Subtype
Colorectal Carcinoma
CI-CAN-00005005CRCExplore in graph →
344 active trials5 approved drugs22 evidence items
- NCIt
- C2955
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Subtype
CI-CAN-00005005CRCExplore in graph →
Clinical trials
1,010 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (127)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03981614 | Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer | completed | Phase 2 | 102 | Academic and Community Cancer Research UnitedOTHER | 1 | Aug 22, 2024 | clinicaltrials |
| NCT05130060 | A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer | completed | Phase 1 | 15 | Mayo ClinicOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT03752398 | A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)(DUET-3) | completed | Phase 1 | 198 | Xencor, Inc.INDUSTRY | 1 | Jul 5, 2024 | clinicaltrials |
| NCT03993327 | An Imaging Agent (I-124 M5A) in Detecting CEA-Positive Liver Metastases in Patients With Colorectal Cancer | completed | Phase 1 | 4 | City of Hope Medical CenterOTHER | 1 | Jun 28, 2024 | clinicaltrials |
| NCT02408406 | PatientCareAnywhere Internet-Based Software in Improving Communication and Education in Patients With Cancer and Their Healthcare Providers | completed | N/A | 140 | City of Hope Medical CenterOTHER | 1 | Jun 27, 2024 | clinicaltrials |
| NCT05458986 | A Video Intervention to Decrease Patient Fear of Colonoscopy After a Positive Fecal Immunochemical Test | completed | N/A | 66 | Fred Hutchinson Cancer CenterOTHER | 1 | May 30, 2024 | clinicaltrials |
| NCT04752267 | 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases | completed | Early Phase 1 | 10 | University of Southern CaliforniaOTHER | 1 | May 24, 2024 | clinicaltrials |
| NCT01851369 | TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas | completed | Phase 1 / Phase 2 | 93 | National Cancer Institute (NCI)NIH | 1 | May 8, 2024 | clinicaltrials |
| NCT02132858 | Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation | completed | — | 43 | Fox Chase Cancer CenterOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT04205955 | Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors | completed | Phase 2 | 95 | SWOG Cancer Research NetworkNETWORK | 2 | May 1, 2024 | clinicaltrials |
| NCT01447732 | Phase 1 Study of CEP-37250/KHK2804 in Subjects With Advanced Solid Tumors | completed | Phase 1 | 71 | Kyowa Kirin Co., Ltd.INDUSTRY | 0 | Apr 29, 2024 | clinicaltrials |
| NCT04898842 | Feasibility Study of a 4 Stage Bowel Obstruction Cancer Diet(BOUNCED) | completed | N/A | 30 | Royal Surrey County Hospital NHS Foundation TrustOTHER | 1 | Apr 10, 2024 | clinicaltrials |
| NCT03317119 | Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery | completed | Phase 1 | 26 | City of Hope Medical CenterOTHER | 1 | Apr 8, 2024 | clinicaltrials |
| NCT03373188 | VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer | completed | Phase 1 | 10 | Emory UniversityOTHER | 1 | Mar 20, 2024 | clinicaltrials |
| NCT06314737 | Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer | completed | — | 3,515 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Mar 18, 2024 | clinicaltrials |
| NCT06316401 | Endoscopic Submucosal Dissection of Large Recto-sigmoid Lesions Under Spinal Anesthesia | completed | — | 20 | Azienda USL ModenaOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT06271980 | Early-Onset Colorectal Cancer Recurrence(ENCORE) | completed | — | 177 | City of Hope Medical CenterOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT03665285 | A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors | completed | Phase 1 / Phase 2 | 109 | NextCure, Inc.INDUSTRY | 1 | Mar 8, 2024 | clinicaltrials |
| NCT05083338 | Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy | completed | — | 24 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 13, 2024 | clinicaltrials |
| NCT03843957 | Effectiveness and Implementation of mPATH-CRC | completed | N/A | 77,145 | Wake Forest University Health SciencesOTHER | 1 | Jan 31, 2024 | clinicaltrials |
| NCT06216405 | Performance of Artificial Intelligence in Colonoscopy for Right Colon Polyp Detection(AIRCOP) | completed | N/A | 2,000 | Groupe Hospitalier Diaconesses Croix Saint-SimonOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT05810714 | Audio and Video Brochures for Increasing Colorectal Cancer Screening Among Adults Living in Appalachia | completed | N/A | 94 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Dec 5, 2023 | clinicaltrials |
| NCT02599324 | Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors | completed | Phase 1 / Phase 2 | 263 | Pharmacyclics LLC.INDUSTRY | 4 | Nov 18, 2023 | clinicaltrials |
