Subtype
Anorectal Neoplasm
CI-CAN-00001814Explore in graph →
Non-malignant504 active trials1 approved drugs6 evidence items
- NCIt
- C215222
Loading cancer entity…
Subtype
CI-CAN-00001814Explore in graph →
Clinical trials
2,046 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06901856 | Endoscopic Resection for Small Rectal Neuroendocrine Tumors | not yet recruiting | N/A | 120 | Guangdong Provincial People's HospitalOTHER | 0 | Mar 30, 2025 | clinicaltrials |
| NCT06872606 | Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer(SCRIPBOT) | not yet recruiting | Phase 2 | 33 | Sir Run Run Shaw HospitalOTHER |
| 1 |
| Mar 12, 2025 |
| clinicaltrials |
| NCT06105203 | RATME Vs LATME in Middle and Low Rectal Cancer | not yet recruiting | N/A | 1,026 | The First Hospital of Jilin UniversityOTHER | 1 | Feb 19, 2025 | clinicaltrials |
| NCT06783153 | Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients | not yet recruiting | Phase 1 / Phase 2 | 80 | Mansoura UniversityOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06760520 | Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 40 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Jan 8, 2025 | clinicaltrials |
| NCT06751394 | Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer(TRACER) | not yet recruiting | Phase 2 | 44 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06746298 | A Prospective Study of Expression Profiling-based Assessment of the Efficacy of Neoadjuvant Therapy for Rectal Cancer | not yet recruiting | — | 118 | Shanghai Minimally Invasive Surgery CenterOTHER | 0 | Dec 24, 2024 | clinicaltrials |
| NCT06665087 | CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC | not yet recruiting | Phase 2 | 110 | Fudan UniversityOTHER | 0 | Oct 30, 2024 | clinicaltrials |
| NCT06652412 | CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRC | not yet recruiting | Phase 2 | 124 | Fudan UniversityOTHER | 0 | Oct 28, 2024 | clinicaltrials |
| NCT06619743 | HPV Infection and Vaginal Microecology in Immunosuppressed Women | not yet recruiting | — | 10,000 | Lan ZhuOTHER | 0 | Oct 1, 2024 | clinicaltrials |
| NCT06616870 | Study of the Predictive and Prognostic Role of Pharmacogenetic and Radiogenic Variants on the Response to Neoadjuvant Chemoradiation Therapy in Patients With Locally Advanced Rectal Cancer(IGLarc) | not yet recruiting | — | 460 | Centro di Riferimento Oncologico - AvianoOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT06613399 | Multi-Technology Integrated Total Mesorectal Excision Versus Conventional Total Mesorectal Excision for the Treatment of Middle and Distal Rectal Cancer. | not yet recruiting | N/A | 324 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Sep 26, 2024 | clinicaltrials |
| NCT06599827 | Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC(iMHRT-LARC) | not yet recruiting | Phase 2 | 54 | Shanghai Zhongshan HospitalOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06567756 | Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer | not yet recruiting | N/A | 84 | Changhai HospitalOTHER | 0 | Aug 23, 2024 | clinicaltrials |
| NCT06521827 | The Role of Short Course of Palliative Radiation in Metastatic Cancer Rectum | not yet recruiting | N/A | 49 | Assiut UniversityOTHER | 0 | Jul 26, 2024 | clinicaltrials |
| NCT06504875 | Application of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal Cancer | not yet recruiting | — | 23 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Jul 17, 2024 | clinicaltrials |
| NCT06505551 | Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma | not yet recruiting | Phase 1 / Phase 2 | 66 | SCG Cell Therapy Pte. Ltd.INDUSTRY | 0 | Jul 17, 2024 | clinicaltrials |
| NCT06450574 | Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Ttransanal Endoscopic Microsurgery in T1 N0, M0 Rectal Cancer (TAUTEM-T1 Study)(TAUTEM-T1) | not yet recruiting | Phase 3 | 106 | Corporacion Parc TauliOTHER | 0 | Jun 10, 2024 | clinicaltrials |
| NCT06443671 | Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer(PKUCH-R09) | not yet recruiting | Phase 2 / Phase 3 | 132 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 5, 2024 | clinicaltrials |
| NCT06390982 | Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study | not yet recruiting | Phase 2 | 46 | Fudan UniversityOTHER | 0 | Apr 30, 2024 | clinicaltrials |
| NCT06255379 | Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 52 | Guangzhou University of Traditional Chinese MedicineOTHER | 1 | Apr 29, 2024 | clinicaltrials |
