknown | Phase 3 | 402 | Asieris MediTech (Hong Kong) Co., Ltd.INDUSTRY | 1 | Aug 12, 2022 | clinicaltrials |
| NCT02529930 | An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) | completed | Phase 1 / Phase 2 | 34 | Nykode Therapeutics ASAINDUSTRY | 1 | Jul 13, 2022 | clinicaltrials |
| NCT03113942 | Study of Pomalidomide in Anal Cancer Precursors(SPACE) | unknown | Phase 2 | 26 | Kirby InstituteOTHER_GOV | 1 | Mar 31, 2022 | clinicaltrials |
| NCT04425291 | Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,680 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Feb 25, 2022 | clinicaltrials |
| NCT04910802 | Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden | recruiting | Phase 4 | 150,000 | Miriam ElfströmOTHER_GOV | 1 | Sep 16, 2021 | clinicaltrials |
| NCT02354534 | Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3) | completed | Phase 1 | 30 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Apr 28, 2021 | clinicaltrials |
| NCT03937791 | Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions | terminated | Phase 2 | 1 | National Cancer Institute (NCI)NIH | 1 | Apr 13, 2021 | clinicaltrials |
| NCT03233412 | Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions | completed | Phase 2 | 90 | Barretos Cancer HospitalOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT04647981 | Diagnostic Performance Evaluation Study of the Xpert® Bladder Cancer Monitor Test.(Xpert Bladder) | completed | — | 320 | Clinique Beau SoleilOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT03697226 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection. | completed | Phase 1 | 8 | Antiva BiosciencesINDUSTRY | 1 | Jan 13, 2021 | clinicaltrials |
| NCT00503581 | Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia | terminated | Phase 2 | 9 | Gynecologic Oncology GroupNETWORK | 1 | Nov 3, 2020 | clinicaltrials |
| NCT01550783 | Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening | completed | N/A | 1,335 | University of WashingtonOTHER | 1 | Jul 31, 2020 | clinicaltrials |
| NCT02185599 | IMproved PRactice Outcomes and Value Excellence in Colposcopy(IMPROVE-COLPO) | completed | — | 7,555 | DySIS Medical Inc.INDUSTRY | 1 | Mar 13, 2020 | clinicaltrials |
| NCT03274206 | A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3) | unknown | Phase 2 | 126 | BioLeaders CorporationINDUSTRY | 1 | Feb 7, 2020 | clinicaltrials |
| NCT03676101 | Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 1 | 90 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT02067468 | Optimal Strategy for the Management of ASCUS Cytology in Health Care Services of Medellin, Colombia(ASCUS-COL) | completed | N/A | 2,661 | Universidad de AntioquiaOTHER | 1 | Sep 19, 2019 | clinicaltrials |
| NCT03677960 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | terminated | Phase 1 | 6 | Antiva BiosciencesINDUSTRY | 2 | Jul 24, 2019 | clinicaltrials |
| NCT03239223 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 16 | Antiva BiosciencesINDUSTRY | 2 | Jul 10, 2019 | clinicaltrials |
| NCT03961178 | A Cohort Study for the Following up of Conization | unknown | — | 10,000 | Lei LiOTHER | 1 | Jun 20, 2019 | clinicaltrials |
| NCT03202992 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 57 | Antiva BiosciencesINDUSTRY | 2 | Feb 7, 2019 | clinicaltrials |
| NCT03469531 | Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer | unknown | Phase 2 | 100 | Zhujiang HospitalOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT03141463 | Vvax001 Cancer Vaccine in (Pre) Malignant Cervical Lesions | completed | Phase 1 | 12 | University Medical Center GroningenOTHER | 1 | May 3, 2018 | clinicaltrials |
| NCT01709773 | Focal Ablation of Cervical Precancer | completed | N/A | 20 | University of California, San FranciscoOTHER | 1 | Feb 20, 2018 | clinicaltrials |
| NCT03366493 | The Study of Folate Receptor-Mediated Staining Solution (FRD™) In Cervical Lesion Detection | unknown | Phase 3 | 200 | GY Highland Biotech LLCINDUSTRY | 1 | Dec 8, 2017 | clinicaltrials |
| NCT03357991 | E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM(ELAVI-67) | unknown | — | 355 | Hospital Universitari de BellvitgeOTHER | 1 | Dec 7, 2017 | clinicaltrials |
| NCT03302858 | A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand | unknown | Phase 2 | 70 | Stephen E. GoldstoneOTHER | 1 | Oct 5, 2017 | clinicaltrials |
| NCT00081263 | Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia | completed | Phase 2 | 130 | Gynecologic Oncology GroupNETWORK | 1 | Sep 15, 2017 | clinicaltrials |
| NCT02811367 | The HPV Self-test as a Test of Cure in Madagascar | completed | N/A | 117 | University Hospital, GenevaOTHER | 1 | Oct 17, 2016 | clinicaltrials |
| NCT02189161 | A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia | completed | N/A | 10 | Medtronic - MITGINDUSTRY | 1 | Jul 14, 2016 | clinicaltrials |
| NCT02418494 | Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions | completed | — | 85 | AIDS Malignancy ConsortiumNETWORK | 1 | Jun 9, 2016 | clinicaltrials |
| NCT01366742 | Natural History of HPV From Infection to Neoplasia in Adolescents and Young Women | completed | — | 900 | University of California, Los AngelesOTHER | 1 | May 17, 2016 | clinicaltrials |
| NCT02220192 | An Alternative Treatment for Cervical Intraepithelial Neoplasia Using the Focal Loop Electrosurgical Excision Procedure | completed | N/A | 11 | University of Alabama at BirminghamOTHER | 1 | Apr 6, 2016 | clinicaltrials |
| NCT01733719 | Barrett&Apos;s Intervention for Dysplasia by Endoscopy(BRIDE) | completed | N/A | 76 | University Hospitals, LeicesterOTHER | 1 | Mar 11, 2016 | clinicaltrials |
| NCT01871636 | ESD Versus EMR for Treatment of Early Barrett's Adenocarcinoma | completed | N/A | 40 | Evangelisches Krankenhaus DüsseldorfOTHER | 1 | Sep 9, 2015 | clinicaltrials |
| NCT02406352 | Multispectral Digital Colposcope With Probe for Detection of Cervical Intraepithelial Neoplasia(MDCwProbe) | unknown | N/A | 618 | Brookdale University Hospital Medical CenterOTHER | 1 | Apr 10, 2015 | clinicaltrials |
| NCT01695018 | Early Diagnosis of Oral Cancer by Detecting p16 Methylation | completed | — | 180 | Peking UniversityOTHER | 0 | Sep 25, 2014 | clinicaltrials |
Data updated 22 days agoSource updated Nov 18, 2023source: clinicaltrials