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Clinical trials
341 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01738139 | Ipilimumab and Imatinib Mesylate in Advanced Cancer | completed | Phase 1 | 68 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 21, 2024 | clinicaltrials |
| NCT02734823 | Long Term Effects of Tyrosine Kinase Inhibitor Therapy on Ovarian Reserve and Fertility in Patients With Chronic Myeloid Leukemia or Gastrointestinal Stromal Tumor | withdrawn | — | 0 | University of Southern CaliforniaOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT04276415 | DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST) | terminated | Phase 1 | 34 | Daiichi SankyoINDUSTRY | 2 | Feb 15, 2024 | clinicaltrials |
| NCT04409223 | Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib | terminated | Phase 3 | 185 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Feb 9, 2024 | clinicaltrials |
| NCT01735955 | Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored Study | completed | Phase 4 | 57 | Novartis PharmaceuticalsINDUSTRY | 16 | Feb 8, 2024 | clinicaltrials |
| NCT04599660 | Study in Low Risk Gastrointestinal Stromal Tumor (GISTs)(RetroGIST) | completed | — | 700 | Italian Sarcoma GroupNETWORK | 1 | Feb 1, 2024 | clinicaltrials |
| NCT02260505 | Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)(ImadGist) | completed | Phase 3 | 136 | Centre Leon BerardOTHER | 1 | Jan 5, 2024 | clinicaltrials |
| NCT01541709 | Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI | unknown | Phase 2 | 23 | Asan Medical CenterOTHER | 1 | Jan 2, 2024 | clinicaltrials |
| NCT04927260 | French Long Term Registry With Longitudinal Follow up of PDGFRA D842V-GIST Patients(AVIATOR2020) | unknown | — | 25 | Centre Leon BerardOTHER | 1 | Dec 26, 2023 | clinicaltrials |
| NCT02571036 | A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies | completed | Phase 1 | 282 | Deciphera Pharmaceuticals, LLCINDUSTRY | 6 | Dec 13, 2023 | clinicaltrials |
| NCT02232620 | A Study of BBI503 in Adult Patients With Advanced Gastrointestinal Stromal Tumors | terminated | Phase 2 | 2 | Sumitomo Pharma America, Inc.INDUSTRY | 1 | Nov 14, 2023 | clinicaltrials |
| NCT04198337 | Endoscopic Full Thickness Resection for Gastric GIST(EFTR) | unknown | N/A | 30 | Chinese University of Hong KongOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT04006769 | Entacapone Combination With Imatinib for Treatment of GIST | completed | Early Phase 1 | 5 | Xiangya Hospital of Central South UniversityOTHER | 1 | Oct 18, 2023 | clinicaltrials |
| NCT02500797 | Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery | completed | Phase 2 | 164 | National Cancer Institute (NCI)NIH | 1 | Oct 17, 2023 | clinicaltrials |
| NCT05453292 | Endoscopic Ultrasound Radiofrequency Ablation for GISTs | unknown | N/A | 30 | Instituto Ecuatoriano de Enfermedades DigestivasOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT05474794 | Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions | unknown | N/A | 30 | Instituto Ecuatoriano de Enfermedades DigestivasOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT01376505 | Vaccine Therapy in Treating Patients With Metastatic Solid Tumors | completed | Phase 1 | 65 | Robert WesolowskiOTHER | 1 | Sep 15, 2023 | clinicaltrials |
| NCT05009927 | Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten) | recruiting | Phase 2 | 50 | Centre Leon BerardOTHER | 1 | Sep 1, 2023 | clinicaltrials |
| NCT05970900 | Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GIST(PIRKER) | not yet recruiting | Phase 3 | 23 | Fujian Medical University Union HospitalOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT00764595 | Imatinib Mesylate in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor(GISTs) | completed | Phase 2 | 5 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 1 | Jul 21, 2023 | clinicaltrials |
| NCT00769782 | Surgery in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor(GISTs) | completed | Phase 2 | 6 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 1 | Jul 21, 2023 | clinicaltrials |
| NCT05938309 | A Cohort Study on the Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal Tumors | recruiting | — | 194 | Fujian Medical UniversityOTHER | 1 | Jul 10, 2023 | clinicaltrials |
| NCT02365441 | A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST)(ALT GIST) | unknown | Phase 2 | 78 | Australasian Gastro-Intestinal Trials GroupNETWORK | 10 | Jul 7, 2023 | clinicaltrials |
| NCT05895942 | Exploring the Molecular Mechanism Based on KIT Mutation(EMMBKM) | unknown | — | 190 | Xijing HospitalOTHER | 1 | Jun 9, 2023 | clinicaltrials |
| NCT04254939 | A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor | completed | Phase 1 / Phase 2 | 65 | CStone PharmaceuticalsINDUSTRY | 1 | Apr 27, 2023 | clinicaltrials |
