Clinical trial · Observational
A Cohort Study for the Following up of Conization
Oncologic and Obstetric Outcomes After Conization for Uterine Cervical Lesion: A Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is to investigate the oncologic and obstetric outcomes in patients with conization for uterine cervical lesions from January 1, 2000 to January 1, 2019 in Peking Union Medical College Hospital. The primary objectives consist of following: 1. The cumulative incidences of precancerous lesions and cancers of lower genital tract in patients who accepted conization for high grade intraepithelial neoplasia (HSIL), carcinoma in situ and stage IA1 cancer (FIGO 2009) 2. The cumulative pregnancy rates in patients sparing the fertility The secondary objectives consist of following: 1. The effects of surgical protocols (modified Sturmdorf method and "8" figure suture) and energy equipment (cold knife and monopolar electrical cautery) on the oncologic and obstetric outcomes, and on the histological components. 2. A full description of histological components of the conization specimens 3. The cytological and virus outcomes after conization, based on the thin prep liquid-based cytology test (TCT) and high-risk human papillomavirus (HPV) testing
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Conization | — | UNRESOLVED | — |
| Fertility | — | UNRESOLVED | — |
| High Grade Intraepithelial Neoplasia | High Grade Intraepithelial Neoplasia | ONTOLOGY_EXACT | 0.98 |
| Human Papillomavirus Infection | — | UNRESOLVED | — |
| Precancerous Lesions | — | UNRESOLVED | — |
| Pregnancy | — | UNRESOLVED | — |
| Uterine Cervical Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| High-risk HPV | Diagnostic Test | — | UNRESOLVED |
| TCT | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- The cumulative incidences of precancerous lesions or cancers
- timeFrame
- Five years
- description
- The cumulative incidences of precancerous lesions and cancers of lower genital track in patients who accepted conization for high grade intraepithelial neoplasia (HSIL), carcinoma in situ and stage IA1 cancer (FIGO 2009)
- measure
- The cumulative pregnancy rates
- timeFrame
- Five years
- description
- The cumulative pregnancy rates in patients sparing the fertility
Secondary outcomes (4)
- measure
- The cytological results after conization
- timeFrame
- Five years
- description
- The cytological after conization based on the thin prep liquid-based cytology test (TCT)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Accepting conization in the study center * Aged 18 years or older Exclusion Criteria: * Not meeting any of the inclusion criteria
References
Publications (0)
Data not yet available