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CI-CAN-00002836HNSCC · SCCHNExplore in graph →
Clinical trials
1,589 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (247)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07847060 | Hypofractionated Radiotherapy in Older Adults With Head and Neck Squamous Cell Carcinoma | not yet recruiting | N/A | 60 | Assiut UniversityOTHER | 0 | Sep 29, 2026 | clinicaltrials |
| NCT07060261 | Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma | recruiting | N/A | 30 | Case Comprehensive Cancer CenterOTHER | 1 | Sep 22, 2026 | clinicaltrials |
| NCT07823309 |
| Quad Shot Versus Split Course Radiotherapy in Incurable Head and Neck Cancer(QSSC-HN) |
| not yet recruiting |
| N/A |
| 40 |
| Instituto Nacional de Cancerologia, ColumbiaOTHER_GOV |
| 0 |
| Sep 16, 2026 |
| clinicaltrials |
| NCT06487403 | HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers(HN-Bio 02) | recruiting | N/A | 40 | University Health Network, TorontoOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07809100 | Tumoral Versus Luminal Microbiome in Head and Neck Squamous Cell Carcinoma(MIC-VADS) | not yet recruiting | N/A | 120 | Centre Hospitalier Sud FrancilienOTHER | 1 | Sep 9, 2026 | clinicaltrials |
| NCT07090070 | Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors(p53 RCT) | recruiting | N/A | 636 | University of British ColumbiaOTHER | 1 | Sep 8, 2026 | clinicaltrials |
| NCT07801235 | HYperfractionated Radiation Therapy Versus Concurrent Chemoradiation for Head and Neck Cancer (HYTC) | recruiting | N/A | 604 | King Hussein Cancer CenterOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT07766226 | Online Sharing for Head & Neck Cancer Support | recruiting | N/A | 120 | West China HospitalOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT07797738 | Prognostic Biomarkers for Patients With Human Papillomavirus (HPV) Positive Oropharyngeal Squamous Cell Carcinoma(OPSCC) | not yet recruiting | N/A | 30 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Sep 1, 2026 | clinicaltrials |
| NCT07784855 | Scheduled IV Fluids in the Supportive Management of Patients Undergoing Chemo-radiotherapy for Head and Neck Cancer | not yet recruiting | N/A | 180 | West Virginia UniversityOTHER | 1 | Aug 25, 2026 | clinicaltrials |
| NCT05707078 | PET/CT Follow up for Head and Neck Squamous Cell Carcinoma(PET Follow) | recruiting | N/A | 600 | Rigshospitalet, DenmarkOTHER | 1 | Aug 12, 2026 | clinicaltrials |
| NCT06915038 | ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx | recruiting | N/A | 120 | Indiana UniversityOTHER | 1 | Aug 11, 2026 | clinicaltrials |
| NCT06630780 | Reduction of Postoperative Radiotherapy in Head and Neck Squamous Cell Carcinoma(REPORT-HNSCC) | recruiting | N/A | 50 | Sun Yat-sen UniversityOTHER | 1 | Aug 7, 2026 | clinicaltrials |
| NCT06085781 | A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers(HN-BIO) | recruiting | N/A | 60 | University Health Network, TorontoOTHER | 1 | Aug 6, 2026 | clinicaltrials |
| NCT07717307 | Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread(ExtentN1) | recruiting | N/A | 80 | Kolhapur Cancer Centre - Cancer Centers of AmericaOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT07726199 | Study Comparing Different Neck Treatment Approaches in Patients With Oral Cancer Without Visible Neck Spread(ExtentN0) | recruiting | N/A | 267 | Kolhapur Cancer Centre - Cancer Centers of AmericaOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT06367257 | App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy | recruiting | N/A | 148 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Jul 31, 2026 | clinicaltrials |
| NCT07241273 | SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer(SELECT-FR) | not yet recruiting | N/A | 128 | UNICANCEROTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT06662058 | Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation | recruiting | N/A | 118 | Emory UniversityOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT07674706 | Evaluating the Optimal Timing of Acupuncture for Managing Chemoradiation-induced Xerostomia in Patients With Head and Neck Cancers | not yet recruiting | N/A | 50 | National University Hospital, SingaporeOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07671573 | Integrated Early-CARE for Head & Neck Cancer.(i-CARE-HN) | not yet recruiting | N/A | 64 | Portuguese Oncology Institute, CoimbraOTHER | 1 | Jun 26, 2026 | clinicaltrials |
| NCT06971848 | Evaluation of Skin Tests in Biotherapy Allergies(ETCABIO) | recruiting | N/A | 70 | University Hospital, AngersOTHER_GOV | 1 | Jun 18, 2026 | clinicaltrials |
| NCT07654647 | Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.(3DFACE) | recruiting | N/A | 30 | Latakia UniversityOTHER | 1 | Jun 17, 2026 | clinicaltrials |
| NCT05889091 | A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment | recruiting | N/A | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT06528353 | Blood Biomarkers Based Screening for HPV-driven OPC(SCREEN-HPV) | not yet recruiting | N/A | 10,000 | UNICANCEROTHER | 0 | May 26, 2026 | clinicaltrials |
