Cancer Family
Esophageal Neoplasm
CI-CAN-00000174Explore in graph →
Non-malignant555 active trials6 approved drugs12 evidence items
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Cancer Family
CI-CAN-00000174Explore in graph →
Clinical trials
2,208 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07416825 | Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19 | completed | N/A | 23 | Institute of Oncology LjubljanaOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT03993353 | Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer | completed | Phase 2 | 7 | University of California, San DiegoOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT05787522 | Clinical Validation of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk | completed | — | 500 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT06027515 | Esophageal Cancer Multimodal Prehabilitation Study | completed | N/A | 15 | Massachusetts General HospitalOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT00628368 | Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer | completed | N/A | 160 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT04217239 | A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy | completed | N/A | 272 | The Second Hospital of Shandong UniversityOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05142709 | Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC. | completed | — | 1,197 | Fudan UniversityOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT03008278 | Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery | completed | Phase 1 / Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | Feb 3, 2026 | clinicaltrials |
| NCT07363629 | Impact of Preserving Versus Ligating the Right Gastric Artery on Anastomotic Outcomes After McKeown Esophagectomy: A Randomized Controlled Trial | completed | N/A | 120 | The First Hospital of Hebei Medical UniversityOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT04505553 | Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer | completed | Phase 2 | 78 | University of WashingtonOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT05453760 | Lung Ultrasound in the Early Detection of Postoperative Pulmonary Complications After Esophagectomy(OESOLUS) | completed | — | 274 | University Hospital, LilleOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT04045496 | A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors | completed | Phase 1 | 40 | Jacobio Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Dec 29, 2025 | clinicaltrials |
| NCT01618643 | Aceto-whitening in the Assessment of Gastrointestinal Neoplasia | completed | — | 197 | Portsmouth Hospitals NHS TrustOTHER_GOV | 1 | Dec 24, 2025 | clinicaltrials |
| NCT03246516 | Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers(DELOGAST) | completed | N/A | 258 | University Hospital, LilleOTHER | 1 | Dec 23, 2025 | clinicaltrials |
| NCT05342636 | A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A) | completed | Phase 1 / Phase 2 | 90 | Merck Sharp & Dohme LLCINDUSTRY | 13 | Dec 17, 2025 | clinicaltrials |
| NCT06549816 | A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors | completed | Phase 1 | 6 | Seagen, a wholly owned subsidiary of PfizerINDUSTRY | 1 | Dec 15, 2025 | clinicaltrials |
| NCT05406024 | Feasibility Study CORPPS(FAISA-CORPPS) | completed | — | 30 | University Hospital, LilleOTHER | 1 | Dec 11, 2025 | clinicaltrials |
| NCT04974047 | Study of Tislelizumab in Participants With Resectable Esophageal Squamous Cell Carcinoma(RATIONALE-213) | completed | Phase 2 | 70 | BeiGeneINDUSTRY | 1 | Dec 1, 2025 | clinicaltrials |
| NCT05795595 | A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors | completed | Phase 1 / Phase 2 | 19 | CRISPR Therapeutics AGINDUSTRY | 1 | Nov 26, 2025 | clinicaltrials |
| NCT07155330 | High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients | completed | N/A | 80 | Zhejiang UniversityOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT07236320 | Neoadjuvant Immunochemotherapy vs Chemoradiotherapy in ESCC | completed | N/A | 200 | Yongtao HanOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT05383482 | Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1 | completed | Phase 1 / Phase 2 | 22 | Laekna LimitedINDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT06129487 | Evaluations of Alcohol Warning Labels | completed | N/A | 1,053 | University of ConnecticutOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT02372929 | Relationship Between Endoscopic Ultrasound Staging and Degree of Stricture in Esophageal Cancer(ESOCA) | completed | — | 100 | AdventHealthOTHER | 1 | Nov 12, 2025 | clinicaltrials |
| NCT01191697 | CAPOX, Bevacizumab and Trastuzumab for Patients With HER2-Positive Metastatic Esophagogastric Cancer | completed | Phase 2 | 37 | Dana-Farber Cancer InstituteOTHER | 1 | Nov 3, 2025 | clinicaltrials |
