Cancer Family
Digestive System Neoplasm
CI-CAN-00000012Explore in graph →
Non-malignant4,733 active trials43 approved drugs557 evidence items
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Cancer Family
CI-CAN-00000012Explore in graph →
Clinical trials
22,059 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05511688 | National Cohort of Colorectal Cancers With Microsatellite Instability | active not recruiting | — | 637 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT05585320 | A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 209 | Immuneering CorporationINDUSTRY | 1 | Sep 2, 2025 |
| NCT05669482 | Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer(RAMP205) | active not recruiting | Phase 1 / Phase 2 | 40 | Verastem, Inc.INDUSTRY | 1 | Sep 2, 2025 | clinicaltrials |
| NCT07147452 | Sentinel Lymph Node Detection in Gastric Cancer Using a Dual Tracer (Superparamagnetic Iron Oxide and Methylene Blue): A Prospective Study With Histological and OSNA Validation(SLN_GC_SPIO) | active not recruiting | — | 44 | Hospital del SAS de JerezOTHER | 1 | Aug 29, 2025 | clinicaltrials |
| NCT05629065 | Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC)((PATH-SIC)) | active not recruiting | N/A | 800 | Dana-Farber Cancer InstituteOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT03907852 | Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer | active not recruiting | Phase 1 / Phase 2 | 57 | TCR2 TherapeuticsINDUSTRY | 2 | Aug 27, 2025 | clinicaltrials |
| NCT01088789 | Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer | active not recruiting | Phase 2 | 71 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT06728358 | The Future Management of Patients With Neoplasms of the Gastro-intestinal Tract(SOCRATE) | active not recruiting | N/A | 300 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT07142421 | A Study of Trifluridine/Tipiracil Combined With Anlotinib as Second-line Treatment for Recurrent and Metastatic Esophageal Squamous Cell Carcinoma | active not recruiting | Phase 2 | 35 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT07137000 | The Effect of Art Therapy in Patients Undergoing Colorectal Cancer | active not recruiting | N/A | 96 | Saglik Bilimleri UniversitesiOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT04166604 | LONsurf and G-CSF Use: Being On A Right Dose-intensity to Optimize Treatment Efficacy(LONGBOARD) | active not recruiting | Phase 2 | 176 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT03170960 | Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors | active not recruiting | Phase 1 | 914 | ExelixisINDUSTRY | 9 | Aug 17, 2025 | clinicaltrials |
| NCT03283540 | Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence | active not recruiting | — | 39 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT05613621 | Dissection of the Molecular and Immunological Interaction in Patients With HCC of Viral and Non-viral Etiologies(T4222) | active not recruiting | — | 579 | National Health Research Institutes, TaiwanOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT05822752 | Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)(LIVIGNO-1) | active not recruiting | Phase 2 | 130 | AbbVieINDUSTRY | 7 | Aug 14, 2025 | clinicaltrials |
| NCT06087718 | Feasibility of the Maastro Applicator in Rectal Cancer | active not recruiting | N/A | 10 | Maastricht Radiation OncologyOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT05029869 | Monitoring Minimal Residual Disease in Gastric Cancer by Liquid Biopsy Study Description | active not recruiting | — | 100 | University Medical Center Ho Chi Minh City (UMC)OTHER | 1 | Aug 13, 2025 | clinicaltrials |
| NCT05057013 | A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours | active not recruiting | Phase 1 / Phase 2 | 81 | Cancer Research UKOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT07113340 | Carina™ Surgical Platform for Minimal Radical Gastrectomy | active not recruiting | N/A | 20 | The Affiliated Hospital of Qingdao UniversityOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT05002127 | A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06) | active not recruiting | Phase 2 / Phase 3 | 127 | ALX Oncology Inc.INDUSTRY | 12 | Aug 7, 2025 | clinicaltrials |
| NCT07106463 | Microbiota: Its Role in Chronic Inflammation, IDB and Risk of Colorectal Cancer. Evaluation of a Predictive Prognostic Model With Therapeutic Implications | active not recruiting | — | 100 | University of MessinaOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT07104877 | A Study of SYS6010 in Combination With SYH2051 in Patients With Advanced Colorectal Cancer and Other Gastrointestinal Tumors | active not recruiting | N/A | 25 | Fujian Cancer HospitalOTHER_GOV | 1 | Aug 5, 2025 | clinicaltrials |
| NCT03493048 | Cetuximab Plus FOLFOXIRI vs Cetuximab Plus FOLFOX For CRCLM | active not recruiting | Phase 2 | 146 | Sun Yat-sen UniversityOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT03326791 | Aspirin in Colorectal Cancer Liver Metastases(ASAC) | active not recruiting | Phase 2 / Phase 3 | 466 | Oslo University HospitalOTHER | 3 | Jul 31, 2025 | clinicaltrials |
