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CI-CAN-00002836HNSCC · SCCHNExplore in graph →
Clinical trials
1,589 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (247)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04253808 | Feasibility of a Carbohydrate-restricted, High-fat Diet on Head and Neck Squamous Cell Carcinoma Outcomes(CRHF) | completed | N/A | 39 | University of Illinois at Urbana-ChampaignOTHER | 1 | Nov 5, 2021 | clinicaltrials |
| NCT03245736 | Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors. | completed | Phase 2 | 5 | Seagen Inc.INDUSTRY | 2 | Nov 4, 2021 | clinicaltrials |
| NCT01950689 | NIMRAD (A Randomised Placebo-controlled Trial of Synchronous NIMorazole Versus RADiotherapy Alone in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Not Suitable for Synchronous Chemotherapy or Cetuximab)(NIMRAD) | completed | Phase 3 | 338 | The Christie NHS Foundation TrustOTHER | 1 | Oct 19, 2021 | clinicaltrials |
| NCT02551159 | Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck Cancer(KESTREL) | completed | Phase 3 | 823 | AstraZenecaINDUSTRY | 23 | Oct 13, 2021 | clinicaltrials |
| NCT01353625 | Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies. | completed | Phase 1 | 118 | CelgeneINDUSTRY | 4 | Oct 5, 2021 | clinicaltrials |
| NCT01816984 | PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer | completed | Phase 1 / Phase 2 | 12 | University of ChicagoOTHER | 1 | Oct 5, 2021 | clinicaltrials |
| NCT03212157 | GlucoCEST MRI in Oncology | completed | N/A | 15 | University College, LondonOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT05049408 | Verification of Saliva MMP-1 as a Diagnostic Marker of Oral Cavity Cancer | completed | — | 1,160 | S&T Biomed Co., Ltd.INDUSTRY | 1 | Sep 28, 2021 | clinicaltrials |
| NCT03367780 | Dose-Effect Relation of Salivary Gland Irradiation | completed | — | 32 | The Netherlands Cancer InstituteOTHER | 1 | Aug 19, 2021 | clinicaltrials |
| NCT03022409 | A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC). | completed | Phase 1 | 21 | AstraZenecaINDUSTRY | 3 | Aug 10, 2021 | clinicaltrials |
| NCT03349710 | Nivolumab or Nivolumab Plus Cisplatin, in Combination With Radiotherapy in Patients With Cisplatin-ineligible or Eligible Locally Advanced Squamous Cell Head and Neck Cancer | completed | Phase 3 | 74 | Bristol-Myers SquibbINDUSTRY | 10 | Aug 9, 2021 | clinicaltrials |
| NCT04260074 | Epigenetic Changes in Head and Neck Cancer | completed | — | 40 | Aalborg University HospitalOTHER | 1 | Jul 21, 2021 | clinicaltrials |
| NCT03421912 | Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitors (iEGFR)(CICAFIX) | completed | N/A | 102 | Centre Leon BerardOTHER | 1 | Jul 9, 2021 | clinicaltrials |
| NCT03182959 | Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer | completed | Early Phase 1 | 6 | University of ArizonaOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT02544880 | PDE5 Inhibition Via Tadalafil to Enhance Anti-Tumor Mucin 1 (MUC1) Vaccine Efficacy in Patients With HNSCC | completed | Phase 1 | 16 | Donald T. Weed, MD, FACSOTHER | 1 | Jun 15, 2021 | clinicaltrials |
| NCT01427478 | Evaluation of Afatinib in Maintenance Therapy in Squamous Cell Carcinoma of the Head and Neck(BIBW2992ORL) | completed | Phase 3 | 134 | Centre Leon BerardOTHER | 1 | Jun 1, 2021 | clinicaltrials |
| NCT02762513 | Expansion Trial for Axitinib In Head And Neck Cancer | completed | Phase 2 | 29 | University of Michigan Rogel Cancer CenterOTHER | 1 | May 5, 2021 | clinicaltrials |
| NCT02537223 | Phase I Study of BYL719 in Combination With Cisplatin and Radiotherapy in Patients With Squamous Cell Head and Neck Cancer | completed | Phase 1 | 9 | University Health Network, TorontoOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT03194373 | Phase II Trial Evaluating the Efficacy of Palbociclib in Combination With Carboplatin for the Treatment of Unresectable Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | completed | Phase 2 | 21 | University of Michigan Rogel Cancer CenterOTHER | 1 | Apr 12, 2021 | clinicaltrials |
| NCT00896181 | Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC) | completed | Phase 2 | 26 | Stanford UniversityOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT04098458 | Navigation for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC | completed | N/A | 18 | Medical University of South CarolinaOTHER | 1 | Mar 22, 2021 | clinicaltrials |
| NCT03144778 | Durvalumab With or Without Tremelimumab in Treating Participants With Stage II-IVA Oropharyngeal Squamous Cell Cancer | completed | Phase 1 | 39 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT00084682 | Depsipeptide in Unresectable Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck | completed | Phase 2 | 14 | National Cancer Institute (NCI)NIH | 1 | Mar 5, 2021 | clinicaltrials |
| NCT01663259 | Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients | completed | N/A | 43 | University of Michigan Rogel Cancer CenterOTHER | 1 | Jan 19, 2021 | clinicaltrials |
