Precursor Condition
Cervical Intraepithelial Neoplasia
CI-CAN-00000664CINExplore in graph →
Precursor45 active trials
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Precursor Condition
CI-CAN-00000664CINExplore in graph →
Clinical trials
316 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07545746 | Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treatment Outcomes in Women With HIV in Kenya(ASCEND) | not yet recruiting | Phase 2 | 140 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Aug 27, 2026 | clinicaltrials |
| NCT07669363 | Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL)(Aurora) | not yet recruiting | Phase 2 | 230 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
| 1 |
| Jul 9, 2026 |
| clinicaltrials |
| NCT07572396 | Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities | recruiting | Phase 2 | 45 | Amplexd Therapeutics, Inc.INDUSTRY | 1 | May 14, 2026 | clinicaltrials |
| NCT07454915 | PVX4 for the Treatment of Human Papilloma Virus (HPV)16+ Cervical Dysplasia | recruiting | Phase 2 | 138 | PapiVax Biotech, Inc.OTHER | 2 | May 6, 2026 | clinicaltrials |
| NCT04712851 | Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia | recruiting | Phase 2 | 25 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT02858310 | E7 TCR T Cells for Human Papillomavirus-Associated Cancers | completed | Phase 1 / Phase 2 | 224 | National Cancer Institute (NCI)NIH | 1 | Mar 9, 2026 | clinicaltrials |
| NCT05502367 | A Study of ABI-2280 Vaginal Insert (Previously Referred to as ABI-2280 Vaginal Tablet) in Participants With Cervical Intraepithelial Neoplasia | terminated | Phase 1 / Phase 2 | 44 | Antiva BiosciencesINDUSTRY | 3 | Feb 19, 2026 | clinicaltrials |
| NCT04098744 | Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)(ART-CIN_IIB) | recruiting | Phase 2 | 78 | Frantz Viral Therapeutics, LLCINDUSTRY | 1 | Oct 2, 2025 | clinicaltrials |
| NCT07095478 | Safety and Efficacy of Oral Artesunate for Pre-cervical Cancer(NeoART-CIN) | not yet recruiting | Phase 2 | 28 | Metanoic Health Ltd.INDUSTRY | 1 | Jul 31, 2025 | clinicaltrials |
| NCT03267680 | IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3 | terminated | Phase 2 | 10 | University of Southern CaliforniaOTHER | 1 | Apr 13, 2025 | clinicaltrials |
| NCT05496231 | A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age | completed | Phase 1 / Phase 2 | 1,080 | GlaxoSmithKlineINDUSTRY | 8 | Feb 3, 2025 | clinicaltrials |
| NCT06525870 | Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial(Trichlosil) | unknown | Phase 2 | 44 | Department of Medical Services Ministry of Public Health of ThailandOTHER_GOV | 1 | Nov 14, 2024 | clinicaltrials |
| NCT02864147 | Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) | completed | Phase 2 | 134 | Yale UniversityOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06273553 | A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3 | not yet recruiting | Phase 1 / Phase 2 | 39 | RinuaGene Biotechnology Co., Ltd.INDUSTRY | 0 | Feb 22, 2024 | clinicaltrials |
| NCT02481414 | A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions | completed | Phase 2 | 81 | University of ArkansasOTHER | 1 | Dec 18, 2023 | clinicaltrials |
| NCT06015854 | Vvax001 Cancer Vaccine in Premalignant Cervical Lesions - Phase II(Vvax) | unknown | Phase 2 | 18 | University Medical Center GroningenOTHER | 1 | Aug 29, 2023 | clinicaltrials |
| NCT02740777 | Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females | completed | Phase 2 | 900 | Shanghai Zerun Biotechnology Co.,LtdINDUSTRY | 1 | Apr 13, 2023 | clinicaltrials |
| NCT02529930 | An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) | completed | Phase 1 / Phase 2 | 34 | Nykode Therapeutics ASAINDUSTRY | 1 | Jul 13, 2022 | clinicaltrials |
| NCT04650711 | Immunohistochemical Staining of p16 for the Screening of Cervical Cancer | unknown | Phase 2 | 250 | Lei LiOTHER | 1 | Dec 3, 2020 | clinicaltrials |
| NCT01925378 | A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia | withdrawn | Phase 2 | 0 | The University of Texas Health Science Center, HoustonOTHER | 1 | Nov 12, 2020 | clinicaltrials |
| NCT03274206 | A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3) | unknown | Phase 2 | 126 | BioLeaders CorporationINDUSTRY | 1 | Feb 7, 2020 | clinicaltrials |
| NCT02631863 | Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1) | completed | Phase 2 | 60 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jul 8, 2019 | clinicaltrials |
| NCT02304770 | Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia | completed | Phase 2 | 73 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jun 12, 2019 | clinicaltrials |
| NCT03745846 | A Efficacy and Safety Study of Composite Gel Containing Black Raspberry Extract in Removing HPV From Patients With Cervical Intraepithelial Neoplasia(CIN) After Cervical Conization | unknown | Phase 2 | 78 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Nov 19, 2018 | clinicaltrials |
