Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06690216 | Evaluation of [18F]AlF-NOTA-PCP2 PET/CT for PD-L1 Detection in Malignant Tumors(PD-L1-PET) | enrolling by invitation | Phase 1 / Phase 2 | 100 | Man HuOTHER | 1 | Mar 30, 2025 | clinicaltrials |
| NCT06901817 | A Study of the Safety and Efficacy of Pemetrexed Combined with Nivolumab Via Intraventricular Injection for the Treatment of Refractory Non-squamous Non-small Cell Lung Cancer with Leptomeningeal Metastases | recruiting | Phase 2 | 97 | Shanghai Cancer Hospital, ChinaOTHER | 1 |
| Mar 30, 2025 |
| clinicaltrials |
| NCT06901999 | Methotrexate or Thiotepa Combined With R-CHOP and Orelabrutinib in CNSL Patients | not yet recruiting | Phase 2 | 23 | Ruijin HospitalOTHER | 0 | Mar 30, 2025 | clinicaltrials |
| NCT06678867 | The Use of 5-ALA in Paediatric Patients With High Grade Brain Tumours(P5A) | not yet recruiting | Phase 2 | 80 | University College, LondonOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT01906385 | Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT) | recruiting | Phase 1 / Phase 2 | 55 | Plus TherapeuticsINDUSTRY | 1 | Mar 26, 2025 | clinicaltrials |
| NCT05034497 | Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases(ReSPECT-LM) | active not recruiting | Phase 1 | 18 | Plus TherapeuticsINDUSTRY | 1 | Mar 26, 2025 | clinicaltrials |
| NCT06323408 | Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas(BZKF-AYA) | not yet recruiting | — | 72 | University Hospital RegensburgOTHER | 0 | Mar 25, 2025 | clinicaltrials |
| NCT06894238 | Electroencephalogram Predicts Post-operative Delirium(EPOD) | recruiting | — | 137 | Beijing Sanbo Brain HospitalOTHER | 1 | Mar 25, 2025 | clinicaltrials |
| NCT06887673 | Lipid Mediators & Cancer: Montelukast, SPM, and Almonds | not yet recruiting | Early Phase 1 | 56 | University of South FloridaOTHER | 1 | Mar 20, 2025 | clinicaltrials |
| NCT06869746 | Swiss Spinal Tumor Registry (Swiss-STR)(SSTR) | recruiting | — | 250 | Luzerner KantonsspitalOTHER | 1 | Mar 19, 2025 | clinicaltrials |
| NCT03496402 | Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO)(MICCHADO) | active not recruiting | N/A | 600 | Institut CurieOTHER | 1 | Mar 18, 2025 | clinicaltrials |
| NCT06876688 | Relma-cel Followed by Tislelizumab for the Treatment of Relapsed/Refractory CNS Large B-Cell Lymphoma | recruiting | Phase 2 | 30 | Ruijin HospitalOTHER | 1 | Mar 14, 2025 | clinicaltrials |
| NCT05793034 | Predictive Factors for Survival in Aggressive Meningiomas(23Men) | recruiting | N/A | 250 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT05941234 | Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma(IPerGlioGEM) | recruiting | N/A | 120 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06054529 | Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients(GBM-FLUX2) | active not recruiting | — | 2 | AdventHealth Translational Research InstituteOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06781372 | Patient's Derived Organoids for Drug Screening in Glioblastoma(GlioPDO) | not yet recruiting | N/A | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06408428 | Glioma Intraoperative MicroElectroCorticoGraphy(MicroECoGG) | not yet recruiting | N/A | 50 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Mar 12, 2025 | clinicaltrials |
| NCT06607029 | Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection | recruiting | N/A | 170 | Beijing Tiantan HospitalOTHER | 1 | Mar 11, 2025 | clinicaltrials |
| NCT05274919 | Vascular Signature Mapping of Brain Tumor Genotypes(VASIM) | recruiting | — | 180 | Leiden University Medical CenterOTHER | 1 | Mar 10, 2025 | clinicaltrials |
| NCT05769660 | A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM) | recruiting | Phase 1 | 12 | BeyondBio Inc.INDUSTRY | 1 | Mar 10, 2025 | clinicaltrials |
| NCT06867978 | Multi-center Study on CCeLL-In Vivo's Clinical Efficacy for Intraoperative Brain Tumor Diagnosis.(PRECISION) | not yet recruiting | Phase 1 | 100 | VPIX MedicalINDUSTRY | 0 | Mar 10, 2025 | clinicaltrials |
| NCT06863064 | Brain Tumor Surgery and Postoperative Delirium | not yet recruiting | N/A | 140 | Kaohsiung Medical University Chung-Ho Memorial HospitalOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT06643000 | Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis | recruiting | N/A | 60 | Henan Cancer HospitalOTHER_GOV | 1 | Mar 6, 2025 | clinicaltrials |
| NCT06861218 | Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal Metastases | not yet recruiting | Phase 2 | 42 | Zhejiang Cancer HospitalOTHER | 1 | Mar 6, 2025 | clinicaltrials |
| NCT05341739 | A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases | active not recruiting | N/A | 20 | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)OTHER | 1 | Mar 5, 2025 | clinicaltrials |
| NCT05565326 | Response Assessment During MR-guided Radiation Therapy for Glioblastoma(MARGA) | recruiting | — | 20 | University of ZurichOTHER | 1 | Mar 3, 2025 | clinicaltrials |
