Clinical trial · Interventional
Listen Aphasia Pilot Study
LISTEN: Supporting Communication in Patients With Tumor-Related Aphasia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a feasibility and pilot study to refine and test LISTEN, an AI-based augmentative and alternative communication (AAC) smartphone app, integrated into the patient's personal electronic device, to augment and facilitate communication in patients with tumor-related aphasia (TRA) and their care partners. The study will assess the feasibility and acceptability of LISTEN in patients with TRA and their care partners.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aphasia | — | UNRESOLVED | — |
| Malignant Brain Tumor | Malignant Brain Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LISTEN (AI-based AAC smartphone app) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- OTHER
- label
- Arm 1
- description
- Refinement Phase - 10 patient-care-partner dyads (20 participants) will use the LISTEN prototype in a single session for usability testing.
- interventionNames
- Device: LISTEN (AI-based AAC smartphone app)
- type
- OTHER
- label
- Arm 2
- description
- Pre-pilot Phase - 10 patient-care-partner dyads (20 participants) will use LISTEN in real-world scenarios for iterative refinement.
- interventionNames
- Device: LISTEN (AI-based AAC smartphone app)
- type
- OTHER
- label
- Arm 3
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Patient inclusion criteria are as follows: * A histologically or cytologically confirmed primary or secondary brain tumor with expected ongoing deterioration in language as determined by their oncologist * Mild-to-moderate aphasia or other acquired communication disorder as determined by their oncologist or speech-language pathologist * ECOG Performance Status of ≤2 or Karnofsky Performance Status ≥60 * Expected overall survival of \>6 months * Ability to understand and the willingness to sign a written consent form * Age ≥18 years * Willingness to participate in study interviews and be recorded for the study (for monitoring of study fidelity) * Cancer survivors will also be included Care-partner inclusion criteria are as follows: * Identified by their patient as someone who is integral to their care * Age ≥18 years * Ability to understand and the willingness to sign a written consent form * Willingness to participate in study interviews and be recorded for the study (monitoring of study fidelity) Exclusion Criteria: Patient exclusion criteria are as follows: * Unable to read or respond to questions in English * Severe dysarthria as determined by their oncologist * Aphasia that is moderate-to-sever enough that the patient cannot consent without a proxy * Expected survival of ≤ 6 months * Severe cognitive impairment as determined by their oncologist Care-partner exclusion criteria are as follows: -Unable to read or respond to questions in English
References
Publications (0)
Data not yet available