Cancer Family
Digestive System Intraepithelial Neoplasia
CI-CAN-00000163Explore in graph →
Non-malignant10 active trials
- NCIt
- C8962
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Cancer Family
CI-CAN-00000163Explore in graph →
Clinical trials
59 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03554356 | Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)(NO FEAR-BE) | active not recruiting | N/A | 70 | University of North Carolina, Chapel HillOTHER | 1 | Sep 14, 2026 | clinicaltrials |
| NCT05074264 | Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico(CAMPO-101) | active not recruiting | N/A | 1,586 | University of California, San FranciscoOTHER |
| 2 |
| Aug 24, 2026 |
| clinicaltrials |
| NCT06233331 | Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV | not yet recruiting | Phase 1 | 9 | Emory UniversityOTHER | 1 | Aug 18, 2026 | clinicaltrials |
| NCT06157671 | The LINFU® U.S. Registry for the Detection of Asymptomatic Pancreatic Ductal Adenocarcinoma | enrolling by invitation | — | 1,000 | Adenocyte, LLCINDUSTRY | 1 | Aug 6, 2026 | clinicaltrials |
| NCT02698293 | PDT Plus Vitamin D3 for Anal Dysplasia | withdrawn | Phase 1 | 0 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT05028725 | Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma | recruiting | N/A | 289 | University of California, San FranciscoOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07709052 | Predictive Biomarkers for Early Diagnosis of Pancreatic Ductal Adenocarcinoma (PDAC)(B-PDAC) | not yet recruiting | — | 180 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisOTHER | 0 | Jul 16, 2026 | clinicaltrials |
| NCT03603808 | VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions | completed | Phase 2 | 44 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 8, 2026 | clinicaltrials |
| NCT06342440 | Early Detection of Advanced Adenomas and Colorectal Cancer(AACRC) | recruiting | — | 2,000 | City of Hope Medical CenterOTHER | 5 | Jul 7, 2026 | clinicaltrials |
| NCT05334004 | Lopinavir/Ritonavir in PLWH With High-Grade AIN | recruiting | Phase 1 | 21 | University of Wisconsin, MadisonOTHER | 1 | May 15, 2026 | clinicaltrials |
| NCT06971276 | Assessing the Utility of Plasma ctHPVDNA for Anal Cancer Screening(SCAN-LITE) | completed | — | 104 | Massachusetts Eye and Ear InfirmaryOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT04312633 | Clinical Utility of WATS3D: A 5-Year Prospective Study | recruiting | — | 90,000 | CDx DiagnosticsINDUSTRY | 1 | Mar 20, 2026 | clinicaltrials |
| NCT07117045 | Artificial Intelligence-powered Low-Dose Computed Tomography for Screening of Pancreatic Cancer(AI-LDCT-PC) | recruiting | — | 400,000 | Changhai HospitalOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT02534233 | Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium(ColdPlay2) | completed | N/A | 58 | Johns Hopkins UniversityOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06866574 | A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males | active not recruiting | Phase 3 | 9,300 | Xiamen UniversityOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT02059499 | Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions | completed | Phase 3 | 91 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 23, 2025 | clinicaltrials |
| NCT05555862 | Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL(anal HSIL HIV-) | active not recruiting | Phase 2 | 17 | Frantz Viral Therapeutics, LLCINDUSTRY | 1 | May 18, 2025 | clinicaltrials |
| NCT03061435 | Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.(Vulvar-AIN) | recruiting | N/A | 110 | Dr. Danielle VicusOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT05266898 | Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV(AGO-Gard) | recruiting | Phase 4 | 250 | Louisiana State University Health Sciences Center in New OrleansOTHER | 1 | Apr 18, 2025 | clinicaltrials |
| NCT04276935 | Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions | completed | — | 20 | AIDS Malignancy ConsortiumNETWORK | 1 | Mar 7, 2025 | clinicaltrials |
| NCT06276803 | The LINFU® U.S. Registry for the in the General Population Without Risk Factors | not yet recruiting | — | 500 | Adenocyte, LLCINDUSTRY | 0 | Jul 31, 2024 | clinicaltrials |
| NCT04055142 | Clinical Trial for Evaluating the Efficacy and Safety of Electrocoagulation vs Topic Sinecatechins vs Topic Cidofovir Within the Treatment to High-grade Anal Intraepithelial Neoplasia in HIV Homosexual Males(TreatAIN) | completed | Phase 3 | 108 | Hospital Universitari Vall d'Hebron Research InstituteOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT06381583 | A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma(EMERALD) | completed | — | 658 | City of Hope Medical CenterOTHER | 1 | May 10, 2024 | clinicaltrials |