| NCT03651154 | Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic Resections(PRICE2) | active not recruiting | N/A | 440 | Ottawa Hospital Research InstituteOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT04025840 | Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery | active not recruiting | Phase 4 | 260 | Peking University First HospitalOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT05444491 | Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer | active not recruiting | — | 800 | Singlera Genomics Inc.INDUSTRY | 1 | Jul 31, 2025 | clinicaltrials |
| NCT06866574 | A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males | active not recruiting | Phase 3 | 9,300 | Xiamen UniversityOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT04852653 | A Prospective Feasibility Study Evaluating Extracellular Vesicles Obtained by Liquid Biopsy for Neoadjuvant Treatment Response Assessment in Rectal Cancer(RECC-EV) | active not recruiting | — | 58 | University Hospital, BordeauxOTHER | 1 | Jul 30, 2025 | clinicaltrials |
| NCT06105021 | Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor | active not recruiting | Phase 1 / Phase 2 | 100 | Affini-T Therapeutics, Inc.INDUSTRY | 1 | Jul 30, 2025 | clinicaltrials |
| NCT07022886 | INCIDENCE, PREVALENCE AND OVERALL RISK OF ESOPHAGEAL CANCER IN ACHALASIA: A PROPENSITY-MATCHED POPULATION-BASED STUDY FROM A LARGE MULTICENTER DATABASE(RECAP) | active not recruiting | — | 47,000 | IRCCS San RaffaeleOTHER | 1 | Jul 30, 2025 | clinicaltrials |
| NCT04186234 | SBRT for Liver Cancer Before Liver Transplantation | active not recruiting | N/A | 71 | The University of Hong KongOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT03161535 | Effectiveness of a Rehabilitation Program in Improving Quality of Life in Patients With Esophageal Cancer | active not recruiting | N/A | 85 | Taipei Veterans General Hospital, TaiwanOTHER_GOV | 1 | Jul 28, 2025 | clinicaltrials |
| NCT03421288 | Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness(DANTE) | active not recruiting | Phase 2 | 677 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 2 | Jul 25, 2025 | clinicaltrials |
| NCT03806309 | OSE2101+FOLFIRI, or FOLFIRI Maintenance After FOLFIRINOX-based Induction Therapy in Advanced or Metastatic PDAC(TEDOPAM) | active not recruiting | Phase 2 | 106 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT06398743 | First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer(MRD) | active not recruiting | — | 416 | Exact Sciences CorporationINDUSTRY | 5 | Jul 24, 2025 | clinicaltrials |
| NCT03597204 | Effectiveness of Fecal Immunnochemical Test and Colonoscopy Screening in Hong Kong | active not recruiting | N/A | 15,000 | Chinese University of Hong KongOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT03704480 | Durvalumab + Tremelimumab ± Paclitaxel in Advanced BTC After Platinum Chemotherapy.(IMMUNO-BIL) | active not recruiting | Phase 2 | 106 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT05604560 | A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer | active not recruiting | Phase 2 | 25 | Lei ZhengOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT07080879 | The Advantages and Disadvantages of Linear Anastomat and Tubular Anastomat in Radical Gastrectomy of Distal Gastric Cancer | active not recruiting | N/A | 250 | Xiangya Hospital of Central South UniversityOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT06020885 | Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study. | active not recruiting | Phase 1 | 18 | Sun Yat-sen UniversityOTHER | 1 | Jul 21, 2025 | clinicaltrials |
| NCT03694938 | Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients | active not recruiting | N/A | 143 | Poitiers University HospitalOTHER | 1 | Jul 20, 2025 | clinicaltrials |
| NCT07074535 | CT and Endoscopic Biopsy Image-Based Deep Learning for Predicting Left Recurrent Laryngeal Nerve Lymph Node Metastasis in Esophageal Cancer | active not recruiting | — | 500 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Jul 20, 2025 | clinicaltrials |
| NCT03828227 | QoL in mCRC Elderly Patients Receiving First-line Therapy Based on Simplified Geriatric Parameters.(COLAGE) | active not recruiting | Phase 3 | 49 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jul 18, 2025 | clinicaltrials |
| NCT03348150 | Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination.(PERISCOPEII) | active not recruiting | Phase 3 | 102 | The Netherlands Cancer InstituteOTHER | 1 | Jul 17, 2025 | clinicaltrials |
| NCT06199973 | Injection of SHR-A1811 Versus Physician Choiced Treatment in Patients With Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-fu, and Irinotecan | active not recruiting | Phase 3 | 130 | Suzhou Suncadia Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Jul 17, 2025 | clinicaltrials |
| NCT06248528 | Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy. | active not recruiting | N/A | 1,076 | Chen XiaopingOTHER | 1 | Jul 16, 2025 | clinicaltrials |
| NCT06427252 | The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM | active not recruiting | Phase 2 | 50 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jul 16, 2025 | clinicaltrials |
| NCT07063550 | Microplastics in Paraneoplastic and Intratumoral for Colorectal Cancer | active not recruiting | — | 100 | Dong PengOTHER | 1 | Jul 14, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Sep 2, 2025source: clinicaltrials