Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05911230 | Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases(AiD-GLIO) | recruiting | N/A | 10 | University Hospital, Basel, SwitzerlandOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT06710249 | Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema(AFBTEdema) | recruiting | Phase 2 | 20 | Peter SiesjöOTHER | 1 | Jan 27, 2025 |
| clinicaltrials |
| NCT05968053 | Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)(DT-MiNi) | recruiting | — | 500 | Beijing Tiantan HospitalOTHER | 1 | Jan 23, 2025 | clinicaltrials |
| NCT06780592 | Vebreltinib Combined With Temozolomide for Glioblastoma (GBM) After Surgery | not yet recruiting | Phase 2 | 60 | Huashan HospitalOTHER | 0 | Jan 22, 2025 | clinicaltrials |
| NCT06787807 | Proteomic Analysis of Patients Undergoing Bariatric Surgery | not yet recruiting | N/A | 103 | Universidade Federal de PernambucoOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06097975 | A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma(NEO-GLITIPNI) | recruiting | Phase 1 | 18 | Universitair Ziekenhuis BrusselOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06720727 | Craniospinal Irradiation in Histone AlteRed Midline Glioma(CHARM) | recruiting | N/A | 32 | Tata Memorial CentreOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06782984 | Drug Response Testing and Repurposing Using Glioblastoma Organoid | recruiting | — | 150 | Chungnam National University HospitalOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06703255 | A Phase 2 Study of HX301 in Patients with High-grade Giloma | recruiting | Phase 1 / Phase 2 | 72 | Hangzhou Hanx Biopharmaceuticals, Ltd.INDUSTRY | 1 | Jan 15, 2025 | clinicaltrials |
| NCT03709680 | Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors | active not recruiting | Phase 2 | 128 | PfizerINDUSTRY | 14 | Jan 14, 2025 | clinicaltrials |
| NCT06679816 | Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine Tumors | recruiting | Phase 4 | 882 | Beijing Tiantan HospitalOTHER | 1 | Jan 14, 2025 | clinicaltrials |
| NCT06770335 | The FLaME Cognitive Rehabilitation Study for Childhood Brain Tumour(FLaME) | not yet recruiting | N/A | 36 | Great Ormond Street Hospital for Children NHS Foundation TrustOTHER | 1 | Jan 13, 2025 | clinicaltrials |
| NCT05528939 | Feasibility/Acceptability of Attentional-Control Training in Survivors(FAACTS) | recruiting | N/A | 50 | Children's National Research InstituteOTHER | 1 | Jan 10, 2025 | clinicaltrials |
| NCT06766591 | Ivonescimab Combined With Chemotherapy for the Treatment of Leptomeningeal Metastases Failed to EGFR-TKIs | not yet recruiting | N/A | 36 | Jiangsu Province Nanjing Brain HospitalOTHER | 0 | Jan 9, 2025 | clinicaltrials |
| NCT06764537 | Evaluation of in Vitro Antitumor Activity of GD2 CAR-T Cells in Glioblastoma(BOOSTCAR) | not yet recruiting | N/A | 18 | Central Hospital, Nancy, FranceOTHER | 1 | Jan 8, 2025 | clinicaltrials |
| NCT06757153 | Safety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients | recruiting | Early Phase 1 | 15 | Zhongnan HospitalOTHER | 1 | Jan 3, 2025 | clinicaltrials |
| NCT06753617 | Cryoablation of Brain Neoplasm | enrolling by invitation | N/A | 20 | Erasmus Medical CenterOTHER | 1 | Dec 31, 2024 | clinicaltrials |
| NCT04758533 | Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy(AloCELYVIR) | active not recruiting | Phase 1 / Phase 2 | 13 | Hospital Infantil Universitario Niño Jesús, Madrid, SpainOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06742593 | Study of MT027 in Patients with Brain, Meninges, and Spinal Cord Metastatic Solid Tumors | not yet recruiting | Phase 1 | 12 | Suzhou Maximum Bio-tech Co., Ltd.INDUSTRY | 1 | Dec 19, 2024 | clinicaltrials |
| NCT06740097 | Feasibility of Aspirate Tissue Monitoring in Neuro-oncological Surgery(ATM GBM INT) | recruiting | N/A | 50 | Kuopio University HospitalOTHER | 2 | Dec 18, 2024 | clinicaltrials |
| NCT06740955 | Hypofractionated Radiotherapy | recruiting | N/A | 420 | The First Hospital of Jilin UniversityOTHER | 1 | Dec 18, 2024 | clinicaltrials |
| NCT06737146 | Study of MT027 in Patients with Recurrent or Progressive High-grade Glioma | not yet recruiting | Phase 1 | 12 | Suzhou Maximum Bio-tech Co., Ltd.INDUSTRY | 1 | Dec 17, 2024 | clinicaltrials |
| NCT06737250 | NB02 (Poseltinib) Combined Rituximab and Lenalidomide in R/R PCNSL(POTENTIAL-P) | recruiting | Phase 2 | 33 | NOBO MedicineINDUSTRY | 1 | Dec 17, 2024 | clinicaltrials |