| NCT05800106 | A Bioequivalence Study of Sunitinib Malate Capsules. | completed | Phase 1 | 24 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Apr 10, 2023 | clinicaltrials |
| NCT00716820 | Special Investigation For Gist Of Sunitinib Malate (Regulatory Post Marketing Commitment Plan). | completed | — | 472 | PfizerINDUSTRY | 0 | Apr 6, 2023 | clinicaltrials |
| NCT04811833 | Gastrointestinal Anastomosis Using MonoPlus® Suture(GASTROMO) | withdrawn | — | 0 | Aesculap AGINDUSTRY | 1 | Apr 5, 2023 | clinicaltrials |
| NCT02638766 | Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST(REGISTRI) | completed | Phase 2 | 15 | Grupo Espanol de Investigacion en SarcomasOTHER | 3 | Mar 27, 2023 | clinicaltrials |
| NCT04138381 | Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST)(SeliGIST) | unknown | Phase 1 / Phase 2 | 30 | Grupo Espanol de Investigacion en SarcomasOTHER | 1 | Mar 27, 2023 | clinicaltrials |
| NCT03475953 | A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors(REGOMUNE) | unknown | Phase 1 / Phase 2 | 747 | Institut BergoniéOTHER | 1 | Mar 3, 2023 | clinicaltrials |
| NCT05751733 | Apatinib Mesylate Versus Standard Second-line TKI in the Treatment of Advanced GIST | recruiting | N/A | 258 | Xiangya Hospital of Central South UniversityOTHER | 1 | Mar 2, 2023 | clinicaltrials |
| NCT00812240 | Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST) | terminated | Phase 3 | 335 | AB ScienceINDUSTRY | 3 | Feb 1, 2023 | clinicaltrials |
| NCT04077372 | Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers | terminated | N/A | 12 | Stanford UniversityOTHER | 1 | Jan 27, 2023 | clinicaltrials |
| NCT04476082 | Nutrition in Gastrointestinal Tumors(NutriGIT) | completed | — | 66 | University Medicine GreifswaldOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT05697107 | Ripretinib in Chinese Patients With Advanced GIST: a Real World Study | unknown | — | 308 | Peking UniversityOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT02712112 | A Study of Intermittent Dosing Schedule of Imatinib in Patients With Tyrosine Kinase Inhibitor Refractory GISTs | completed | Phase 2 | 51 | Asan Medical CenterOTHER | 1 | Jan 4, 2023 | clinicaltrials |
| NCT03609424 | PDR001 Plus Imatinib for Metastatic or Unresectable GIST | completed | Phase 1 / Phase 2 | 39 | Asan Medical CenterOTHER | 1 | Jan 3, 2023 | clinicaltrials |
| NCT05665868 | Study on Integrated Nursing Strategy for Patients With Gastrointestinal Stromal Tumors After Targeted Therapy | unknown | N/A | 62 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Dec 27, 2022 | clinicaltrials |
| NCT05641233 | Preoperative Radiotherapy in Patients at High Risk of Postoperative Pancreatic Fistula After Pancreatoduodenectomy(FIBROPANC-1) | unknown | Phase 1 / Phase 2 | 33 | Erasmus Medical CenterOTHER | 1 | Dec 7, 2022 | clinicaltrials |
| NCT05565066 | A Real-world Comparison of FNB and FNA in IHC-required Lesions. | completed | — | 439 | Huazhong University of Science and TechnologyOTHER | 1 | Dec 1, 2022 | clinicaltrials |
| NCT03353753 | Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer Therapies(INVICTUS) | completed | Phase 3 | 129 | Deciphera Pharmaceuticals, LLCINDUSTRY | 13 | Nov 21, 2022 | clinicaltrials |
| NCT00623831 | A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen | completed | Phase 1 | 17 | Ludwig Institute for Cancer ResearchOTHER | 1 | Oct 25, 2022 | clinicaltrials |
| NCT03465722 | (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST | completed | Phase 3 | 476 | Blueprint Medicines CorporationINDUSTRY | 18 | Oct 6, 2022 | clinicaltrials |
| NCT05408897 | Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD | recruiting | — | 45 | Peking University People's HospitalOTHER | 1 | Sep 21, 2022 | clinicaltrials |
| NCT02880020 | Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery | completed | Phase 2 | 36 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 18, 2022 | clinicaltrials |
| NCT02071862 | Study of the Glutaminase Inhibitor CB-839 in Solid Tumors | completed | Phase 1 | 210 | Calithera Biosciences, IncINDUSTRY | 1 | Jul 20, 2022 | clinicaltrials |
| NCT02508532 | (NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors | completed | Phase 1 | 250 | Blueprint Medicines CorporationINDUSTRY | 10 | Jun 21, 2022 | clinicaltrials |
| NCT05400018 | Clinical Evaluation of Genetron D842V PCR Kit in GIST Patients | completed | — | 1,041 | Genetron HealthINDUSTRY | 1 | Jun 6, 2022 | clinicaltrials |
| NCT05354388 | Ripretinib Combined With Surgery in Advanced GIST That Have Failed Imatinib Therapy: A Multicenter,Observational Study | unknown | — | 30 | Sichuan Provincial People's HospitalOTHER | 1 | Apr 29, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Mar 21, 2024source: clinicaltrials