| NCT01414426 | Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions | completed | Phase 2 | 20 | University of ChicagoOTHER | 1 | Jan 14, 2021 | clinicaltrials |
| NCT02794675 | Intraoperative Placement of Cesium-131 Permanent Interstitial Brachytherapy in Head and Neck Cancer | completed | Early Phase 1 | 15 | Case Comprehensive Cancer CenterOTHER | 1 | Dec 23, 2020 | clinicaltrials |
| NCT01598077 | A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer | completed | Phase 1 | 54 | Novartis PharmaceuticalsINDUSTRY | 5 | Dec 19, 2020 | clinicaltrials |
| NCT00210470 | A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer | completed | Phase 2 | 27 | Brooklyn ImmunoTherapeutics, LLCINDUSTRY | 0 | Dec 11, 2020 | clinicaltrials |
| NCT01689194 | Efficacy Study of Genexol-PM and Cisplatin in Locally Advanced Head and Neck Cancer | completed | Phase 2 | 53 | Seoul National University HospitalOTHER | 1 | Dec 8, 2020 | clinicaltrials |
| NCT02025062 | Comprehensive Geriatric Assessment and Head and Neck Elderly Cancer Patients(EGéSOR) | completed | N/A | 499 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 23, 2020 | clinicaltrials |
| NCT03538028 | A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies | completed | Phase 1 | 22 | Incyte Biosciences International SàrlINDUSTRY | 1 | Oct 30, 2020 | clinicaltrials |
| NCT01386632 | Study of DCA (Dichloroacetate) in Combination With Cisplatin and Definitive Radiation in Head and Neck Carcinoma | completed | Phase 2 | 50 | Sanford HealthOTHER | 1 | Oct 27, 2020 | clinicaltrials |
| NCT00736944 | Trial of 2 Cycles of Induction Chemo With Abraxane, Cetuximab, Cisplatin, & 5-FU for Advanced Head and Neck Cancer | completed | Phase 2 | 30 | Washington University School of MedicineOTHER | 1 | Sep 9, 2020 | clinicaltrials |
| NCT04525066 | Phonosurgical Augmentation After Laser Resection of Early Glottic Carcinoma | completed | Phase 2 | 39 | Ayhman Al AfifOTHER | 0 | Aug 25, 2020 | clinicaltrials |
| NCT02124707 | Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN | completed | Phase 2 | 14 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Aug 12, 2020 | clinicaltrials |
| NCT01314755 | A Trial of Perioperative Immune Enhancing Feed in Patients Undergoing Surgery for Head and Neck Cancer(IMPACTHN) | completed | N/A | 76 | Terrence JonesOTHER_GOV | 1 | Aug 7, 2020 | clinicaltrials |
| NCT02279459 | Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas | completed | — | 23 | Ottawa Hospital Research InstituteOTHER | 1 | Aug 6, 2020 | clinicaltrials |
| NCT04361409 | Rituximab Plus Chemotherapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma | completed | Phase 1 | 10 | China Medical University HospitalOTHER | 1 | Apr 28, 2020 | clinicaltrials |
| NCT00609284 | Randomized Trial of Concomitant Chemotherapy in Patients With Locally Advanced HNSCC Treated by Radiotherapy-erbitux(2007-01) | completed | Phase 3 | 406 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Apr 15, 2020 | clinicaltrials |
| NCT03433027 | A Study of BB-401 in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | completed | Phase 2 | 16 | Benitec Biopharma, Inc.INDUSTRY | 2 | Apr 15, 2020 | clinicaltrials |
| NCT01344356 | Stereotactic Body Radiotherapy for Head and Neck Tumors | completed | Phase 4 | 19 | Mercy ResearchOTHER | 1 | Apr 10, 2020 | clinicaltrials |
| NCT00957853 | Preoperative Treatment With Cetuximab and/or IMC-A12 | completed | Phase 2 | 16 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 19, 2020 | clinicaltrials |
| NCT01044433 | Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck | completed | Phase 2 | 44 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Mar 19, 2020 | clinicaltrials |
| NCT01254617 | Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer(ADCC) | completed | Phase 1 | 24 | National Cancer Institute (NCI)NIH | 1 | Mar 13, 2020 | clinicaltrials |
| NCT01697800 | A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract | completed | Phase 2 | 40 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Feb 28, 2020 | clinicaltrials |
| NCT01469429 | Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer. | completed | Phase 1 / Phase 2 | 70 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT01504932 | Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors | completed | N/A | 42 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT02882308 | Preoperative Administration of Olaparib With Cisplatin or With Durvalumab or Alone or no Tratment in Patients Who Are Candidates for Surgery of Carcinoma of the Head and Neck.(OPHELIA) | completed | Phase 2 | 41 | Hellenic Cooperative Oncology GroupOTHER | 1 | Feb 7, 2020 | clinicaltrials |
| NCT01816841 | Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care | completed | N/A | 68 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jan 30, 2020 | clinicaltrials |
| NCT01998542 | Safety and Tolerability Study of AlloVax(TM) in Patients With Metastatic or Recurrent Cancer of the Head and Neck(HNC) | completed | Phase 2 | 12 | Mirror Biologics, Inc.INDUSTRY | 1 | Jan 23, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Nov 5, 2021source: clinicaltrials