| NCT06389448 | Comparison of pCLE and EB in Gastric Lesion Diagnosis | recruiting | N/A | 366 | Huazhong University of Science and TechnologyOTHER | 1 | May 7, 2024 | clinicaltrials |
| NCT06327568 | Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens | recruiting | — | 200 | European Institute of OncologyOTHER | 1 | Mar 26, 2024 | clinicaltrials |
| NCT03051516 | HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions | terminated | Phase 4 | 188 | Fred Hutchinson Cancer CenterOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT02146508 | Endoscopic Prevention of Esophageal Cancer at Tenwek Hospital(EXPECT) | suspended | N/A | 75 | Tenwek HospitalOTHER | 1 | Dec 11, 2023 | clinicaltrials |
| NCT05542030 | CAD EYE Detection of Remaining Lesions After EMR | unknown | N/A | 60 | Instituto Ecuatoriano de Enfermedades DigestivasOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT03713229 | Seville Cohort of People Living With HIV at Risk for Anal Cancer(SeVIHanal) | enrolling by invitation | — | 3,000 | Hospitales Universitarios Virgen del RocíoOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT02238938 | Piecemeal Versus En Bloc Resection of Large Rectal Adenomas(PERLA) | terminated | N/A | 110 | Universitätsklinikum Hamburg-EppendorfOTHER | 2 | Jun 29, 2023 | clinicaltrials |
| NCT05858021 | COrSIcA: Disease Measurement | unknown | — | 30 | David FinchOTHER | 0 | May 15, 2023 | clinicaltrials |
| NCT05835947 | Anal Cancer Risk In Women | unknown | — | 200 | Imperial College LondonOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT05835960 | Anal Intraepithelial Neoplasia and Anal Squamous Cell Carcinoma | unknown | — | 20 | Imperial College LondonOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT02988934 | The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry | terminated | — | 3,173 | CDx DiagnosticsINDUSTRY | 1 | Feb 8, 2023 | clinicaltrials |
| NCT01802203 | trūFreeze® Spray Cryotherapy Patient Registry | completed | — | 275 | US Endoscopy Group Inc.INDUSTRY | 1 | Jul 25, 2022 | clinicaltrials |
| NCT02503111 | The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men(HPV-SAVE) | terminated | N/A | 71 | University Health Network, TorontoOTHER | 1 | Jun 13, 2022 | clinicaltrials |
| NCT03947775 | HPV-SAVE_Merck_Sub-Study for Preventing Recurrence of HSIL | unknown | Phase 2 | 228 | University Health Network, TorontoOTHER | 1 | Jun 13, 2022 | clinicaltrials |
| NCT03008980 | WATS3D for the Detection of Esophageal Dysplasia | completed | — | 160 | CDx DiagnosticsINDUSTRY | 1 | Nov 4, 2021 | clinicaltrials |
| NCT03100045 | Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)(ART-AIN) | completed | Phase 1 | 18 | Johns Hopkins UniversityOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT04109573 | Function Following Laser for Anal Intraepithelial Neoplasia (FLAN)(FLAN) | unknown | N/A | 20 | Homerton University Hospital NHS Foundation TrustOTHER | 1 | Aug 31, 2021 | clinicaltrials |
| NCT04843397 | Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study(PROSPERO) | unknown | — | 1,000 | University of CambridgeOTHER | 0 | Apr 15, 2021 | clinicaltrials |
| NCT02087384 | HPV (Human Papilloma Virus) Vaccination After Treatment of Anal Intraepithelial Neoplasia (AIN)(VACCAIN-P) | completed | Phase 4 | 126 | Prof. Jan PrinsOTHER | 1 | Mar 5, 2021 | clinicaltrials |
| NCT01913223 | Endoscopic Sub-mucosal Dissection With the Nestis® Jet Injector System With a Bi-functional Catheter: First Prospective Trial(NESTIS) | completed | N/A | 17 | Hospices Civils de LyonOTHER | 1 | May 28, 2019 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT01923116 | Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia(VACCAIN-T) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Mar 15, 2018 | clinicaltrials |
| NCT03302858 | A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand | unknown | Phase 2 | 70 | Stephen E. GoldstoneOTHER | 1 | Oct 5, 2017 | clinicaltrials |
| NCT01637298 | Biomarkers to Detect Anal Intraepithelial Neoplasia in Thai Men Who Have Sex With Men | completed | — | 450 | Thai Red Cross AIDS Research CentreOTHER | 0 | May 9, 2017 | clinicaltrials |
| NCT02189161 | A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia | completed | N/A | 10 | Medtronic - MITGINDUSTRY | 1 | Jul 14, 2016 | clinicaltrials |
Data updated 16 days agoSource updated Sep 14, 2026source: clinicaltrials