| NCT03452579 | Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBM | active not recruiting | Phase 2 | 90 | David PeereboomOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT06852001 | Efficacy of the RayerKnife X Stereotactic Radiotherapy System in the Treatment of Brain Metastases | not yet recruiting | N/A | 34 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Feb 28, 2025 | clinicaltrials |
| NCT06853080 | Feasibility of Using Bortezomib With or Without Chemotherapy in Patients With Atypical Teratoid/Rhabdoid Tumors | active not recruiting | Phase 2 | 6 | Taipei Medical UniversityOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT04590664 | Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma | recruiting | Phase 1 / Phase 2 | 24 | Emory UniversityOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT04903678 | Intrathecal Chemotherapy for Central Nervous System Metastasis in Retinoblastoma | recruiting | N/A | 18 | Eye & ENT Hospital of Fudan UniversityOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT06845020 | CSF Proteomic Characterization of Glioblastomas | not yet recruiting | — | 15 | Univeridad Autonoma de GuadalajaraOTHER | 0 | Feb 25, 2025 | clinicaltrials |
| NCT05231655 | Ex VIvo DEtermiNed Cancer Therapy(EVIDENT) | recruiting | — | 600 | Sheffield Teaching Hospitals NHS Foundation TrustOTHER | 1 | Feb 24, 2025 | clinicaltrials |
| NCT06835426 | High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins | recruiting | N/A | 150 | Algemeen Ziekenhuis Maria MiddelaresOTHER | 1 | Feb 19, 2025 | clinicaltrials |
| NCT06831773 | Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma | recruiting | N/A | 23 | Gansu Wuwei Tumor HospitalOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT06832267 | Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) Regimen As First-line Therapy for PCNS DLBCL | recruiting | N/A | 44 | Zhejiang Cancer HospitalOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT06832384 | Intensive Physiotherapy in Children Affected by Posterior Fossa Tumors | recruiting | — | 40 | IRCCS Eugenio MedeaOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT03181477 | Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas(Glio-SIB-Up) | active not recruiting | N/A | 67 | Centre Georges Francois LeclercOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06000787 | MCT for the Harvard/UCSF ROBIN Center | recruiting | N/A | 47 | Brigham and Women's HospitalOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06830356 | Somatostatin Receptor PET Imaging to Guide Radiotherapy Dose Escalation in High Risk Meningiomas.(SPIDER-MEN) | recruiting | N/A | 53 | Centro di Riferimento Oncologico - AvianoOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06830421 | Adjusted High-dose Chemotherapy With Autologous Stem Cell Transplant vs. Conventional Immunochemotherapy in Elderly PCNSL Patients(PRIMA-CNS) | recruiting | Phase 3 | 340 | University Hospital FreiburgOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT04881032 | AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma(NANO-GBM) | active not recruiting | Phase 1 / Phase 2 | 66 | Centre Jean PerrinOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT06140875 | Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With Radiochemotherapy and Maintenance Chemotherapy in Patients With Glioblastoma (Brain-RF) | recruiting | N/A | 26 | Charite University, Berlin, GermanyOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT03696680 | Stereotactic Radiotherapy for Cerebral Metastases with Recent Hemorrhagic Signal(STEREO-HBM) | recruiting | Phase 2 | 46 | Centre Francois BaclesseOTHER | 1 | Feb 11, 2025 | clinicaltrials |
| NCT05473923 | PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas | active not recruiting | Early Phase 1 | 30 | Beijing Tiantan HospitalOTHER | 1 | Feb 11, 2025 | clinicaltrials |
| NCT06814353 | Intraoperatively Observed Site of Origin and Growth Pattern of Medulloblastoma(ISOP) | enrolling by invitation | — | 100 | Christian DorferOTHER | 3 | Feb 7, 2025 | clinicaltrials |
| NCT04962672 | Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study | recruiting | N/A | 40 | University Health Network, TorontoOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT06113705 | Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study. | recruiting | N/A | 75 | Istituto Clinico HumanitasOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT03382158 | International PPB/DICER1 Registry | recruiting | — | 3,400 | Children's Hospitals and Clinics of MinnesotaOTHER | 1 | Jan 30, 2025 | clinicaltrials |
| NCT06801730 | Irinotecan Liposomes Combined With Bevacizumab in the Treatment of Recurrent Glioma(NALIRIBVRG) | recruiting | Phase 2 | 38 | Zhifeng Tian,MDOTHER | 1 | Jan 30, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Mar 30, 2025source: clinicaltrials