Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
Loading cancer entity…
Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07533942 | A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma | recruiting | Phase 2 | 30 | Jazz PharmaceuticalsINDUSTRY | 1 | Jul 30, 2026 | clinicaltrials |
| NCT07735819 | Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a Glioma | not yet recruiting | Phase 2 | 61 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT02191488 | ALA-induced PpIX Fluorescence During Brain Tumor Resection | active not recruiting | Phase 1 | 540 | David W. RobertsOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT02691923 | Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker | active not recruiting | Phase 2 | 30 | David W. RobertsOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT05023551 | Study of DSP-0390 in Patients With Recurrent High-Grade Glioma | active not recruiting | Early Phase 1 | 39 | Sumitomo Pharma America, Inc.INDUSTRY | 2 | Jul 29, 2026 | clinicaltrials |
| NCT05045950 | Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique | recruiting | Phase 2 | 53 | Medical College of WisconsinOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT05284643 | Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma | recruiting | N/A | 96 | University of MiamiOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07271966 | B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy(BALANCE) | recruiting | N/A | 50 | Duke UniversityOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT02208362 | Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma | active not recruiting | Phase 1 | 65 | City of Hope Medical CenterOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT03180502 | Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma | active not recruiting | Phase 2 | 120 | NRG OncologyOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT04743661 | 131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma | active not recruiting | Phase 2 | 62 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07731555 | Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological Analyses | recruiting | N/A | 100 | Patrick MorrisOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07732140 | Listen Aphasia Pilot Study(LISTEN) | not yet recruiting | N/A | 80 | Dana-Farber Cancer InstituteOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07732413 | Trial of NLG802 Indoximod Prodrug Plus Temozolomide for Patients With Progressive Pediatric Brain Cancer | not yet recruiting | Phase 1 | 30 | Lumos PharmaINDUSTRY | 1 | Jul 28, 2026 | clinicaltrials |
| NCT05503797 | A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations | recruiting | Phase 2 | 254 | Fore BiotherapeuticsINDUSTRY | 12 | Jul 27, 2026 | clinicaltrials |
| NCT07725640 | Feasibility Assessment of a Medical Device for Tumour Cell Retention and Radiotherapy Sensitization in Patients With Suspected High-grade Glioma(CT-GlioHook) | not yet recruiting | N/A | 15 | Batea OncologyINDUSTRY | 1 | Jul 27, 2026 | clinicaltrials |
| NCT03155620 | Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) | active not recruiting | Phase 2 | 1,377 | National Cancer Institute (NCI)NIH | 4 | Jul 24, 2026 | clinicaltrials |
| NCT03922555 | ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas | recruiting | Phase 1 | 18 | Massachusetts General HospitalOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT05406700 | Niraparib In Recurrent IDH 1/2 Gliomas | active not recruiting | Early Phase 1 | 16 | Massachusetts General HospitalOTHER | 1 | Jul 24, 2026 | clinicaltrials |
| NCT06266949 | Perimetry Based on Eye-movements in Patients With (Supra)Sellar Tumors | not yet recruiting | — | 30 | University Medical Center GroningenOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT06942104 | Imaging of Solid Tumors Using 18F-TRX | recruiting | Phase 1 | 56 | Rahul AggarwalOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07606287 | Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital | not yet recruiting | N/A | 4,000 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07703605 | AI-Assisted MRI Molecular Subtyping in Pediatric Brain Tumors | not yet recruiting | — | 1,400 | Huashan HospitalOTHER | 0 | Jul 23, 2026 | clinicaltrials |
| NCT04427384 | Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) | recruiting | — | 600 | GT Medical Technologies, Inc.INDUSTRY | 1 | Jul 22, 2026 | clinicaltrials |
| NCT04521686 | Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations | active not recruiting | Phase 1 | 200 | Eli Lilly and CompanyINDUSTRY | 9 | Jul 22, 2026 | clinicaltrials |
