Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01378481 | High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma | terminated | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT00761280 | Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma(SAPPHIRE) | terminated | Phase 3 | 27 | Isarna Therapeutics GmbHINDUSTRY | 16 | Nov 14, 2014 |
| clinicaltrials |
| NCT01088763 | Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia | terminated | Phase 1 | 129 | National Cancer Institute (NCI)NIH | 2 | Nov 5, 2014 | clinicaltrials |
| NCT01549392 | Imaging Study of Glioblastomas Treated With Avastin | terminated | N/A | 3 | London Health Sciences CentreOTHER | 1 | Sep 15, 2014 | clinicaltrials |
| NCT00897377 | Treatment Strategy for Low-grade Gliomas | terminated | Phase 3 | 500 | Sun Yat-sen UniversityOTHER | 1 | Aug 5, 2014 | clinicaltrials |
| NCT00589095 | Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities | terminated | — | 5 | Yale UniversityOTHER | 1 | Jul 2, 2014 | clinicaltrials |
| NCT00387426 | Sunitinib in Treating Patients With Idiopathic Myelofibrosis | terminated | Phase 2 | 14 | National Cancer Institute (NCI)NIH | 1 | May 28, 2014 | clinicaltrials |
| NCT01515085 | MRI-Guided Laser Induced Thermal Therapy(LITT) | terminated | — | 1 | Rutgers, The State University of New JerseyOTHER | 1 | May 22, 2014 | clinicaltrials |
| NCT01403285 | Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma | terminated | Phase 1 | 6 | Immatics Biotechnologies GmbHINDUSTRY | 1 | May 19, 2014 | clinicaltrials |
| NCT00121420 | Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases | terminated | Phase 2 | 45 | Pharmacyclics LLC.INDUSTRY | 2 | May 9, 2014 | clinicaltrials |
| NCT00636805 | Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With Bevacizumab | terminated | Phase 2 | 63 | Duke UniversityOTHER | 1 | Apr 1, 2014 | clinicaltrials |
| NCT01348607 | Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer Therapy | terminated | Phase 2 | 1 | University of South FloridaOTHER | 0 | Feb 21, 2014 | clinicaltrials |
| NCT01407341 | Beta-Tricalcium Phosphate Bone Graft in Treating Patients Undergoing Surgery For Metastatic Spine Cancer | terminated | Phase 1 | 1 | University of Southern CaliforniaOTHER | 1 | Feb 6, 2014 | clinicaltrials |
| NCT01600742 | Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis | terminated | Phase 2 | 4 | National Taiwan University HospitalOTHER | 1 | Jan 9, 2014 | clinicaltrials |
| NCT01400958 | Nuvigil or Placebo in Newly Diagnosed Malignant Glioma | terminated | Phase 2 | 6 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 16, 2013 | clinicaltrials |
| NCT00107471 | Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma | terminated | Phase 1 / Phase 2 | 7 | Children's Oncology GroupNETWORK | 4 | Dec 10, 2013 | clinicaltrials |
| NCT00003292 | S9624 Ifosfamide in Treating Patients With Meningeal Tumors | terminated | Phase 2 | 7 | SWOG Cancer Research NetworkNETWORK | 4 | Nov 8, 2013 | clinicaltrials |
| NCT01652768 | PRESENCE Project: An Early Palliative Care Intervention in Brain Tumors | terminated | N/A | 1 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 29, 2013 | clinicaltrials |
| NCT01205334 | Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme(COGLI) | terminated | Phase 1 / Phase 2 | 2 | Baylor College of MedicineOTHER | 1 | Aug 26, 2013 | clinicaltrials |
| NCT01369121 | Tolerability Study of Xerecept® in Pediatric Patients | terminated | Phase 1 / Phase 2 | 15 | Celtic Pharma Development ServicesINDUSTRY | 1 | Jul 30, 2013 | clinicaltrials |
| NCT00488644 | Combined Levothyroxine/Liothyronine Supplementation in Hypothyroid Patients With Brain Tumors | terminated | N/A | 12 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 24, 2013 | clinicaltrials |
| NCT01095094 | Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma | terminated | Phase 2 | 19 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 10, 2013 | clinicaltrials |
| NCT00387894 | Erlotinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma | terminated | Phase 2 | 6 | Michael PradosOTHER | 1 | Jun 4, 2013 | clinicaltrials |
| NCT00005812 | Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma | terminated | Phase 2 | 12 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | May 14, 2013 | clinicaltrials |
| NCT00815152 | Coping With High Grade Glioma | terminated | N/A | 14 | Duke UniversityOTHER | 1 | May 6, 2013 | clinicaltrials |