| NCT01304524 | A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3(HPV-003) | completed | Phase 2 | 167 | Inovio PharmaceuticalsINDUSTRY | 9 | Sep 7, 2018 | clinicaltrials |
| NCT03469531 | Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer | unknown | Phase 2 | 100 | Zhujiang HospitalOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT03143491 | Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN) | withdrawn | Phase 2 | 0 | DFB Soria, LLCINDUSTRY | 0 | Oct 18, 2017 | clinicaltrials |
| NCT03293628 | Comparing Two Techniques of Haemostasis After Cervical Conization | completed | Phase 2 | 100 | Barretos Cancer HospitalOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT00081263 | Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia | completed | Phase 2 | 130 | Gynecologic Oncology GroupNETWORK | 1 | Sep 15, 2017 | clinicaltrials |
| NCT02139267 | Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia | completed | Phase 2 | 72 | Genexine, Inc.INDUSTRY | 1 | Jul 12, 2017 | clinicaltrials |
| NCT02596243 | Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E) | unknown | Phase 2 | 134 | Genexine, Inc.INDUSTRY | 3 | Jul 12, 2017 | clinicaltrials |
| NCT02130323 | Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix | completed | Phase 2 / Phase 3 | 22 | United States Naval Medical Center, San DiegoFED | 1 | Jun 27, 2017 | clinicaltrials |
| NCT01022346 | A Study of RO5217790 in Participants With High Grade Cervical Intraepithelial Neoplasia (CIN) Associated With High Risk Human Papillomavirus (HR-HPV) Infection | completed | Phase 2 | 206 | Hoffmann-La RocheINDUSTRY | 6 | Aug 15, 2016 | clinicaltrials |
| NCT01116245 | An Assessment of an Attenuated Live Listeria Vaccine in CIN 2+(ADXS11-001) | terminated | Phase 2 | 81 | Advaxis, Inc.INDUSTRY | 1 | Jul 27, 2016 | clinicaltrials |
| NCT01256424 | Dose-finding Study of Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) to Treat Cervical Neoplasia | completed | Phase 2 | 262 | PhotocureINDUSTRY | 2 | May 16, 2016 | clinicaltrials |
| NCT02195089 | Efficacy and Safety Study of BLS_ILB_E710c for the Fertile Women With Cervical Intraepithelial Neoplasia(CIN3) | completed | Phase 1 / Phase 2 | 19 | BioLeaders CorporationINDUSTRY | 1 | Apr 19, 2016 | clinicaltrials |
| NCT00154089 | A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia | completed | Phase 1 / Phase 2 | 8 | Erimos PharmaceuticalsINDUSTRY | 1 | Feb 23, 2016 | clinicaltrials |
| NCT01826045 | Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia(PGA) | completed | Phase 2 | 200 | BioLeaders CorporationINDUSTRY | 1 | Jan 29, 2016 | clinicaltrials |
| NCT01356823 | Dose-Ranging Study of Recombinant Human Papillomavirus Virus 16/18 Bivalent Vaccine | completed | Phase 2 | 1,600 | Xiamen UniversityOTHER | 1 | Jan 5, 2016 | clinicaltrials |
| NCT01405768 | Buffered Lidocaine for Loop Electrosurgical Excision Procedures (LEEPs) | completed | Phase 2 | 56 | Washington University School of MedicineOTHER | 1 | Jul 28, 2014 | clinicaltrials |
| NCT02184975 | Cold Knife Conization With and Without Lateral Hemostatic Sutures | completed | Phase 2 | 100 | Barretos Cancer HospitalOTHER | 1 | Jul 9, 2014 | clinicaltrials |
| NCT00264732 | A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine Cervix | completed | Phase 2 / Phase 3 | 251 | Eisai Inc.INDUSTRY | 1 | May 29, 2013 | clinicaltrials |
| NCT00708942 | Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) of Cervical Intraepithelial Neoplasia (CIN) Grade 1 | terminated | Phase 2 | 83 | PhotocureINDUSTRY | 3 | Apr 24, 2013 | clinicaltrials |
| NCT01303328 | Safety and Efficacy Study of Antiviral Local Application to Treat High Grade Cervical Intraepithelial Lesions (CIN2/3)(Colvir-PhaseII) | completed | Phase 2 | 200 | Mithra PharmaceuticalsINDUSTRY | 1 | Feb 18, 2013 | clinicaltrials |
| NCT00247169 | Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II | completed | Phase 2 | 40 | Medical University of ViennaOTHER | 1 | Mar 9, 2012 | clinicaltrials |
| NCT01095198 | Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) | unknown | Phase 2 / Phase 3 | 1,440 | McMaster UniversityOTHER | 1 | Jul 21, 2011 | clinicaltrials |
| NCT00941252 | ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial(ITIC) | completed | Phase 2 / Phase 3 | 60 | Medical University of ViennaOTHER | 1 | Jan 24, 2011 | clinicaltrials |
| NCT00369018 | A Dose-finding Study of MAL and HAL Photodynamic Therapy of Cervical Premalignant Lesions. | completed | Phase 1 / Phase 2 | 96 | PhotocureINDUSTRY | 2 | Nov 30, 2010 | clinicaltrials |
| NCT00285207 | Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix | completed | Phase 2 | 147 | Tigris PharmaceuticalsINDUSTRY | 1 | Oct 11, 2010 | clinicaltrials |
| NCT00190983 | A Trial for Patients With Advanced/Recurrent Cervical Cancer | completed | Phase 2 | 29 | Eli Lilly and CompanyINDUSTRY | 1 | Nov 20, 2009 | clinicaltrials |
Data updated 22 days agoSource updated Aug 27, 2026source: clinicaltrials