Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
Loading cancer entity…
Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06115824 | New-diagnosed PCNSL Treated With Methotrexate (MTX) and Orelabrutinib-based Regimen | completed | — | 136 | Huashan HospitalOTHER | 1 | Sep 16, 2025 | clinicaltrials |
| NCT01351870 | Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma (PNET4)(SIOP-PNET-4) | completed | Phase 3 | 52 | Institut CurieOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT01811121 | MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS(RESECT) | completed | Phase 3 | 170 | Hospices Civils de LyonOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT03561870 | Olaparib in Recurrent IDH-mutant Glioma(OLAGLI) | completed | Phase 2 | 35 | Hospices Civils de LyonOTHER | 1 | Sep 12, 2025 | clinicaltrials |
| NCT06390579 | Building Research With Artificial Intelligence in Neuro-Ophthalmology(BRAIN) | completed | — | 693 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 1 | Sep 8, 2025 | clinicaltrials |
| NCT00186888 | Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma | completed | Phase 3 | 107 | St. Jude Children's Research HospitalOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT03050736 | Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression | completed | Phase 2 | 29 | Kintara Therapeutics, Inc.INDUSTRY | 1 | Sep 4, 2025 | clinicaltrials |
| NCT04324450 | Memory Neuroimaging in Children, Adolescents and Young Adults Following Pediatric Cancer(IMPALA) | completed | N/A | 60 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Sep 4, 2025 | clinicaltrials |
| NCT01165632 | Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma | completed | Early Phase 1 | 24 | Mayo ClinicOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT02656407 | Intraoperative Functional Ultrasound(FUSIMAGINE) | completed | N/A | 23 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Sep 2, 2025 | clinicaltrials |
| NCT05190315 | Chlorpromazine and Standard of Care in Glioblastoma | completed | Phase 1 | 10 | Mohammed MilhemOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT01478178 | Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma | completed | Phase 1 / Phase 2 | 55 | Kintara Therapeutics, Inc.INDUSTRY | 1 | Aug 29, 2025 | clinicaltrials |
| NCT02717962 | Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting | completed | Phase 2 | 118 | Kintara Therapeutics, Inc.INDUSTRY | 1 | Aug 29, 2025 | clinicaltrials |
| NCT03679754 | Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102 | completed | Phase 1 | 36 | Alaunos TherapeuticsINDUSTRY | 1 | Aug 28, 2025 | clinicaltrials |
| NCT04410133 | Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases(REVELATE) | completed | Phase 3 | 151 | Blue Earth DiagnosticsINDUSTRY | 1 | Aug 28, 2025 | clinicaltrials |
| NCT06582849 | Enhanced Assistance During Radiotherapy for Unmet Essential Needs(EARN) | completed | N/A | 33 | Washington University School of MedicineOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT05390814 | [18F]-Fludarabine PET/MRI in Primary Central Nervous System Lymphoma(FLUDALOC) | completed | Phase 1 | 10 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT01951482 | Pemetrexed/Platinum With or Without Bevacizumab in Brain Metastases From Patients With EGFR/ALK Negative Non-Squamous Non-small Cell Lung Cancer | completed | Phase 3 | 160 | Sun Yat-sen UniversityOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT02327078 | A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204) | completed | Phase 1 / Phase 2 | 307 | Incyte CorporationINDUSTRY | 2 | Aug 14, 2025 | clinicaltrials |
| NCT01063114 | Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma | completed | N/A | 90 | Massachusetts General HospitalOTHER | 1 | Aug 13, 2025 | clinicaltrials |
| NCT07120620 | PriCoTTF Study: TTFields Before and During Radiotherapy for Newly Diagnosed Glioblastoma(PriCoTTF) | completed | Phase 1 / Phase 2 | 33 | Sied KebirOTHER | 1 | Aug 13, 2025 | clinicaltrials |
| NCT03636477 | A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102 | completed | Phase 1 | 21 | Alaunos TherapeuticsINDUSTRY | 1 | Aug 12, 2025 | clinicaltrials |
| NCT04388475 | Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma | completed | Phase 2 | 57 | Oblato, Inc.INDUSTRY | 1 | Aug 12, 2025 | clinicaltrials |
