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B-Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Hematopoietic and Lymphoid Cell Neoplasm
Lymphocytic Neoplasm
B-Cell Neoplasm

Hematologic Malignancy

B-Cell Neoplasm

CI-CAN-00000470Explore in graph →

HematologicNon-malignant2,097 active trials46 approved drugs301 evidence items

NCIt: C27907

Overview
Statistics
Survival
Genomics29
Variants & evidence301
Drugs45
Trials7500
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (305)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 176–200 of 305 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

The genomic landscape of pediatric acute lymphoblastic leukemia.
· Nat Genet · 2022 · PMID 36050548 · validated civic_curation pubmed
Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.
· Nat Genet · 2016 · PMID 27019113 · validated civic_curation pubmed
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.
· Nat Genet · 2016 · PMID 27776115 · validated cbioportal_study pubmed
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.
· Nat Commun · 2016 · PMID 27265895 · validated civic_curation pubmed
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.
· Blood · 2011 · PMID 21487109 · validated civic_curation pubmed
Distinct molecular profile of IRF4-rearranged large B-cell lymphoma.
· Blood · 2020 · PMID 31738823 · validated civic_curation pubmed
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.
· Cancer Cell · 2012 · PMID 22897847 · validated civic_curation pubmed
Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Study Group.

Showing 176–200 of 305 publications

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· Blood · 1997 · PMID 9226156 · validated civic_curation pubmed

The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.

· Blood · 1995 · PMID 7780150 · validated civic_curation pubmed

TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis.

· Leukemia · 1995 · PMID 8609706 · validated civic_curation pubmed

B acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: a clinically aggressive subset of disease.

· Mod Pathol · 2014 · PMID 24030742 · validated civic_curation pubmed

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.

· Cancer Cell · 2016 · PMID 26859458 · validated civic_curation pubmed

The MLL recombinome of acute leukemias in 2017.

· Leukemia · 2018 · PMID 28701730 · validated civic_curation pubmed

Multilineage involvement in KMT2A-rearranged B acute lymphoblastic leukaemia: cell-of-origin, biology, and clinical implications.

· Histopathology · 2024 · PMID 38686611 · validated civic_curation pubmed

PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome.

· Leukemia · 2025 · PMID 39702796 · validated civic_curation pubmed

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways.

· Proc Natl Acad Sci U S A · 2008 · PMID 18765795 · validated civic_curation pubmed

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.

· Nature · 2011 · PMID 21796119 · validated civic_curation pubmed

Targeting the BRAF V600E mutation in multiple myeloma.

· Cancer Discov · 2013 · PMID 23612012 · validated civic_curation pubmed

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.

· Blood · 2012 · PMID 22210878 · validated civic_curation pubmed

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

· J Exp Med · 2011 · PMID 21670202 · validated civic_curation pubmed

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

· Blood · 2014 · PMID 24366361 · validated civic_curation pubmed

p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression.

· Blood · 1993 · PMID 8241511 · validated civic_curation pubmed

Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: results from the LRF CLL4 trial.

· J Clin Oncol · 2011 · PMID 21483000 · validated civic_curation pubmed

Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia.

· Cancer Res · 1998 · PMID 9788599 · validated civic_curation pubmed

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.

· Blood · 2016 · PMID 27226433 · validated civic_curation pubmed