Precursor Condition
High Grade Intraepithelial Neoplasia
CI-CAN-00000992Explore in graph →
Precursor22 active trials
- NCIt
- C7348
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Precursor Condition
CI-CAN-00000992Explore in graph →
Clinical trials
102 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03603808 | VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions | completed | Phase 2 | 44 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 8, 2026 | clinicaltrials |
| NCT07563166 | Clinicopathologic Features and Staging Risk Factors of Early-Onset Colorectal Cancer | completed | — | 500 | Run-hua LiOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT04423679 |
| The Selfie Study- Assessing Novel Markers for Cervical Cancer Screening From Self-collected Samples(SELFIE) |
| completed |
| — |
| 294 |
| George Washington UniversityOTHER |
| 1 |
| Mar 6, 2026 |
| clinicaltrials |
| NCT03284866 | HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV(COVENANT) | completed | Phase 3 | 536 | AIDS Malignancy ConsortiumNETWORK | 5 | Jan 28, 2026 | clinicaltrials |
| NCT04788849 | Extended VALidation of HUman Papillomavirus Assays and Collection DEvices for HPV Testing on Self-samples(Ext-VALHUDES) | completed | — | 300 | University of Milano BicoccaOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT05104099 | Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia(PhotodiVIN) | completed | Phase 2 | 17 | Institut de Cancérologie de LorraineOTHER | 1 | Jul 24, 2025 | clinicaltrials |
| NCT02059499 | Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions | completed | Phase 3 | 91 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 23, 2025 | clinicaltrials |
| NCT03196180 | Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia | completed | Early Phase 1 | 13 | National Cancer Institute (NCI)NIH | 1 | Apr 8, 2025 | clinicaltrials |
| NCT04276935 | Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions | completed | — | 20 | AIDS Malignancy ConsortiumNETWORK | 1 | Mar 7, 2025 | clinicaltrials |
| NCT06316882 | Gastric Cancer Endoscopic Screening in an Intermediate-risk Country - ROGCAS, a Dual-centre Pilot Program(ROGCAS) | completed | — | 349 | Unidade Local De Saúde Do Norte AlentejanoOTHER | 1 | Feb 27, 2025 | clinicaltrials |
| NCT06258564 | The Adjuvant Effect of HPV Vaccination on Recurrence of Cervical Precancer or Carcinoma in Women Undergoing Conization | completed | — | 12,000 | Charles University, Czech RepublicOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT05717621 | Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)(DelVIN) | completed | Phase 1 | 29 | ViMREX GmbHINDUSTRY | 1 | Feb 11, 2025 | clinicaltrials |
| NCT03721978 | REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) | completed | Phase 3 | 203 | Inovio PharmaceuticalsINDUSTRY | 10 | Oct 17, 2024 | clinicaltrials |
| NCT05362955 | 5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa | completed | Phase 1 | 12 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Aug 23, 2024 | clinicaltrials |
| NCT02135419 | Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions(ANCHOR) | completed | Phase 3 | 4,446 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 26, 2024 | clinicaltrials |
| NCT04055142 | Clinical Trial for Evaluating the Efficacy and Safety of Electrocoagulation vs Topic Sinecatechins vs Topic Cidofovir Within the Treatment to High-grade Anal Intraepithelial Neoplasia in HIV Homosexual Males(TreatAIN) | completed | Phase 3 | 108 | Hospital Universitari Vall d'Hebron Research InstituteOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT05372016 | Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,200 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Nov 24, 2023 | clinicaltrials |
| NCT03180684 | Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) | completed | Phase 2 | 33 | Inovio PharmaceuticalsINDUSTRY | 1 | Aug 25, 2023 | clinicaltrials |
| NCT03185013 | REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)(REVEAL 1) | completed | Phase 3 | 201 | Inovio PharmaceuticalsINDUSTRY | 19 | Jul 27, 2023 | clinicaltrials |
| NCT05120167 | Strategies for Endocervical Canal Investigation in Women With Abnormal Screening Cytology and Negative Colposcopy | completed | N/A | 288 | Cirbia Silva Campos TeixeiraOTHER | 1 | Jul 27, 2023 | clinicaltrials |
