Cancer Family
Esophageal Neoplasm
CI-CAN-00000174Explore in graph →
Non-malignant555 active trials6 approved drugs12 evidence items
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Cancer Family
CI-CAN-00000174Explore in graph →
Clinical trials
2,208 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02037048 | FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma | unknown | Phase 2 | 63 | Case Comprehensive Cancer CenterOTHER | 1 | Jan 8, 2024 | clinicaltrials |
| NCT06190847 | Oral Microbiome is Associated With the Response to Chemoradiotherapy in Initial Inoperable Patients With Esophageal Squamous Cell Cancer | unknown | — | 97 | Anhui Provincial HospitalOTHER_GOV | 1 | Jan 5, 2024 |
| clinicaltrials |
| NCT05626569 | Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC | unknown | Phase 2 | 40 | Sun Yat-sen UniversityOTHER | 1 | Jan 3, 2024 | clinicaltrials |
| NCT06186609 | PD-1 Inhibitor Combined With Radiotherapy for Elderly ESCC | unknown | Phase 2 | 68 | Affiliated Hospital of Nantong UniversityOTHER | 1 | Jan 2, 2024 | clinicaltrials |
| NCT03587532 | Assessment of Graft Perfusion and Oxygenation for Improved Outcome in Esophageal Cancer Surgery(EDOBS) | unknown | N/A | 70 | University Hospital, GhentOTHER | 1 | Dec 28, 2023 | clinicaltrials |
| NCT06125262 | Trajectory Analysis of NLR and Its Association With Efficacy of Immunochemotherapy in ESCC. | unknown | — | 100 | Guangdong Provincial People's HospitalOTHER | 1 | Dec 28, 2023 | clinicaltrials |
| NCT06147180 | Comparison of Long-term Survival and Quality of Life After Minimally Invasive Esophagectomy Versus Open Esophagectomy | unknown | — | 1,474 | Qilu Hospital of Shandong UniversityOTHER | 1 | Nov 27, 2023 | clinicaltrials |
| NCT05512520 | Concurrent Chemoradiotherapy for Stage IVB Esophageal Squamous Cell Carcinoma(EC-CRT-003)(EC-CRT-003) | unknown | Phase 2 | 126 | Sun Yat-sen UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT05376423 | To Evaluate OBI-833/OBI-821 in Patients With Locally Advanced, Globo H-Positive Esophageal Cancer for Recurrence | unknown | Phase 2 | 60 | National Taiwan University HospitalOTHER | 1 | Nov 15, 2023 | clinicaltrials |
| NCT06103890 | Dynamic ctDNA Monitoring in Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma(ctDNA) | unknown | — | 100 | Hebei Medical University Fourth HospitalOTHER | 1 | Oct 27, 2023 | clinicaltrials |
| NCT06092944 | Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy | unknown | N/A | 96 | Luo FuchaoOTHER | 1 | Oct 23, 2023 | clinicaltrials |
| NCT06078657 | IBI110 Combined With Sintilimab in Second-line Advanced or Metastatic Esophageal Squamous Cell Carcinoma(ESCC) | unknown | Phase 2 | 46 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Oct 12, 2023 | clinicaltrials |
| NCT03081988 | Prediction Model of Response for CCRT in Esophageal Cancer | unknown | — | 140 | Kyungpook National University HospitalOTHER | 1 | Oct 4, 2023 | clinicaltrials |
| NCT06061263 | Risk Factors of Relapse in Esophageal Squamous Cell Cancers Who Achieve PCR to Neoadjuvant Chemoradiotherapy | unknown | — | 96 | Sun Yat-sen UniversityOTHER | 1 | Sep 29, 2023 | clinicaltrials |
| NCT03283527 | Organoid Based Response Prediction in Esophageal Cancer(RARESTEM/Org) | unknown | — | 100 | University Medical Center GroningenOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT06055166 | A Clinical Study of Chemoradiotherapy Sequential Fluzoparib in Pan-solid Tumors | unknown | Phase 2 | 120 | Chongqing University Cancer HospitalOTHER | 0 | Sep 26, 2023 | clinicaltrials |
