Precursor Condition
Cervical Intraepithelial Neoplasia
CI-CAN-00000664CINExplore in graph →
Precursor45 active trials
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Precursor Condition
CI-CAN-00000664CINExplore in graph →
Clinical trials
316 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03284866 | HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV(COVENANT) | completed | Phase 3 | 536 | AIDS Malignancy ConsortiumNETWORK | 5 | Jan 28, 2026 | clinicaltrials |
| NCT04537156 | Efficacy, Immunogenicity and Safety Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli) | active not recruiting | Phase 3 | 9,327 | Xiamen UniversityOTHER | 1 | Nov 21, 2025 |
| clinicaltrials |
| NCT03721978 | REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) | completed | Phase 3 | 203 | Inovio PharmaceuticalsINDUSTRY | 10 | Oct 17, 2024 | clinicaltrials |
| NCT04895020 | Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years | unknown | Phase 3 | 1,200 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Apr 17, 2024 | clinicaltrials |
| NCT03185013 | REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)(REVEAL 1) | completed | Phase 3 | 201 | Inovio PharmaceuticalsINDUSTRY | 19 | Jul 27, 2023 | clinicaltrials |
| NCT02733068 | A Phase III Study of Human Papillomavirus (HPV)-16/18 Vaccine. | completed | Phase 3 | 12,000 | Shanghai Zerun Biotechnology Co.,LtdINDUSTRY | 0 | Dec 19, 2022 | clinicaltrials |
| NCT05580341 | Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9 | unknown | Phase 3 | 1,200 | Shanghai Zerun Biotechnology Co.,LtdINDUSTRY | 1 | Oct 28, 2022 | clinicaltrials |
| NCT04484415 | Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL)(APRICITY) | unknown | Phase 3 | 402 | Asieris MediTech (Hong Kong) Co., Ltd.INDUSTRY | 1 | Aug 12, 2022 | clinicaltrials |
| NCT02330471 | Forced Versus Spray Coagulation in Women Undergoing LLETZ-conization for Cervical Dysplasia: a Randomized Trial(CONE-1) | completed | Phase 3 | 160 | Ruhr University of BochumOTHER | 1 | Jul 8, 2022 | clinicaltrials |
| NCT00000758 | A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women | completed | Phase 3 | 158 | National Institute of Allergy and Infectious Diseases (NIAID)NIH | 2 | Nov 4, 2021 | clinicaltrials |
| NCT00001073 | Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors | completed | Phase 3 | 150 | National Institute of Allergy and Infectious Diseases (NIAID)NIH | 3 | Nov 4, 2021 | clinicaltrials |
| NCT04646954 | DNA Methylation Testing for the Screening of Uterine Cervical Lesion | unknown | Phase 3 | 12,000 | Lei LiOTHER | 1 | Nov 30, 2020 | clinicaltrials |
| NCT03848039 | Impact on Disease Relapse of HPV Vaccination in Women Treated With LEEP for Cervical Intraepithelial Neoplasia. HOPE9(HOPE9) | not yet recruiting | Phase 3 | 1,220 | Alessandro GhelardiOTHER | 0 | Nov 5, 2020 | clinicaltrials |
| NCT01735006 | Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine | completed | Phase 3 | 7,372 | Xiamen UniversityOTHER | 1 | Feb 24, 2020 | clinicaltrials |
| NCT01131312 | Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) | completed | Phase 3 | 5,060 | National Cancer Institute (NCI)NIH | 1 | Nov 20, 2018 | clinicaltrials |
| NCT02346227 | Impact of AV2 Antiviral Drug on the Treatment of HPV-associated Lesions of the Uterine Cervix(KINVAV) | completed | Phase 3 | 327 | Jean-Pierre Van geertruydenOTHER | 1 | Oct 12, 2018 | clinicaltrials |
| NCT02562508 | A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | completed | Phase 3 | 979 | Jun ZhangOTHER | 1 | Aug 16, 2018 | clinicaltrials |
| NCT02329171 | Imiquimod Treatment of CIN Lesions(TOPIC) | terminated | Phase 3 | 9 | Maastricht University Medical CenterOTHER | 1 | Aug 15, 2018 | clinicaltrials |
| NCT02669459 | Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol(TopIC-2) | unknown | Phase 3 | 433 | Erasmus Medical CenterOTHER | 1 | Feb 6, 2018 | clinicaltrials |
| NCT03366493 | The Study of Folate Receptor-Mediated Staining Solution (FRD™) In Cervical Lesion Detection | unknown | Phase 3 | 200 | GY Highland Biotech LLCINDUSTRY | 1 | Dec 8, 2017 | clinicaltrials |
| NCT02130323 | Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix | completed | Phase 2 / Phase 3 | 22 | United States Naval Medical Center, San DiegoFED | 1 | Jun 27, 2017 | clinicaltrials |
| NCT00337818 | Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women | completed | Phase 3 | 770 | GlaxoSmithKlineINDUSTRY | 1 | May 30, 2017 | clinicaltrials |
| NCT00212381 | Oral Diindolylmethane (DIM) for the Treatment of Cervical Dysplasia | completed | Phase 3 | 62 | New York Presbyterian HospitalOTHER | 1 | Mar 29, 2017 | clinicaltrials |
| NCT01283763 | Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia(ITIC2) | terminated | Phase 3 | 95 | Medical University of ViennaOTHER | 1 | Nov 1, 2016 | clinicaltrials |
| NCT01929993 | A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins | completed | Phase 3 | 164 | Oswaldo Cruz FoundationOTHER | 1 | Jul 23, 2015 | clinicaltrials |
| NCT00995020 | Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion | completed | Phase 3 | 103 | Oswaldo Cruz FoundationOTHER | 1 | Jul 10, 2015 | clinicaltrials |
| NCT00264732 | A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine Cervix | completed | Phase 2 / Phase 3 | 251 | Eisai Inc.INDUSTRY | 1 | May 29, 2013 | clinicaltrials |
| NCT01505920 | Lidocaine Spray Compared With Submucosal Injection During LEEP: a Randomized Controlled Trial | completed | Phase 3 | 101 | Chiang Mai UniversityOTHER | 1 | Jan 15, 2013 | clinicaltrials |
| NCT00316706 | Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine | completed | Phase 3 | 1,245 | GlaxoSmithKlineINDUSTRY | 5 | Sep 18, 2012 | clinicaltrials |
| NCT01095198 | Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) | unknown | Phase 2 / Phase 3 | 1,440 | McMaster UniversityOTHER | 1 | Jul 21, 2011 | clinicaltrials |
| NCT01014026 | Self-sampling and Human Papillomavirus (HPV)-Testing for Unscreened Women in Cervical Cancer Prevention(APACHE-1) | completed | Phase 3 | 734 | University Hospital, ToursOTHER | 1 | May 13, 2011 | clinicaltrials |
| NCT00941252 | ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial(ITIC) | completed | Phase 2 / Phase 3 | 60 | Medical University of ViennaOTHER | 1 | Jan 24, 2011 | clinicaltrials |
| NCT00156026 | Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1 | completed | Phase 3 | 415 | Ontario Clinical Oncology Group (OCOG)OTHER | 2 | Jan 29, 2009 | clinicaltrials |
| NCT00237562 | Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit | completed | Phase 3 | — | University of California, IrvineOTHER | 1 | May 5, 2006 | clinicaltrials |
Data updated 22 days agoSource updated Jan 28, 2026source: clinicaltrials