| NCT07606638 | Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer Patients | enrolling by invitation | N/A | 98 | Mayo Hospital LahoreOTHER | 1 | May 26, 2026 | clinicaltrials |
| NCT05791149 | Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity(EPSACO) | recruiting | N/A | 60 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | May 13, 2026 | clinicaltrials |
| NCT07579507 | Heterogeneity of Oral Carcinogenesis: From PrEneoplasia to Invasive Squamous Cell Carcinoma(HOPES) | not yet recruiting | N/A | 150 | Centre Leon BerardOTHER | 1 | May 12, 2026 | clinicaltrials |
| NCT06915454 | High-Resolution PET-CT Imaging for Surgical Margin Visualization | recruiting | N/A | 50 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | May 8, 2026 | clinicaltrials |
| NCT06190275 | Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Tumors | recruiting | N/A | 32 | Grit BiotechnologyINDUSTRY | 1 | Apr 24, 2026 | clinicaltrials |
| NCT07546383 | A Study Investigating the Efficacy and Safety of the Combination of Iparomlimab and Tuvonralimab With or Without Chemotherapy in Second-line and Subsequent Treatments for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | recruiting | N/A | 32 | The Second Affiliated Hospital of Hainan Medical UniversityOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07514754 | Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients(GALENOS 2) | recruiting | N/A | 52 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT05047094 | Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC | recruiting | N/A | 48 | Alpha Tau Medical LTD.INDUSTRY | 1 | Apr 6, 2026 | clinicaltrials |
| NCT07507058 | Hypofractionated Radiotherapy for Postoperative Intermediate-Risk Head and Neck Squamous Cell Carcinoma | not yet recruiting | N/A | 60 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 0 | Apr 2, 2026 | clinicaltrials |
| NCT07466810 | Resection and Defect Repair of Oral Cancer Aided by Mixed Reality Technology | not yet recruiting | N/A | 30 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT05919290 | HN-QUEST: A Study of Head and Neck Imaging Biomarkers(HN-Quest) | recruiting | N/A | 173 | University Health Network, TorontoOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT07348887 | Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer(RTL-DART) | recruiting | N/A | 50 | University Health Network, TorontoOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT06336941 | "Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON)(HOUSTON) | recruiting | N/A | 400 | University of PisaOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT05031910 | Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality | recruiting | N/A | 160 | Thomas Jefferson UniversityOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07407205 | Tumor Mutational Burden, Liquid Biopsy, Angiogenic Factors and DCE-MRI Perfusion in HPV-Negative Oropharyngeal Cancer | active not recruiting | N/A | 30 | Institute of Oncology LjubljanaOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07405645 | Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy(MRg-FUS) | recruiting | N/A | 20 | University of VirginiaOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07402525 | Postoperative Radiotherapy for Early-stage Oral Tongue Squamous Cell Carcinoma Patients With Risk Factors: a Prospective, Multicenter, Randomized Controlled, Open-labelled Trial(PORT-ESTER) | recruiting | N/A | 190 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT01473784 | Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck | recruiting | N/A | 600 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT05338905 | Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial | active not recruiting | N/A | 72 | Roswell Park Cancer InstituteOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT04528420 | Optimised Early Management of Squamous Cell Carcinoma of the Head and Neck Cancer(OPTINECK) | recruiting | N/A | 138 | Centre Henri BecquerelOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT05934929 | Contribution of Residual Tumour DNA Testing on the Surgical Bed(MARGINS) | active not recruiting | N/A | 31 | Centre Henri BecquerelOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT04124198 | Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma(QoLATI) | active not recruiting | N/A | 138 | Christian von BuchwaldOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT07190755 | Impact of Patient-Reported Outcomes for Symptom Monitoring in Patients Followed for Head and Neck Squamous Cell Carcinoma (HNSCC)(WEBNECK) | recruiting | N/A | 192 | Centre Henri BecquerelOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT07306546 | Effectiveness of Hydrogen Water Intervention on Acute Oral Inflammation, Oral Microbiota, and Pain Following Free Flap Reconstruction in Patients With Oral Cancer | not yet recruiting | N/A | 36 | Kaohsiung Medical University Chung-Ho Memorial HospitalOTHER | 0 | Dec 29, 2025 | clinicaltrials |
Data updated 15 hours agoSource updated Sep 29, 2026source: clinicaltrials