| NCT06045715 | Follow-up Strategy for Esophageal Cancer Patients | unknown | — | 3,000 | Sun Yat-sen UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT05990231 | Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy | unknown | Phase 2 | 35 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Sep 11, 2023 | clinicaltrials |
| NCT06031155 | Swedish Esophageal and Cardia Cancer Study(SECC) | unknown | — | 616 | Karolinska InstitutetOTHER | 0 | Sep 11, 2023 | clinicaltrials |
| NCT06022978 | Submucosal Saline Injection Followed by Endoscopic Ultrasound(EUS-SSI) | unknown | N/A | 432 | Sun Yat-sen UniversityOTHER | 1 | Sep 5, 2023 | clinicaltrials |
| NCT06012318 | Dynamic Follow-up of Symptoms Based on Patient-reported Outcomes in Immunotherapy for Esophageal Cancer: a Prospective Multicentre Cohort Study (SPRING) | unknown | — | 220 | Guangdong Provincial People's HospitalOTHER | 1 | Aug 25, 2023 | clinicaltrials |
| NCT06009705 | Toripalimab Combined With Radiotherapy and S-1 for Older Patients With Esophageal Cancer(Best-EEC) | unknown | — | 56 | Hebei Medical University Fourth HospitalOTHER | 1 | Aug 24, 2023 | clinicaltrials |
| NCT06010212 | Fruquintinib as First Line Treatment in Patients With Recurrent Esophageal Squamous Cell Carcinoma | unknown | Phase 1 / Phase 2 | 36 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Aug 24, 2023 | clinicaltrials |
| NCT05996484 | Neoadjuvant Therapy of Anlotinib Combined With Toripalimab and Chemotherapy for Resectable Esophageal Carcinoma | unknown | Phase 2 | 25 | Nanfang Hospital, Southern Medical UniversityOTHER | 0 | Aug 21, 2023 | clinicaltrials |
| NCT05688020 | Tranexamic Acid During Upper GI Endoscopic Resection Procedures | unknown | Phase 4 | 200 | Assaf-Harofeh Medical CenterOTHER_GOV | 1 | Aug 9, 2023 | clinicaltrials |
| NCT03790553 | Comparing 61.2 Gy Radiotherapy Dose Versus 50.4 Gy Radiotherapy Dose for Locally Advanced Esophageal Carcinoma | unknown | Phase 3 | 646 | Fudan UniversityOTHER | 1 | Aug 3, 2023 | clinicaltrials |
| NCT05718284 | High Flow Nasal Cannula After Esophagectomy(OSSIGENA1V) | unknown | N/A | 320 | Cristian DeanaOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05760391 | A Study of IO Plus Radiotherapy in Patients With Advanced ESCC. | unknown | N/A | 100 | Fudan UniversityOTHER | 1 | Jul 25, 2023 | clinicaltrials |
| NCT05937477 | Developing Artificial Intelligence-based Algorism to Predict Side Effects and Symptoms From Chemotherapy | unknown | — | 500 | Sehhoon ParkOTHER | 1 | Jul 21, 2023 | clinicaltrials |
| NCT04566367 | Blue Laser Imaging (BLI) for Detection of Secondary Head and Neck Cancer | unknown | N/A | 140 | Georg DultzOTHER | 1 | Jul 13, 2023 | clinicaltrials |
| NCT05281003 | Pembrolizumab Plus Chemo in Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma (Eastern Cooperative Thoracic Oncology Projects 2004, ECTOP-2004)(HYPERION) | unknown | Phase 2 | 128 | Fudan UniversityOTHER | 1 | Jul 13, 2023 | clinicaltrials |
| NCT05927844 | XH-30002 Capsule Combined With Afatinib Tablets for the Treatment of Squamous Cell Carcinoma | unknown | Phase 1 | 20 | Fujian Cancer HospitalOTHER_GOV | 0 | Jul 3, 2023 | clinicaltrials |
| NCT05603065 | Tislelizumab With Chemotherapy or Radiation for Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma (TINES)(TINES) | unknown | Phase 4 | 32 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Jun 29, 2023 | clinicaltrials |
