Clinical trial · Observational
CT and Endoscopic Biopsy Image-Based Deep Learning for Predicting Left Recurrent Laryngeal Nerve Lymph Node Metastasis in Esophageal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to develop a predictive model for left recurrent laryngeal nerve (RLN) lymph node metastasis using deep learning algorithms. The model will be developed using clinical data from previous esophageal cancer surgeries, including preoperative CT imaging, and histopathological images from gastroscopic biopsies. The model will also be validated through prospective clinical trials to guide the intraoperative lymph node dissection, thereby reducing postoperative risks of RLN injury.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Deep Learning | — | UNRESOLVED | — |
| Esophageal Squamous Cell Cancer (SCC) | Esophageal Squamous Cell Carcinoma | ALIAS | 0.85 |
| Postoperative Complication | — | UNRESOLVED | — |
| Recurrent Laryngeal Nerve Palsy | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Left RLN lymph node （+）
- description
- Postoperative pathological results confirmed the metastasis of left recurrent laryngeal nerve lymph nodes.
- label
- Left RLN lymph node （-）
- description
- Postoperative pathological results confirmed the negative of left recurrent laryngeal nerve lymph nodes.
Primary outcomes (1)
- measure
- AUROC (Area Under the Receiver Operating Characteristic Curve)
- timeFrame
- From enrollment to the end of treatment at 4 weeks
- description
- The discriminant ability of the comprehensive evaluation model at different thresholds (positive vs. negative)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Preoperative gastroscopic biopsy confirmed esophageal squamous cell carcinoma； * The patient underwent esophagectomy with lymph nodes dissection along the left recurrent laryngeal nerve. Exclusion Criteria: * The patient's medical records are incomplete； * The patient refused to participate in the trial.
References
Publications (0)
Data not yet available