Clinical trial · Observational
Electroencephalogram Predicts Post-operative Delirium
Frontal-temporal EEG During Anesthesia Recovery Predicts Postoperative Delirium in Neurosurgery: a Single-center, Prospective, Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to investigate the predictive value of sub-hairline electroencephalography (EEG) during anesthesia recovery for postoperative delirium (POD). The main question to be answered is: * Can sub-hairline EEG measured during anesthesia recovery serve as a reliable predictor of POD? Adult patients undergoing elective craniotomy and admitted to the ICU will be enrolled. Sub-hairline EEG will be monitored until ICU discharge.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor Adult | Brain Neoplasm | ALIAS | 0.85 |
| Delirium - Postoperative | — | UNRESOLVED | — |
| Neurosurgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sub-hairline EEG Monitoring | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- POD group
- description
- Patients who develop POD within seven days after surgery, as assessed using validated screening tools (CAM-ICU, DOSS, FMSE)
- interventionNames
- Diagnostic Test: Sub-hairline EEG Monitoring
- label
- Non-POD group
- description
- Patients who do not develop POD within the seven-day postoperative period.
- interventionNames
- Diagnostic Test: Sub-hairline EEG Monitoring
Primary outcomes (1)
- measure
- Incidence of Postoperative Delirium (POD)
- timeFrame
- Within 7 days post-surgery
- description
- The primary outcome of this study is to assess whether sub-hairline EEG parameters recorded during anesthesia recovery can reliably predict the incidence of postoperative delirium (POD) within the first 7 days following elective craniotomy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 years * Planned elective neurosurgical surgery * ASA physical status I-II * Signed informed consent Exclusion Criteria: * Known neurological or psychiatric disorders (e.g., epilepsy, Parkinson's disease) * Preoperative cognitive impairment (MMSE score \< 24) * Long-term use of central nervous system drugs (e.g., antidepressants, antipsychotics) * Language barriers * History of craniotomy within the last 12 months * Inability to place frontal-temporal electrodes due to conditions such as frontal skin injury, severe agitation, or a coronal incision for surgery * Pregnant or breastfeeding women
References
Publications (0)
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