Subtype
Hepatocellular Carcinoma
CI-CAN-00002853HCC · LIHCExplore in graph →
693 active trials13 approved drugs9 evidence items
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Subtype
CI-CAN-00002853HCC · LIHCExplore in graph →
Clinical trials
3,126 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (357)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06796114 | Identification of Innovative Biomarkers to Predict Outcomes in Hepatocellular Carcinoma Treated With Tremelimumab and Durvalumab(PREDICT-HCC) | recruiting | N/A | 120 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07521852 | A Phase IIa, Single-arm, Open-label Clinical Study to Evaluate the Efficacy, Safety and PK of CVM-1118 in Combination With Sintilimab and TACE in Participants With Incurable/Non-metastatic HCC | recruiting | Phase 2 | 40 | TaiRx, Inc.INDUSTRY |
| 1 |
| Jul 23, 2026 |
| clinicaltrials |
| NCT04892810 | Immunomonitoring of Interventional Radiology Procedures in the Management of Hepatocellular Carcinoma(PAI²HCC) | completed | — | 20 | University Hospital, GrenobleOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT05208762 | A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors | recruiting | Phase 1 | 714 | Seagen, a wholly owned subsidiary of PfizerINDUSTRY | 11 | Jul 22, 2026 | clinicaltrials |
| NCT04930315 | SHR-1210 Combined With Apatinib Mesylate in the Perioperative Therapy for Hepatocellular Carcinoma(CAPT) | completed | Phase 2 | 78 | Zhejiang UniversityOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT07690683 | Patients With Hepatocellular Carcinoma (HCC)(FORCE) | not yet recruiting | N/A | 52 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT07716345 | Inter-Individual Tumor Heterogeneity on 3D-MRE for Predicting Response to Conversion Therapy in Liver Cancer | not yet recruiting | — | 100 | Second Affiliated Hospital of Xi'an Jiaotong UniversityOTHER | 0 | Jul 21, 2026 | clinicaltrials |
| NCT05128032 | Pressure-enabled Delivery in Radioembolization (TriNav Study)(PEDIR) | completed | N/A | 29 | Massachusetts General HospitalOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT05194293 | Regorafenib and Durvalumab for the Treatment of High-Risk Liver Cancer | active not recruiting | Phase 2 | 4 | Academic and Community Cancer Research UnitedOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT07713290 | A Phase 1b Study of GKL-006 Injection in Patients With Unresectable Hepatocellular Carcinoma | active not recruiting | Phase 1 | 6 | Beijing Gene Key Life Technology Co., LtdINDUSTRY | 1 | Jul 20, 2026 | clinicaltrials |
| NCT07714317 | Phase Ib/II Multicenter Randomized Control Study of Peri-operative Treatment With Combination of CTLA-4, PD-1 Antibodies and Bevacizumab in Resectable HCC (Prophet) | not yet recruiting | Phase 1 / Phase 2 | 90 | Shanghai Zhongshan HospitalOTHER | 0 | Jul 20, 2026 | clinicaltrials |
| NCT04792801 | PET TDM FDG-Choline as a Decision-making Tool for Routine Care on the Liver Transplant List for HCC(TEP CARE) | active not recruiting | — | 108 | University Hospital, LilleOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT05078047 | Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO(MOIO) | active not recruiting | Phase 3 | 646 | UNICANCEROTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT05148572 | Prospective Cohort Study of Changes in Circulatory MicroRNA of Resected Hepatocellular Carcinoma(PROSECT) | active not recruiting | — | 101 | National Cancer Centre, SingaporeOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT06796803 | Camrelizumab Combined With Rivoceranib and Hepatic Arterial Infusion Chemotherapy (HAIC) as Conversion Therapy for Potentially Resectable Hepatocellular Carcinoma(HCC) | recruiting | Phase 2 / Phase 3 | 398 | Shanghai Zhongshan HospitalOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT05092373 | Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax | recruiting | Phase 1 | 43 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT05705492 | Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer | recruiting | Phase 2 | 66 | OHSU Knight Cancer InstituteOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT07707661 | Application of Super-Resolution Ultrasound (SRUS) in Liver Tumor(SRUS) | not yet recruiting | — | 350 | Eastern Hepatobiliary Surgery HospitalOTHER | 0 | Jul 16, 2026 | clinicaltrials |
| NCT07709299 | Safety and Feasibility of CIK Cell Therapy in HCC After Tumor Resection | not yet recruiting | Early Phase 1 | 6 | Royan InstituteOTHER_GOV | 1 | Jul 16, 2026 | clinicaltrials |
| NCT03778957 | A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma(EMERALD-1) | active not recruiting | Phase 3 | 724 | AstraZenecaINDUSTRY | 18 | Jul 15, 2026 | clinicaltrials |
| NCT04374877 | Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors | completed | Phase 1 | 145 | Coherus Oncology, Inc.INDUSTRY | 3 | Jul 15, 2026 | clinicaltrials |
| NCT06478719 | To Evaluate Safety and Efficacy of FB-1603 in Hepatocellular Carcinoma Patient Receiving Transarterial Chemoembolization | recruiting | Phase 1 / Phase 2 | 120 | Febico Biomedical Corp.INDUSTRY | 1 | Jul 15, 2026 | clinicaltrials |
| NCT06679985 | A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma | active not recruiting | Phase 2 | 72 | Coherus Oncology, Inc.INDUSTRY | 6 | Jul 15, 2026 | clinicaltrials |