| NCT01011231 | Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Imaging (MRI) Spectroscopy for Recurrent Glioma(GKS) | terminated | Phase 2 | 1 | University of California, San FranciscoOTHER | 1 | May 6, 2013 | clinicaltrials |
| NCT00650949 | Efficacy Study of CYT997 in Combination With Carboplatin in Glioblastoma | terminated | Phase 1 / Phase 2 | 20 | Gilead SciencesINDUSTRY | 1 | May 3, 2013 | clinicaltrials |
| NCT00959946 | Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer | terminated | Phase 1 / Phase 2 | 32 | PfizerINDUSTRY | 6 | Feb 22, 2013 | clinicaltrials |
| NCT00696943 | 18F ML-10 for Early Detection of Response of Brain Metastases to SRS | terminated | Phase 2 | 1 | Aposense Ltd.INDUSTRY | 0 | Feb 15, 2013 | clinicaltrials |
| NCT00735436 | A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM) | terminated | Phase 2 | 18 | Duke UniversityOTHER | 1 | Feb 11, 2013 | clinicaltrials |
| NCT01269411 | RO4929097 in Treating Patients With Recurrent Invasive Gliomas | terminated | Phase 1 | 22 | National Cancer Institute (NCI)NIH | 1 | Feb 7, 2013 | clinicaltrials |
| NCT00005856 | Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | terminated | Phase 1 / Phase 2 | 59 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00006773 | Bortezomib in Treating Patients With Recurrent Glioma | terminated | Phase 1 | 42 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00075491 | Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma Multiforme | terminated | Phase 2 | 42 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00036855 | Radiolabeled Monoclonal Antibody With or Without Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Lymphoma | terminated | Phase 1 | 36 | National Cancer Institute (NCI)NIH | 1 | Jan 17, 2013 | clinicaltrials |
| NCT00110032 | Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors | terminated | Phase 1 | 46 | National Cancer Institute (NCI)NIH | 1 | Jan 16, 2013 | clinicaltrials |
| NCT00430079 | Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma | terminated | N/A | 48 | National Cancer Institute (NCI)NIH | 1 | Jan 16, 2013 | clinicaltrials |
| NCT00720837 | Magnetic Resonance Temperature Imaging & Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors | terminated | N/A | 6 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 11, 2012 | clinicaltrials |
| NCT00717275 | Study of Temozolomide to Treat Newly Diagnosed Brain Metastases | terminated | Phase 2 | 3 | University of FloridaOTHER | 1 | Oct 1, 2012 | clinicaltrials |
| NCT00104936 | Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by Surgery | terminated | Phase 3 | 9 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 3 | Sep 24, 2012 | clinicaltrials |
| NCT00948389 | Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM) | terminated | Phase 1 / Phase 2 | 28 | Bristol-Myers SquibbINDUSTRY | 4 | Aug 31, 2012 | clinicaltrials |
| NCT00272870 | Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy | terminated | Phase 1 | 1 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Aug 29, 2012 | clinicaltrials |
| NCT00415467 | Treatment of Resectable Malignant Brain Tumors | terminated | Phase 4 | 13 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 2, 2012 | clinicaltrials |
| NCT00477503 | Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA | terminated | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 1, 2012 | clinicaltrials |
| NCT00629187 | Safety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) Malignancy(CN-306) | terminated | Phase 1 | 2 | Tufts Medical CenterOTHER | 1 | Apr 27, 2012 | clinicaltrials |
| NCT00389090 | A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma | terminated | Phase 2 | 32 | Keryx / AOI Pharmaceuticals, Inc.INDUSTRY | 1 | Feb 9, 2012 | clinicaltrials |
| NCT00508456 | Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM | terminated | Phase 1 | 18 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 16, 2012 | clinicaltrials |
| NCT01105988 | Evaluating Tumor Pseudoprogression With FLT-PET and MRI | terminated | Early Phase 1 | 2 | Massachusetts General HospitalOTHER | 1 | Jan 6, 2012 | clinicaltrials |
| NCT00790452 | Aspirin Prophylaxis for Venous Thromboembolism in Glioblastoma | terminated | Phase 2 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 8, 2011 | clinicaltrials |
Data updated 23 days agoSource updated Dec 23, 2014source: clinicaltrials