| NCT05022511 | Three Birds With One Stone | completed | N/A | 27,099 | University of AarhusOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT02729298 | First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors | completed | Phase 1 | 177 | Sumitomo Pharma America, Inc.INDUSTRY | 1 | Nov 14, 2023 | clinicaltrials |
| NCT03206073 | A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer | completed | Phase 1 / Phase 2 | 34 | National Cancer Institute (NCI)NIH | 1 | Oct 24, 2023 | clinicaltrials |
| NCT06083974 | Metastatic Left Colon and Rectal Cancer Treatment With Anti_EGFR Targeted Therapy(EGFR) | completed | — | 100 | Assiut UniversityOTHER | 0 | Oct 16, 2023 | clinicaltrials |
| NCT02551237 | Neoadjuvant Treatment for Advanced Rectal Carcinoma(NACRE) | completed | Phase 3 | 103 | UNICANCEROTHER | 1 | Oct 13, 2023 | clinicaltrials |
| NCT06031376 | Fruquintinib With PD-1 Inhibitors Versus TAS-102 With Bevacizumab in Late-Line mCRC | completed | — | 106 | Hunan Cancer HospitalOTHER | 1 | Sep 11, 2023 | clinicaltrials |
| NCT01830621 | BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinoma | completed | Phase 3 | 282 | NCIC Clinical Trials GroupNETWORK | 3 | Aug 28, 2023 | clinicaltrials |
| NCT04371198 | Patient-Derived Organoids for Rectal Cancer | completed | N/A | 20 | Duke UniversityOTHER | 1 | Aug 28, 2023 | clinicaltrials |
| NCT02232152 | CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery | completed | Phase 1 | 19 | Wake Forest University Health SciencesOTHER | 1 | Aug 7, 2023 | clinicaltrials |
| NCT05976282 | Addressing Colorectal Cancer in South Florida Firefighters | completed | N/A | 646 | University of MiamiOTHER | 1 | Aug 4, 2023 | clinicaltrials |
| NCT02460198 | Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164) | completed | Phase 2 | 124 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jul 27, 2023 | clinicaltrials |
| NCT03717519 | Elevated Platelet Count as Prognostic Factor in Colorectal Cancer With Synchronous Liver Metastases(PLTCRC) | completed | — | 196 | Azienda Ospedaliera Universitaria Integrata VeronaOTHER | 1 | Jul 20, 2023 | clinicaltrials |
| NCT05942768 | Anti-PD-1 Antibody Plus Regorafenib in Refractory Microsatellite Stable Metastatic Colorectal Cancer | completed | — | 103 | Hunan Cancer HospitalOTHER | 1 | Jul 12, 2023 | clinicaltrials |
| NCT05933408 | TREM-1 - a New Marker of Serious Infectious Complications in Colorectal Surgery? | completed | — | 64 | Jagiellonian UniversityOTHER | 1 | Jul 7, 2023 | clinicaltrials |
| NCT04440943 | A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies | completed | Phase 1 | 27 | Celldex TherapeuticsINDUSTRY | 1 | Jun 18, 2023 | clinicaltrials |
| NCT04902144 | Clinical Outcomes for Offering Genetic Testing in a Tiered Approach | completed | N/A | 6 | Fred Hutchinson Cancer CenterOTHER | 1 | Jun 9, 2023 | clinicaltrials |
| NCT00179348 | Yoga-Based Rehabilitation Program in Reducing Physical and Emotional Side Effects in Patients With Cancer | completed | N/A | 399 | Albert Einstein College of MedicineOTHER | 1 | May 31, 2023 | clinicaltrials |
| NCT02740985 | A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies | completed | Phase 1 | 313 | AstraZenecaINDUSTRY | 1 | May 26, 2023 | clinicaltrials |
| NCT00593060 | Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer | completed | Phase 1 | 35 | Jeffrey W. Clark, MDOTHER | 1 | May 24, 2023 | clinicaltrials |
| NCT05871567 | Predictive Value of DNA Mismatch Repair System in Colorectal Cancers(DNAMMR) | completed | — | 403 | University of Campania Luigi VanvitelliOTHER | 0 | May 24, 2023 | clinicaltrials |
| NCT05872334 | The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery | completed | N/A | 120 | Samsung Medical CenterOTHER | 1 | May 24, 2023 | clinicaltrials |
| NCT05869097 | Trifluridine/Tipiracil Plus Bevacizumab Versus Trifluridine/Tipiracil Monotherapy in Refractory Metastatic Colorectal Cancer | completed | — | 90 | Hunan Cancer HospitalOTHER | 1 | May 22, 2023 | clinicaltrials |
| NCT01420874 | Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer) | completed | Phase 1 | 15 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT03849469 | A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors(DUET-4) | completed | Phase 1 | 78 | Xencor, Inc.INDUSTRY | 1 | Mar 30, 2023 | clinicaltrials |
| NCT03385980 | Donation of Post Mortem Tumor Tissues(DONUM) | completed | — | 20 | Niguarda HospitalOTHER | 1 | Mar 22, 2023 | clinicaltrials |
| NCT04080414 | Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence | completed | N/A | 7 | University of UtahOTHER | 1 | Mar 22, 2023 | clinicaltrials |
| NCT03801915 | Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers | completed | Phase 2 | 10 | National Cancer Institute (NCI)NIH | 1 | Mar 21, 2023 | clinicaltrials |
Data updated 22 days agoSource updated Aug 22, 2024source: clinicaltrials