| NCT04191967 | Thermocoagulation for Treatment of Precancerous Cervical Lesions | completed | N/A | 379 | University of California, San FranciscoOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT04312737 | Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma Virus(EU-VALHUDES) | completed | — | 600 | Hiantis SrlINDUSTRY | 3 | Jan 6, 2023 | clinicaltrials |
| NCT02529930 | An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) | completed | Phase 1 / Phase 2 | 34 | Nykode Therapeutics ASAINDUSTRY | 1 | Jul 13, 2022 | clinicaltrials |
| NCT04425291 | Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,680 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Feb 25, 2022 | clinicaltrials |
| NCT02354534 | Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3) | completed | Phase 1 | 30 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Apr 28, 2021 | clinicaltrials |
| NCT03233412 | Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions | completed | Phase 2 | 90 | Barretos Cancer HospitalOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT04647981 | Diagnostic Performance Evaluation Study of the Xpert® Bladder Cancer Monitor Test.(Xpert Bladder) | completed | — | 320 | Clinique Beau SoleilOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT03697226 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection. | completed | Phase 1 | 8 | Antiva BiosciencesINDUSTRY | 1 | Jan 13, 2021 | clinicaltrials |
| NCT01550783 | Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening | completed | N/A | 1,335 | University of WashingtonOTHER | 1 | Jul 31, 2020 | clinicaltrials |
| NCT02185599 | IMproved PRactice Outcomes and Value Excellence in Colposcopy(IMPROVE-COLPO) | completed | — | 7,555 | DySIS Medical Inc.INDUSTRY | 1 | Mar 13, 2020 | clinicaltrials |
| NCT03676101 | Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 1 | 90 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT02067468 | Optimal Strategy for the Management of ASCUS Cytology in Health Care Services of Medellin, Colombia(ASCUS-COL) | completed | N/A | 2,661 | Universidad de AntioquiaOTHER | 1 | Sep 19, 2019 | clinicaltrials |
| NCT03239223 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 16 | Antiva BiosciencesINDUSTRY | 2 | Jul 10, 2019 | clinicaltrials |
| NCT03202992 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 57 | Antiva BiosciencesINDUSTRY | 2 | Feb 7, 2019 | clinicaltrials |
| NCT03141463 | Vvax001 Cancer Vaccine in (Pre) Malignant Cervical Lesions | completed | Phase 1 | 12 | University Medical Center GroningenOTHER | 1 | May 3, 2018 | clinicaltrials |
| NCT01709773 | Focal Ablation of Cervical Precancer | completed | N/A | 20 | University of California, San FranciscoOTHER | 1 | Feb 20, 2018 | clinicaltrials |
| NCT00081263 | Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia | completed | Phase 2 | 130 | Gynecologic Oncology GroupNETWORK | 1 | Sep 15, 2017 | clinicaltrials |
| NCT02811367 | The HPV Self-test as a Test of Cure in Madagascar | completed | N/A | 117 | University Hospital, GenevaOTHER | 1 | Oct 17, 2016 | clinicaltrials |
| NCT02189161 | A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia | completed | N/A | 10 | Medtronic - MITGINDUSTRY | 1 | Jul 14, 2016 | clinicaltrials |
| NCT02418494 | Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions | completed | — | 85 | AIDS Malignancy ConsortiumNETWORK | 1 | Jun 9, 2016 | clinicaltrials |
| NCT01366742 | Natural History of HPV From Infection to Neoplasia in Adolescents and Young Women | completed | — | 900 | University of California, Los AngelesOTHER | 1 | May 17, 2016 | clinicaltrials |
| NCT02220192 | An Alternative Treatment for Cervical Intraepithelial Neoplasia Using the Focal Loop Electrosurgical Excision Procedure | completed | N/A | 11 | University of Alabama at BirminghamOTHER | 1 | Apr 6, 2016 | clinicaltrials |
| NCT01733719 | Barrett&Apos;s Intervention for Dysplasia by Endoscopy(BRIDE) | completed | N/A | 76 | University Hospitals, LeicesterOTHER | 1 | Mar 11, 2016 | clinicaltrials |
| NCT01871636 | ESD Versus EMR for Treatment of Early Barrett's Adenocarcinoma | completed | N/A | 40 | Evangelisches Krankenhaus DüsseldorfOTHER | 1 | Sep 9, 2015 | clinicaltrials |
| NCT01695018 | Early Diagnosis of Oral Cancer by Detecting p16 Methylation | completed | — | 180 | Peking UniversityOTHER | 0 | Sep 25, 2014 | clinicaltrials |
| NCT00091130 | SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells | completed | Phase 2 | 139 | National Cancer Institute (NCI)NIH | 1 | Jun 3, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Jul 8, 2026source: clinicaltrials