| NCT02824731 | Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn) | recruiting | N/A | 555 | Technische Universität DresdenOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT06736470 | Surgical Suction Aspirates Fluorescence Measurement(ATM GBM) | recruiting | — | 25 | Kuopio University HospitalOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT06116903 | Clinical Relevance of Detecting Molecular Abnormalities in Glial Tumor Exosomes(ExoGLIE) | recruiting | N/A | 60 | University Hospital, LimogesOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT04195139 | Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM(NUTMEG) | active not recruiting | Phase 2 | 103 | University of SydneyOTHER | 2 | Dec 11, 2024 | clinicaltrials |
| NCT05254197 | SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)(SOLOMON) | recruiting | — | 3,000 | Seoul National University HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT05776706 | Clinical Trial for the Validation of AR Based Neuronavigation System | not yet recruiting | N/A | 80 | Seoul National University HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT06172595 | FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma(FET PET in HGG) | recruiting | Phase 2 | 22 | Singapore General HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT06701838 | Osilodrostat Therapy and 11C-methionine PET to Improve Corticotroph Adenoma Detection(OPTIMAL) | not yet recruiting | — | 15 | Imperial College LondonOTHER | 0 | Dec 3, 2024 | clinicaltrials |
| NCT03395587 | Efficiency of Vaccination with Lysate-loaded Dendritic Cells in Patients with Newly Diagnosed Glioblastoma(GlioVax) | active not recruiting | Phase 2 | 136 | Heinrich-Heine University, DuesseldorfOTHER | 1 | Dec 2, 2024 | clinicaltrials |
| NCT05561374 | Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma | active not recruiting | Phase 1 | 16 | Oblato, Inc.INDUSTRY | 1 | Nov 29, 2024 | clinicaltrials |
| NCT05768919 | Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas | recruiting | Phase 1 / Phase 2 | 30 | SignPath Pharma, Inc.INDUSTRY | 1 | Nov 29, 2024 | clinicaltrials |
| NCT06161610 | Recurrent High Grade Glioma Treated by LITT(REGALITT) | recruiting | N/A | 135 | Beijing Tiantan HospitalOTHER | 1 | Nov 29, 2024 | clinicaltrials |
| NCT06704997 | Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation | active not recruiting | — | 10,000 | Tan Tock Seng HospitalOTHER | 1 | Nov 27, 2024 | clinicaltrials |
| NCT04648462 | Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology | recruiting | — | 1,500 | Maastricht Radiation OncologyOTHER | 1 | Nov 26, 2024 | clinicaltrials |
| NCT06705036 | Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions | recruiting | — | 20 | Shanghai Zhongshan HospitalOTHER | 1 | Nov 26, 2024 | clinicaltrials |
| NCT06705049 | Retrospective Study on Leptomeningeal Metastasis of Solid Tumors | enrolling by invitation | — | 107 | Shanghai Zhongshan HospitalOTHER | 1 | Nov 26, 2024 | clinicaltrials |
| NCT04233788 | Metabolic Characterization of Space Occupying Lesions of the Brain(FASTMRSI) | recruiting | — | 55 | Insel Gruppe AG, University Hospital BernOTHER | 1 | Nov 25, 2024 | clinicaltrials |
| NCT06362304 | 99mTc-CNDG SPECT/CT in Brain Tumors | recruiting | N/A | 30 | Peking Union Medical College HospitalOTHER | 1 | Nov 25, 2024 | clinicaltrials |
| NCT06702826 | Cadonilimab Combined With Stereotactic Radiotherapy as Second-line Treatment for Brain Metastases | recruiting | Phase 2 | 20 | Rongrong ZhouOTHER | 1 | Nov 25, 2024 | clinicaltrials |
| NCT04868396 | Patient-derived Glioma Stem Cell Organoids | active not recruiting | — | 60 | Maastricht Radiation OncologyOTHER | 1 | Nov 20, 2024 | clinicaltrials |
| NCT06160206 | Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma | recruiting | Phase 2 | 134 | Academic and Community Cancer Research UnitedOTHER | 1 | Nov 19, 2024 | clinicaltrials |
| NCT06043765 | Reducing Cognitive Impairment in Glioma with Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training(TRUE-GRIT) | recruiting | N/A | 16 | Linda DouwOTHER | 1 | Nov 18, 2024 | clinicaltrials |
| NCT06684899 | Optimizing Cytokine-Induced Killer Cells in Glioblastoma Patients(KillGlio) | not yet recruiting | — | 40 | IRCCS San RaffaeleOTHER | 0 | Nov 14, 2024 | clinicaltrials |
| NCT06640582 | TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas(BAH2472) | recruiting | Phase 1 / Phase 2 | 85 | Essen BiotechOTHER | 1 | Nov 5, 2024 | clinicaltrials |
| NCT01985087 | A Study Using Radiation Therapy and Temozolomide to Treat Glioblastoma in Patients Over 70 | active not recruiting | Phase 1 / Phase 2 | 18 | University of LouisvilleOTHER | 1 | Oct 31, 2024 | clinicaltrials |
| NCT05118776 | Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM | active not recruiting | Phase 3 | 136 | Ascletis Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Oct 31, 2024 | clinicaltrials |
| NCT06664190 | Pre-operative Surgical Difficulty Stratification Using Predicted Tumor Perfusion and Consistency | active not recruiting | — | 200 | Huashan HospitalOTHER | 1 | Oct 29, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Jan 29, 2025source: clinicaltrials