| NCT05687474 | Baby Detect : Genomic Newborn Screening(BabyDetect) | completed | — | 6,824 | Centre Hospitalier Universitaire de LiegeOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT06150547 | A Study of Metabolic Agents Following Brain Radiation | completed | — | 5 | Mayo ClinicOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT06327048 | Application of Cognitive Training Based on the Remind Strategy in Glioma Patients With Cognitive Impairment | completed | N/A | 69 | YuanYuan MaOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT01931098 | Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab | completed | Phase 2 | 35 | National Cancer Institute (NCI)NIH | 1 | Aug 11, 2025 | clinicaltrials |
| NCT02681549 | Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer (NSCLC) | completed | Phase 2 | 41 | Yale UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT01295944 | Carboplatin and Bevacizumab for Recurrent Ependymoma | completed | Phase 2 | 35 | National Cancer Institute (NCI)NIH | 1 | Aug 5, 2025 | clinicaltrials |
| NCT03137888 | Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma | completed | Phase 2 | 30 | Emory UniversityOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT07094360 | Effect of Hydrotherapy on Children With Brain Tumor | completed | N/A | 50 | Cairo UniversityOTHER | 0 | Jul 30, 2025 | clinicaltrials |
| NCT05383872 | Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors | completed | N/A | 71 | InSightecINDUSTRY | 2 | Jul 28, 2025 | clinicaltrials |
| NCT03890952 | Translational Study of Nivolumab in Combination With Bevacizumab for Recurrent Glioblastoma | completed | Phase 2 | 40 | Ulrik LassenOTHER | 1 | Jul 24, 2025 | clinicaltrials |
| NCT05486923 | Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population(VERONICA) | completed | — | 450 | Huashan HospitalOTHER | 1 | Jul 24, 2025 | clinicaltrials |
| NCT04410367 | Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (PURSUE)(PURSUE) | completed | Phase 2 | 23 | Blue Earth DiagnosticsINDUSTRY | 1 | Jul 20, 2025 | clinicaltrials |
| NCT04227717 | Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine | completed | N/A | 9 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 18, 2025 | clinicaltrials |
| NCT03731455 | WISE Cortical Strip for Intraoperative Neurophysiological Monitoring(WIN) | completed | N/A | 32 | Wise S.r.l.INDUSTRY | 3 | Jul 17, 2025 | clinicaltrials |
| NCT02986178 | Lerapolturev in Recurrent Malignant Glioma | completed | Phase 2 | 121 | Istari Oncology, Inc.INDUSTRY | 1 | Jul 11, 2025 | clinicaltrials |
| NCT02611024 | Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors | completed | Phase 1 / Phase 2 | 316 | PharmaMarINDUSTRY | 6 | Jul 9, 2025 | clinicaltrials |
| NCT05169944 | Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors(PNOC025) | completed | Phase 1 | 13 | University of California, San FranciscoOTHER | 1 | Jul 9, 2025 | clinicaltrials |
| NCT03128047 | HUMC 1612: Optune NovoTTF-200A System | completed | Phase 1 | 7 | Hackensack Meridian HealthOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT03439332 | Multicentre Validation of How Vascular Biomarkers From Tumor Can Predict the Survival of the Patient With Glioblastoma(ONCOhabitats) | completed | — | 305 | Juan M Garcia-GomezOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT05229198 | ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas(ALBATROSS) | completed | — | 300 | Juan M Garcia-GomezOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT05375318 | BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels(BIOhabitats) | completed | — | 50 | Juan M Garcia-GomezOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT03345095 | A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma(MIRAGE) | completed | Phase 3 | 749 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 12 | Jul 1, 2025 | clinicaltrials |
| NCT02781792 | Temozolomide Chronotherapy for High Grade Glioma | completed | Phase 2 | 42 | Washington University School of MedicineOTHER | 1 | Jun 27, 2025 | clinicaltrials |
| NCT02514915 | Pre-operative Stereotactic Radiosurgery Followed by Resection for Brain Metastases | completed | N/A | 24 | Christopher WilkeOTHER | 1 | Jun 26, 2025 | clinicaltrials |
| NCT02601950 | A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma | completed | Phase 2 | 267 | Epizyme, Inc.INDUSTRY | 9 | Jun 22, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Sep 16, 2025source: clinicaltrials