| NCT06358053 | CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers | not yet recruiting | Phase 1 | 24 | Corregene Biotechnology Co., LtdINDUSTRY | 0 | Apr 10, 2024 | clinicaltrials |
| NCT06304545 | Treatment of Rectal Cancer With Long-term Concurrent Chemoradiotherapy Combined With Camrelizumab | not yet recruiting | Phase 2 | 48 | Harbin Medical UniversityOTHER | 0 | Mar 12, 2024 | clinicaltrials |
| NCT05807646 | Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients. | not yet recruiting | N/A | 268 | Sichuan Cancer Hospital and Research InstituteOTHER | 0 | Feb 15, 2024 | clinicaltrials |
| NCT06225609 | No Stoma VS Ghost Stoma in Patients Undergoing Total Mesorectal Excision for Rectal Cancer | not yet recruiting | N/A | 500 | fan liOTHER | 0 | Jan 26, 2024 | clinicaltrials |
| NCT04889742 | Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors(HETERERO) | not yet recruiting | Phase 2 | 110 | Charite University, Berlin, GermanyOTHER | 1 | Dec 26, 2023 | clinicaltrials |
| NCT06097416 | Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer | not yet recruiting | Phase 3 | 100 | St. James's Hospital, IrelandOTHER | 0 | Oct 25, 2023 | clinicaltrials |
| NCT06066931 | Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE | not yet recruiting | N/A | 150 | Kuban State Medical UniversityOTHER | 0 | Oct 10, 2023 | clinicaltrials |
| NCT06053996 | Hepatopulmonary Radio-sterilization With Immunotherapy(TROS-8) | not yet recruiting | N/A | 44 | Sheba Medical CenterOTHER_GOV | 1 | Sep 26, 2023 | clinicaltrials |
| NCT06035133 | Treatment of Low Locally Advanced Rectal Cancer With Radiotherapy Removal TNT Plus Neoadjuvant Therapy | not yet recruiting | N/A | 213 | Tang-Du HospitalOTHER | 0 | Sep 13, 2023 | clinicaltrials |
| NCT06014944 | Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody(PMMR/MSS) | not yet recruiting | Phase 2 | 30 | Changhai HospitalOTHER | 0 | Aug 31, 2023 | clinicaltrials |
| NCT05998122 | Total Neoadjuvant Chemoradiotherapy Plus Anti-PD-1 in Subperitoneal Patients With Locally Advanced Rectal CancerPatients With Locally Advanced Rectal Cancer: A Prospective, Single Arm, Exploratory Study | not yet recruiting | Phase 2 | 45 | The First Hospital of Jilin UniversityOTHER | 1 | Aug 18, 2023 | clinicaltrials |
| NCT05969847 | Organ Preservation Following Enverolimab-based Total Neoadjuvant Therapy for Locally Advanced Very Low Rectal Cancer(TRACE-LE) | not yet recruiting | Phase 2 | 72 | 池畔OTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05970900 | Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GIST(PIRKER) | not yet recruiting | Phase 3 | 23 | Fujian Medical University Union HospitalOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05807984 | Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion | not yet recruiting | Phase 2 | 31 | Xin CaiOTHER | 1 | Apr 11, 2023 | clinicaltrials |
| NCT05794750 | Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC(AK104-IIT-13)(AK104-IIT-13) | not yet recruiting | Phase 2 | 50 | JIN JINGOTHER | 0 | Apr 6, 2023 | clinicaltrials |
| NCT05671809 | Effects of Different Treatment for Anorectal Function of Patients With Rectal Cancer(ARF-RC) | not yet recruiting | — | 402 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jan 5, 2023 | clinicaltrials |
| NCT05359393 | A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis(Miracle-1) | not yet recruiting | Phase 2 | 52 | Fudan UniversityOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT04893876 | The OPERa Study: Evaluating QoL After Rectal Cancer Surgery | not yet recruiting | — | 1,200 | Jewish General HospitalOTHER | 0 | Aug 18, 2022 | clinicaltrials |
| NCT05484024 | Short-course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 / Phase 3 | 588 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 2, 2022 | clinicaltrials |
| NCT05429216 | Endoscopic Resection for Small Rectal Neuroendocrine Tumors | not yet recruiting | N/A | 102 | Nanfang Hospital, Southern Medical UniversityOTHER | 0 | Jul 1, 2022 | clinicaltrials |
| NCT04200027 | Robotic vs. TaTME Rectal Surgery (ROTA STUDY)(ROTA) | not yet recruiting | — | 330 | Odense University HospitalOTHER | 2 | Aug 3, 2021 | clinicaltrials |
| NCT04443543 | An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 222 | Fudan UniversityOTHER | 1 | Jun 30, 2020 | clinicaltrials |
| NCT03975049 | Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer | not yet recruiting | Phase 3 | 933 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jun 5, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Mar 30, 2025source: clinicaltrials