Acute Myeloid Leukemia with FUS-ERG — Variants & evidence

Acute Myeloid Leukemia with FUS-ERG — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

3 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–3 of 3 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
ERG Fusion3
(diagnostic)	Diagnostic	B	Supports Positive	4	accepted	EID12321 This study investigates the diagnostic importance of the translocation t(16;21)(p11;q22), resulting in the TLS/FUS::ERG fusion gene, in acute myeloid leukemia (AML). The authors utilized RT-PCR to det… (full text at CIViC) PMID 9242552 · Kong et al., 1997 · Open in CIViC	civic
〃	Diagnostic	B	Supports Positive	4	accepted	EID12322 This international retrospective study investigates the diagnostic features of acute myeloid leukemia (AML) with the t(16;21) translocation resulting in the FUS::ERG fusion gene in pediatric patients.… (full text at CIViC) PMID 30150206 · Noort et al., 2018 · Open in CIViC	civic
〃	Diagnostic	C	Supports Positive	3	accepted	EID12323 This study focuses on the diagnostic characteristics of pediatric patients with the t(16;21)(p11;q22)/FUS::ERG translocation using advanced molecular methods. The authors studied four cases of pediatr… (full text at CIViC) PMID 29427188 · Zerkalenkova et al., 2018 · Open in CIViC	civic

Data updated 20 hours agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.