Precursor Condition
High Grade Intraepithelial Neoplasia
CI-CAN-00000992Explore in graph →
Precursor22 active trials
- NCIt
- C7348
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Precursor Condition
CI-CAN-00000992Explore in graph →
Clinical trials
102 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06949800 | CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial | recruiting | Phase 2 | 90 | University of California, San FranciscoOTHER | 2 | Sep 15, 2026 | clinicaltrials |
| NCT07545746 | Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treatment Outcomes in Women With HIV in Kenya(ASCEND) | not yet recruiting | Phase 2 | 140 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Aug 27, 2026 |
| clinicaltrials |
| NCT03603808 | VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions | completed | Phase 2 | 44 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 8, 2026 | clinicaltrials |
| NCT07454915 | PVX4 for the Treatment of Human Papilloma Virus (HPV)16+ Cervical Dysplasia | recruiting | Phase 2 | 138 | PapiVax Biotech, Inc.OTHER | 2 | May 6, 2026 | clinicaltrials |
| NCT04712851 | Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia | recruiting | Phase 2 | 25 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT04098744 | Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)(ART-CIN_IIB) | recruiting | Phase 2 | 78 | Frantz Viral Therapeutics, LLCINDUSTRY | 1 | Oct 2, 2025 | clinicaltrials |
| NCT06075264 | Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)(ART-VIN IIB) | recruiting | Phase 2 | 27 | Frantz Viral Therapeutics, LLCINDUSTRY | 1 | Aug 14, 2025 | clinicaltrials |
| NCT07095478 | Safety and Efficacy of Oral Artesunate for Pre-cervical Cancer(NeoART-CIN) | not yet recruiting | Phase 2 | 28 | Metanoic Health Ltd.INDUSTRY | 1 | Jul 31, 2025 | clinicaltrials |
| NCT05104099 | Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia(PhotodiVIN) | completed | Phase 2 | 17 | Institut de Cancérologie de LorraineOTHER | 1 | Jul 24, 2025 | clinicaltrials |
| NCT03267680 | IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3 | terminated | Phase 2 | 10 | University of Southern CaliforniaOTHER | 1 | Apr 13, 2025 | clinicaltrials |
| NCT06273553 | A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3 | not yet recruiting | Phase 1 / Phase 2 | 39 | RinuaGene Biotechnology Co., Ltd.INDUSTRY | 0 | Feb 22, 2024 | clinicaltrials |
| NCT03180684 | Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) | completed | Phase 2 | 33 | Inovio PharmaceuticalsINDUSTRY | 1 | Aug 25, 2023 | clinicaltrials |
| NCT02529930 | An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) | completed | Phase 1 / Phase 2 | 34 | Nykode Therapeutics ASAINDUSTRY | 1 | Jul 13, 2022 | clinicaltrials |
| NCT03113942 | Study of Pomalidomide in Anal Cancer Precursors(SPACE) | unknown | Phase 2 | 26 | Kirby InstituteOTHER_GOV | 1 | Mar 31, 2022 | clinicaltrials |
| NCT03937791 | Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions | terminated | Phase 2 | 1 | National Cancer Institute (NCI)NIH | 1 | Apr 13, 2021 | clinicaltrials |
| NCT03233412 | Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions | completed | Phase 2 | 90 | Barretos Cancer HospitalOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00503581 | Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia | terminated | Phase 2 | 9 | Gynecologic Oncology GroupNETWORK | 1 | Nov 3, 2020 | clinicaltrials |
| NCT03274206 | A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3) | unknown | Phase 2 | 126 | BioLeaders CorporationINDUSTRY | 1 | Feb 7, 2020 | clinicaltrials |
| NCT03469531 | Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer | unknown | Phase 2 | 100 | Zhujiang HospitalOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT03302858 | A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand | unknown | Phase 2 | 70 | Stephen E. GoldstoneOTHER | 1 | Oct 5, 2017 | clinicaltrials |
| NCT00081263 | Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia | completed | Phase 2 | 130 | Gynecologic Oncology GroupNETWORK | 1 | Sep 15, 2017 | clinicaltrials |
| NCT00072540 | S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of the Cervix | withdrawn | Phase 2 | 0 | SWOG Cancer Research NetworkNETWORK | 0 | Nov 8, 2013 | clinicaltrials |
| NCT00091130 | SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells | completed | Phase 2 | 139 | National Cancer Institute (NCI)NIH | 1 | Jun 3, 2013 | clinicaltrials |
Data updated 15 days agoSource updated Sep 15, 2026source: clinicaltrials