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CancerIndexthe global index of cancer

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Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

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CancerIndex

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Diffuse Glioma — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
Neuroepithelial Neoplasm
Glioma
Diffuse Glioma

Subtype

Diffuse Glioma

CI-CAN-00002519Explore in graph →

Non-malignant787 active trials5 approved drugs147 evidence items

NCIt: C129325
OncoTree: DIFG

Overview
Statistics
Survival
Genomics24
Variants & evidence147
Drugs34
Trials2804
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (105)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 76–100 of 105 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation.
· J Neuropathol Exp Neurol · 2021 · PMID 34363682 · validated civic_curation pubmed
Supratentorial ependymoma with YAP1:FAM118B fusion: A case report.
· Neuropathology · 2021 · PMID 33480048 · validated civic_curation pubmed
Entrectinib demonstrates prolonged efficacy in an adult case of radiation-refractory NTRK fusion glioblastoma.
· Neurooncol Adv · 2022 · PMID 35673607 · validated civic_curation pubmed
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
· Science · 2013 · PMID 23558169 · validated civic_curation pubmed
ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma.
· Sci Transl Med · 2016 · PMID 26936505 · validated civic_curation pubmed
A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.
· Cell Rep · 2018 · PMID 29949764 · validated civic_curation pubmed
Contribution of ATM and ATR to the resistance of glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide.
· Mol Cancer Ther · 2013 · PMID 23960094 · validated civic_curation pubmed

Showing 76–100 of 105 publications

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Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.

· Cancer Res · 2010 · PMID 20354191 · validated civic_curation pubmed

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.

· PLoS Med · 2006 · PMID 17177598 · validated civic_curation pubmed

Rare but Recurrent ROS1 Fusions Resulting From Chromosome 6q22 Microdeletions are Targetable Oncogenes in Glioma.

· Clin Cancer Res · 2018 · PMID 30171048 · validated civic_curation pubmed

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.

· Oncotarget · 2017 · PMID 28002790 · validated civic_curation pubmed

Tyrosine receptor kinase B is a drug target in astrocytomas.

· Neuro Oncol · 2017 · PMID 27402815 · validated civic_curation pubmed

Preclinical Test of Dacomitinib, an Irreversible EGFR Inhibitor, Confirms Its Effectiveness for Glioblastoma.

· Mol Cancer Ther · 2015 · PMID 25939761 · validated civic_curation pubmed

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma.

· Proc Natl Acad Sci U S A · 2012 · PMID 22203985 · validated civic_curation pubmed

Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.

· Oncotarget · 2017 · PMID 29156677 · validated civic_curation pubmed

Barthel & Johnson et al. Nature 2019

· 2019 · PMID 31748746 · validated cbioportal_study pubmed

Ankush et al. Clin Cancer Res 2024

· 2024 · PMID 37910594 · validated cbioportal_study pubmed

Zhao et al. Nat Med 2019

· 2019 · PMID 30742119 · validated cbioportal_study pubmed

Wang et al. Cell 2021

· 2021 · PMID 33577785 · validated cbioportal_study pubmed

Cloughesy et al. Nat Med. 2019

· 2019 · PMID 30742122 · validated cbioportal_study pubmed

Vaubel et al. Clin Cancer Res 2020

· 2020 · PMID 31852831 · validated cbioportal_study pubmed

TCGA, Nature 2008

· 2008 · PMID 18772890 · validated cbioportal_study pubmed

TCGA, Cell 2013

· 2013 · PMID 24120142 · validated cbioportal_study pubmed

Miller et al. Nature 2019

· 2019 · PMID 30675060 · validated cbioportal_study pubmed

Jonsson et al. Clin Cancer Res 2019

· 2019 · PMID 31263031 · validated cbioportal_study pubmed