| NCT07010497 | A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular Carcinoma(IAPETUS) | recruiting | Phase 2 | 33 | Asan Medical CenterOTHER | 1 | Jul 15, 2026 | clinicaltrials |
| NCT07704203 | Preoperative 3D Magnetic Resonance Elastography for Predicting Surgical Risk in Patients Undergoing Hepatectomy | not yet recruiting | — | 150 | Second Affiliated Hospital of Xi'an Jiaotong UniversityOTHER | 0 | Jul 15, 2026 | clinicaltrials |
| NCT07704216 | Peritumoral MRE Stiffness for Predicting Resection Margin Status and Recurrence in Liver Cancer | not yet recruiting | — | 150 | Second Affiliated Hospital of Xi'an Jiaotong UniversityOTHER | 0 | Jul 15, 2026 | clinicaltrials |
| NCT07704489 | San Raffaele Registry on Liver Cancer | recruiting | — | 4,000 | IRCCS San RaffaeleOTHER | 1 | Jul 15, 2026 | clinicaltrials |
| NCT07705074 | FAPI PET Imaging - An Exploratory Study(FAPIPET) | not yet recruiting | Phase 1 / Phase 2 | 770 | Martin HuellnerOTHER | 1 | Jul 15, 2026 | clinicaltrials |
| NCT01171651 | A Study of Pexa-Vec (JX-594) Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma | completed | Phase 2 | 25 | Jennerex BiotherapeuticsINDUSTRY | 1 | Jul 14, 2026 | clinicaltrials |
| NCT05669339 | AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma | recruiting | Phase 2 | 12 | University of FloridaOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT07703735 | Survival and Recurrence After ABO-Incompatible Living Donor Liver Transplantation for Hepatocellular Carcinoma(HCC) | enrolling by invitation | — | 371 | Seoung Hoon KimOTHER_GOV | 0 | Jul 14, 2026 | clinicaltrials |
| NCT04723004 | Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC | completed | Phase 3 | 326 | Shanghai Junshi Bioscience Co., Ltd.OTHER | 2 | Jul 13, 2026 | clinicaltrials |
| NCT05301842 | Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC(EMERALD-3) | active not recruiting | Phase 3 | 760 | AstraZenecaINDUSTRY | 22 | Jul 13, 2026 | clinicaltrials |
| NCT07700082 | HCC-MPDS Multimodal Deep Learning Prognostic Model for Resectable HCC(HCC-MPDS) | completed | — | 555 | Anhui Provincial HospitalOTHER_GOV | 1 | Jul 13, 2026 | clinicaltrials |
| NCT05199259 | Multi-analyte Blood Test Clinical Trial(LIVER-1) | recruiting | — | 1,200 | Helio GenomicsINDUSTRY | 1 | Jul 10, 2026 | clinicaltrials |
| NCT06096779 | A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis(Kirros) | active not recruiting | Phase 2 | 30 | Genentech, Inc.INDUSTRY | 2 | Jul 10, 2026 | clinicaltrials |
| NCT04605796 | A Single-arm, Open-label, Multi-center Phase II Clinical Study to Evaluate the Safety and Efficacy of Toripalimab Injection (JS001) Combined With Bevacizumab as the First-line Therapy for Advanced Hepatocellular Carcinoma (HCC) | completed | Phase 2 | 54 | Shanghai Junshi Bioscience Co., Ltd.OTHER | 1 | Jul 9, 2026 | clinicaltrials |
| NCT05864105 | PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma | completed | Phase 2 | 35 | Biotheus Inc.INDUSTRY | 1 | Jul 9, 2026 | clinicaltrials |
| NCT07562763 | Estimation and Prediction of Individual Benefit From Postoperative Adjuvant Transcatheter Arterial Chemoembolization For Patients With Hepatocellular Carcinoma(HCC) | completed | — | 1,005 | Anhui Provincial HospitalOTHER_GOV | 1 | Jul 9, 2026 | clinicaltrials |
| NCT01387555 | A Phase 2b Study of Modified Vaccinia Virus to Treat Patients Advanced Liver Cancer Who Failed Sorafenib(TRAVERSE) | completed | Phase 2 | 129 | Jennerex BiotherapeuticsINDUSTRY | 7 | Jul 8, 2026 | clinicaltrials |
| NCT03519997 | A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma | completed | Phase 2 | 35 | David HsiehOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT05705791 | Clinical Investigation Evaluating Safety and Efficacy of Selective Intra-arterial 166Holmium Radiation Therapy in Combination With Atezolizumab and Bevacizumab for Non Resectable Hepatocellular Carcinoma(HOLMBRAVE) | terminated | N/A | 10 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT07018947 | Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC(ASPIRE) | recruiting | Phase 2 | 90 | Fundacion Clinic per a la Recerca BiomédicaOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT07685548 | AI-Driven Tumor Response Evaluation for Solid Tumors | not yet recruiting | — | 6,120 | Shanghai Zhongshan HospitalOTHER | 0 | Jul 8, 2026 | clinicaltrials |
| NCT06342414 | An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer(ELUCIDATE) | recruiting | — | 400 | City of Hope Medical CenterOTHER | 2 | Jul 7, 2026 | clinicaltrials |
| NCT07224750 | A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer(MiGIC) | recruiting | — | 1,000 | City of Hope Medical CenterOTHER | 1 | Jul 7, 2026 | clinicaltrials |
| NCT07675187 | HCC Risk and Monitoring in Patients With Type 2 Diabetes(GAAD-DM) | not yet recruiting | N/A | 2,400 | National Taiwan University HospitalOTHER | 1 | Jul 7, 2026 | clinicaltrials |
| NCT07687758 | Non-Invasive Risk Stratification for Hepatocellular Carcinoma in HCV-Related Compensated Advanced Chronic Liver Disease Following Sustained Virological Response: Validation of the aMAP Score(HCV-aMAP) | completed | — | 571 | Siriraj HospitalOTHER | 1 | Jul 7, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Jul 23, 2026source: clinicaltrials