| NCT03427346 | Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection(BEEPER) | unknown | N/A | 407 | Universitätsklinikum Hamburg-EppendorfOTHER | 2 | Jun 28, 2023 | clinicaltrials |
| NCT05412628 | Investigating the Association Between Microbiota and Esophageal/Oropharyngeal Cancer | unknown | N/A | 60 | National Cheng-Kung University HospitalOTHER | 1 | Jun 23, 2023 | clinicaltrials |
| NCT05247346 | Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements(SENSITIVE) | unknown | N/A | 60 | University Medical Center GroningenOTHER | 1 | Jun 13, 2023 | clinicaltrials |
| NCT05900583 | Efficacy Evaluation and Recurrence Monitoring of Therapy for Esophageal Squamous Cell Carcinoma Based on ctDNA-MRD. | unknown | — | 50 | Guangdong Provincial People's HospitalOTHER | 1 | Jun 12, 2023 | clinicaltrials |
| NCT05896787 | Candonilimab (AK104) Plus Preoperative Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (ESCC) | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jun 9, 2023 | clinicaltrials |
| NCT03094884 | Pulsed Low Dose Rate Radiation With Concurrent Chemotherapy for Non-Small Cell Lung Cancer and Esophageal Cancer | unknown | Phase 1 | 40 | Fox Chase Cancer CenterOTHER | 1 | May 23, 2023 | clinicaltrials |
| NCT05866510 | Utidelone and Anlotinib in Advanced Recurrent Metastatic Esophageal Cancer | unknown | Phase 2 | 47 | Peking UniversityOTHER | 1 | May 19, 2023 | clinicaltrials |
| NCT05038813 | Anlotinib Combined With TQB2450 (PD-L1 Inhibitor) in the Treatment of Advanced Esophageal Squamous Cell Carcinoma(ESCC) | unknown | Phase 2 | 46 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | May 18, 2023 | clinicaltrials |
| NCT05856500 | A Study of Creatine Combined With Curcumin in the Intervention of Early Cachexia in Upper Gastrointestinal Tumors | unknown | N/A | 152 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 0 | May 18, 2023 | clinicaltrials |
| NCT05865132 | Palbociclib Combined With Afatinib for Advanced Squamous Carcinoma of Esophagus or Gastroesophageal Junction | unknown | Phase 2 | 30 | AIPING ZHOUOTHER | 1 | May 18, 2023 | clinicaltrials |
| NCT05801666 | Acupuncture Effect on Dumping Syndrome in Esophagus Cancer Patients With Feeding Jejunostomy | unknown | N/A | 60 | China Medical University, TaiwanOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05846971 | Clinical Utility of Methylation-based Prognostic Assay for Barrett's Esophagus | unknown | N/A | 100 | Capsulomics, Inc.INDUSTRY | 1 | May 6, 2023 | clinicaltrials |
| NCT05833971 | Cadonilimab in Combination With Chemotherapy for Locally Advaced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 43 | Guangzhou Institute of Respiratory DiseaseOTHER | 0 | Apr 27, 2023 | clinicaltrials |
| NCT05830240 | A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer | unknown | Early Phase 1 | 9 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | Apr 26, 2023 | clinicaltrials |
| NCT05831150 | Discovering Patterns in Experiences of Patients in Esophageal Cancer Clinical Research | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 0 | Apr 26, 2023 | clinicaltrials |
| NCT05828381 | Envafolimab Combined With Abraxane and Cisplatinas as Neoadjuvant Treatment for Resectable Esophageal Cancer | unknown | Phase 2 | 33 | Fujian Medical University Union HospitalOTHER | 0 | Apr 25, 2023 | clinicaltrials |
| NCT05818982 | To Evaluate the Efficacy and Safety of Afatinib for Advanced ALTRK-negative ESCC | unknown | Phase 2 | 72 | Peking UniversityOTHER | 1 | Apr 19, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Jan 8, 2024source: clinicaltrials