| NCT05188508 | Pembrolizumab, Olaparib, and Temozolomide for People With Glioma | recruiting | Phase 2 | 57 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT05879250 | WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma | recruiting | Phase 2 | 39 | Northwestern UniversityOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT06973096 | CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy | active not recruiting | Phase 1 | 9 | University of PennsylvaniaOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT02288962 | Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas | active not recruiting | Phase 3 | 60 | St. Olavs HospitalOTHER | 2 | Jul 21, 2026 | clinicaltrials |
| NCT02886585 | Pembrolizumab In Central Nervous System Metastases | active not recruiting | Phase 2 | 101 | Massachusetts General HospitalOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT04992013 | Niraparib in Tumors Metastatic to the CNS | active not recruiting | Phase 2 | 20 | Massachusetts General HospitalOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT05416567 | Embolization for Meningioma(e-men) | recruiting | N/A | 30 | St. Olavs HospitalOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT06672575 | A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma | recruiting | Phase 1 / Phase 2 | 45 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT06910306 | Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma | recruiting | N/A | 10 | Alpha Tau Medical LTD.INDUSTRY | 1 | Jul 21, 2026 | clinicaltrials |
| NCT06969352 | A Multicentre, Retrospective-prospective Real-world Study: to Evaluate the Effectiveness and Safety of Vorasidenib in Patients With Isocitrate Dehydrogenase IDH1/2 Mutant Grade 2 Astrocytoma or Oligodendroglioma (VICTORIA Study)(VICTORIA) | active not recruiting | N/A | 62 | Servier (Tianjin) Pharmaceutical Co. LTD.INDUSTRY | 1 | Jul 21, 2026 | clinicaltrials |
| NCT06981156 | Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO) | recruiting | — | 252 | University of Wisconsin, MadisonOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT07717827 | Connectome-guided Onco-functional Resection With Tractography-Extended Neuronavigation in Brain Tumor Surgery(CORTEx) | recruiting | — | 400 | ARNAS Civico Di Cristina Benfratelli HospitalOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT02359565 | Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma | active not recruiting | Phase 1 | 71 | National Cancer Institute (NCI)NIH | 2 | Jul 20, 2026 | clinicaltrials |
| NCT04479696 | Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors | recruiting | N/A | 117 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT04900792 | A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma(XACT-Fe-GBM-01) | active not recruiting | Phase 1 | 16 | Bryan AllenOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT05278208 | Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors | recruiting | Phase 1 / Phase 2 | 65 | Nationwide Children's HospitalOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT06177964 | Lerapolturev (PVSRIPO) in GBM | recruiting | Phase 2 | 92 | Darell BignerOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT07713745 | Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2)(PRIME-NF2) | not yet recruiting | Phase 2 | 200 | Beijing Tiantan HospitalOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT07715097 | Survivin-Targeted Dendritic Cell (DC) Cell Injection for Newly Diagnosed Glioblastoma | not yet recruiting | Phase 2 | 30 | Beijing Tricision Biotherapeutics IncINDUSTRY | 0 | Jul 20, 2026 | clinicaltrials |
| NCT03423628 | A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer | active not recruiting | Phase 1 | 159 | AstraZenecaINDUSTRY | 3 | Jul 17, 2026 | clinicaltrials |
| NCT06413706 | A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy | active not recruiting | Phase 2 | 45 | Eli Lilly and CompanyINDUSTRY | 10 | Jul 17, 2026 | clinicaltrials |
| NCT07225621 | Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma | recruiting | Phase 2 | 103 | Alpheus Medical, Inc.INDUSTRY | 1 | Jul 17, 2026 | clinicaltrials |
| NCT07710131 | Neurocognitive Assessment CNSL and LGG | not yet recruiting | N/A | 36 | Dana-Farber Cancer InstituteOTHER | 0 | Jul 17, 2026 | clinicaltrials |
| NCT07710690 | A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or Progressive High-grade Glioma | recruiting | Phase 1 | 24 | Neuregen Therapeutics Co., Ltd.INDUSTRY | 1 | Jul 17, 2026 | clinicaltrials |
| NCT07712328 | Randomized Controlled Clinical Study on the Prophylactic Intraoperative Use of Desmopressin in Complex Sellar Region Tumors(RCT-PIDST) | enrolling by invitation | Phase 4 | 152 | Zhaoyun ZhangOTHER | 1 | Jul 17, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Jul 30, 2026source: clinicaltrials