| NCT04408105 | Survey Study on Barrett's Esophagus Screening(SCREEN-BE) | completed | — | 725 | University of Colorado, DenverOTHER | 1 | Oct 22, 2025 | clinicaltrials |
| NCT03819088 | Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer | completed | N/A | 17 | Emory UniversityOTHER | 1 | Oct 9, 2025 | clinicaltrials |
| NCT04526886 | Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy | completed | N/A | 52 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Oct 6, 2025 | clinicaltrials |
| NCT05051475 | Endoscopic Radiofrequency Ablation Versus Hybrid Argon Plasma Coagulation in the Treatment of Barrett's Esophagus(RATE) | completed | N/A | 62 | Centre of Postgraduate Medical EducationOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT02558504 | Radiofrequency in the Treatment of Barrett's Oesophagus(HARMONI) | completed | Phase 4 | 87 | Hospices Civils de LyonOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT06192212 | PPIO-005 The Relationship Between Different Nutritional Pathways and Tumor Outcomes After Minimally Invasive Esophagectomy | completed | — | 577 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT07201571 | A Retrospective Cohort Study of Patients Who Underwent Curative-intent Esophagectomy for ESCC at a Tertiary Referral Center in South Korea | completed | — | 3,131 | Samsung Medical CenterOTHER | 0 | Oct 1, 2025 | clinicaltrials |
| NCT06333665 | PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy | completed | — | 605 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Sep 30, 2025 | clinicaltrials |
| NCT07182266 | Perioperative Outcomes and Survival of Inflatable Video-Assisted Mediastinoscopic Transhiatal Esophagectomy for Selected Esophageal Cancer | completed | — | 1,661 | Shanghai Zhongshan HospitalOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT07181850 | Predicting Pathological Complete Response in Esophageal Squamous Cell Carcinoma Using a Multimodal Model Integrating Clinical, Radiomics, and Deep Learning Features(pCR-ESCC) | completed | — | 363 | Nanjing Medical UniversityOTHER | 1 | Sep 18, 2025 | clinicaltrials |
| NCT00924027 | A Study of Patients Receiving High-Dose Rate Brachytherapy | completed | Phase 2 | 43 | National Cancer Institute (NCI)NIH | 1 | Sep 5, 2025 | clinicaltrials |
| NCT02415101 | Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Esophageal Cancer(NeoResII) | completed | N/A | 202 | Karolinska University HospitalOTHER | 1 | Sep 3, 2025 | clinicaltrials |
| NCT04772989 | A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies(ARC-12) | completed | Phase 1 | 94 | Arcus Biosciences, Inc.INDUSTRY | 3 | Aug 28, 2025 | clinicaltrials |
| NCT05880082 | PPIO-004 Clinical Application of Efficacy Prediction Model Based on Epigenomics Sequencing Technology in Neoadjuvant Immunotherapy for Esophageal Cancer(PPIO-004-EC001) | completed | Phase 2 | 118 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT03708328 | A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors | completed | Phase 1 | 134 | Hoffmann-La RocheINDUSTRY | 6 | Aug 20, 2025 | clinicaltrials |
| NCT04825834 | DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)(DELFI-L101) | completed | — | 2,992 | Delfi Diagnostics Inc.INDUSTRY | 2 | Aug 8, 2025 | clinicaltrials |
| NCT02872116 | Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer(CheckMate649) | completed | Phase 3 | 2,031 | Bristol-Myers SquibbINDUSTRY | 29 | Aug 7, 2025 | clinicaltrials |
| NCT06275165 | The Effects of Acupressure on Improving Postoperative Gastrointestinal Symptom Distress in Esophageal Cancer Patients | completed | N/A | 48 | CHEN, CHIA-CHENOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT02013154 | A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab(P102) | completed | Phase 1 | 151 | Leap Therapeutics, Inc.INDUSTRY | 1 | Aug 3, 2025 | clinicaltrials |
| NCT02534233 | Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium(ColdPlay2) | completed | N/A | 58 | Johns Hopkins UniversityOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT03783442 | A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 3 | 649 | BeiGeneINDUSTRY | 16 | Jul 29, 2025 | clinicaltrials |
| NCT03797625 | Endostar Combined With IP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas | completed | Phase 2 | 52 | Fudan UniversityOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT04242199 | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors | completed | Phase 1 | 182 | Incyte CorporationINDUSTRY | 5 | Jul 14, 2025 | clinicaltrials |
| NCT05494359 | The Diagnostic Value of Nitrogen Element (N) in Esophagus Cancer | completed | — | 120 | Hepatopancreatobiliary Surgery Institute of Gansu ProvinceOTHER | 1 | Jul 14, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Feb 18, 2026source: clinicaltrials